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Thyroid eye disease

Seminars in Ophthalmology, 2003
Thyroid eye disease remains one of the most common orbital abnormalities encountered by ophthalmologists. While the maintenance of thyroid function remains of paramount importance to the patient's health, the appearance of the orbit, including the eyelid position and position of the globe, proptosis, remains of paramount importance to the patient ...
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Thyroid eye disease

Current Treatment Options in Neurology, 2000
The treatment of thyroid eye disease is very complex, owing to the varied nature of the symptoms and the variable course of the disease. The first step in treatment should be achieving an euthyroid state or monitoring for the development of hyperthyroidism if the patient is euthyroid at presentation.
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Management of thyroid eye disease

European Journal of Nuclear Medicine and Molecular Imaging, 2002
Thyroid eye disease (TED) is the most frequent extrathyroidal manifestation of Graves' disease. In most instances it is mild and non-progressive, but in 3%-5% of cases it is severe. Non-severe TED requires only supportive measures, such as eye ointments, sunglasses and prisms.
BARTALENA, LUIGI   +3 more
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Epidemiology of Thyroid Eye Disease

2022
A detailed understanding of the epidemiology of thyroid eye disease allows clinicians to identify and treat patients who may be at higher risk for the disease. The following manuscripts provide a detailed understanding of the epidemiology of thyroid eye disease as well as risk factors for complications of more severe disease.
Bartley G. B.   +34 more
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Phenotypes of Thyroid Eye Disease

Ophthalmic Plastic & Reconstructive Surgery, 2018
Purpose: To describe a new classification system of thyroid eye disease (TED) based on the phenotypic features (clinical and radiologic) of the disease. Methods: Clinical features, photographic, and orbital imaging of TED patients were considered in relation to their natural history
Jimmy M, Uddin   +2 more
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Recurrent Thyroid Eye Disease

Ophthalmic Plastic & Reconstructive Surgery, 2015
The natural history of thyroid eye disease follows a biphasic course featuring an initial active stage followed by a durable quiescent stage. Reactivation of thyroid eye disease is defined by recurrence of inflammatory signs and symptoms after a period of stability lasting at least 6 months. It is thought to be rare and is poorly studied.
Payal, Patel   +2 more
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Rituximab for Thyroid Eye Disease

Ophthalmic Plastic & Reconstructive Surgery, 2010
To assess the efficacy and safety of rituximab-mediated B-lymphocyte depletion as treatment for thyroid eye disease (TED).Prospective, open-label, interventional clinical trial evaluating 12 patients with TED and Clinical Activity Scores (CAS) (VISA [vision, inflammation, strabismus and appearance/exposure] classification) of 4 or greater followed for ...
Rona Z, Silkiss   +3 more
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Immunotherapies for thyroid eye disease

Current Opinion in Endocrinology, Diabetes & Obesity, 2019
Purpose of review Thyroid eye disease is a complex autoimmune disorder which causes substantial morbidity. It can result in orbital disfigurement, double vision, and visual loss. Consequently, it has a substantial negative effect on quality of life, mental health, and socioeconomic status. Most signs and symptoms of thyroid eye
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Thyroid-associated eye disease

Strabismus, 2000
Graves' ophthalmopathy (GO) is thought to result from a complex interplay of genetic and environmental factors. Various genes, including those coding for HLA, may determine a patient's susceptibility to the disease and its severity, but in addition, numerous and often unknown environmental factors may determine its course. Once established, the chronic
A E, Heufelder, W, Joba
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Noninflammatory Thyroid Eye Disease

Ophthalmic Plastic & Reconstructive Surgery, 2019
Purpose: Patients presenting with thyroid eye disease (TED) usually follow a well-defined self-remitting course characterized by an active inflammatory phase followed by an inactive fibrotic phase. We present 3 cases where patients presented primarily with signs of progressive fibrosis and no signs of prior active inflammation.
Shoaib, Ugradar, Daniel B, Rootman
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