Results 31 to 40 of about 208,465 (197)

Screening of HHEX Mutations in Chinese Children with Thyroid Dysgenesis. [PDF]

J Clin Res Pediatr Endocrinol, 2016
Congenital hypothyroidism (CH) is a frequent neonatal endocrine disease with an incidence of about 1:2500 worldwide. Although thyroid dysgenesis (TD) is the most frequent cause of CH cases, its pathogenesis remains unclear. The aim of this study was to screen the hematopoietically-expressedhomeobox gene (HHEX) mutations in Chinese children with TD ...
Liu S, Chai J, Zheng G, Li H, Lu D, Ge Y.   +5 more
europepmc   +3 more sources

Primary Congenital Hypothyroidism in Children Below 3 Years Old - Etiology and Treatment With Overtreatment and Undertreatment Risks, a 5-Year Single Centre Experience

Frontiers in Endocrinology, 2022
Worldwide neonatal screening for congenital hypothyroidism (CH) is a gold standard of active surveillance in newborns. Prompt diagnosis, subsequent timely treatment implementation, and proper dosage of levothyroxine (L-T4) are crucial for normal growth ...
Elżbieta Lipska, Agnieszka Lecka-Ambroziak, Agnieszka Lecka-Ambroziak, Daniel Witkowski, Katarzyna Szamotulska, Ewa Mierzejewska, Mariusz Ołtarzewski   +6 more
doaj   +1 more source

Advanced maternal age in Indian children with thyroid dysgenesis. [PDF]

Clin Pediatr Endocrinol, 2015
A retrospective review of medical records of 80 children with thyroid dysgenesis (TD) was conducted to determine the association of gender and maternal age with TD. The study subjects were attending the Pediatric Endocrinology Clinic of our hospital which is a large tertiary care Multispecialty Pediatric Center located in Chandigarh, Northwest India ...
Dayal D, Sindhuja L, Bhattacharya A, Bharti B.   +3 more
europepmc   +4 more sources

Gene expression profiles during thyroid embryonic development [PDF]

, 2009
Congenital Hypothyroidism (CH) is commonly due to structural defects of thyroid gland, collectively known as thyroid dysgenesis. Defects in growth and/or differentiation of the thyroid primordium can result in an absent (athyreosis) or hypoplastic ...
Parrillo, Luca
core   +1 more source

Three‐dimensional microscopy and image fusion reconstruction analysis of the thyroid gland during morphogenesis

FEBS Open Bio, 2021
Thyroid dysgenesis (TD) is a major cause of primary congenital hypothyroidism; however, the molecular mechanism underlying this process is unclear.
Rui‐jia Zhang, Liu Yang, Feng Sun, Ya Fang, Xiao‐ping Ye, Huai‐dong Song, Mei Dong   +6 more
doaj   +1 more source

Permanent or Transient Congenital Hypothyroidism: A Diagnostic Dilemma. [PDF]

Acta Paediatr
ABSTRACT Aim Distinguishing between transient congenital hypothyroidism (TCH) and permanent congenital hypothyroidism (PCH) remains clinically challenging and is typically deferred until the age of 2–3 years, to minimise the potential risk of adverse neurodevelopmental effects due to treatment cessation.
Dermitzaki N, Serbis A, Baltogianni M, Balomenou F, Giapros V.   +4 more
europepmc   +2 more sources

Lingual and Mediastinal Ectopic Thyroid with No Normal Thyroid Gland – A Very Rare Occurrence

Bengal Journal of Otolaryngology and Head Neck Surgery, 2019
Introduction Ectopic thyroid is a  rare  congenital  condition.  Dual ectopic  thyroid  is  rarer still with  only  30  cases  reported  in  literature.
Shyam Kalyan N, Deepjoy Basu, Mehak Agarwal, Dulal Bose   +3 more
doaj   +3 more sources

The zebrafish model to identify new genes involved in thyroid development [PDF]

, 2010
Thyroid organogenesis is a very complex developmental process that leads to the formation of an organ able to produce specific hormones through specification, migration, structural organization and functional differentiation of thyroid precursor cells ...
Porreca, Immacolata
core   +1 more source

Age-related changes of prevalence of thyroid dysgenesis.

, 2019
Age-related changes of prevalence of thyroid dysgenesis.
Hideki Hattori (7325933), Ken-ichi Nagasaki (5130728), Yuji Sunden (251928), Yaser Hosny Ali Elewa (5130725), Yasuhiro Kon (58978), Teppei Nakamura (466554), Osamu Ichii (339354), Tomoji Yoshiyasu (7325930), Osamu Tatsumi (5130731)   +8 more
core   +1 more source

Shining a Light on Hidden Thyroids: A Case Exploring the Potential of Technetium Imaging for Lingual Thyroid Diagnosis [PDF]

Journal of Clinical and Diagnostic Research
Ectopic thyroid, the presence of thyroid tissue in locations other than the normal anterior neck region between the second and fourth tracheal cartilages, is the most common form of thyroid dysgenesis.
Anbarasi Madoure, Ms Vishak, Lokesh Kumar Penubarthi   +2 more
doaj   +1 more source