Results 191 to 200 of about 11,036,926 (400)

Protein Spatial Structure Meets Artificial Intelligence: Revolutionizing Drug Synergy–Antagonism in Precision Medicine

open access: yesAdvanced Science, EarlyView.
This review comprehensively examines the applications of protein three‐dimensional structures and artificial intelligence in investigating drug synergistic and antagonistic effects. The research findings provide compelling evidence for the precision treatment of cancer and metabolic diseases, thereby promoting the development of personalized medicine ...
Anqi Lin   +11 more
wiley   +1 more source

Bioinspired Prolactin Pulse Release from Responsive Microneedles for Inhibiting Fatty Liver Formation

open access: yesAdvanced Science, EarlyView.
Inspired by the prolactin secretion profile under normal physiological conditions, biomimetic prolactin‐releasing microneedles are designed. Under the control of near infrared (NIR), these responsive microneedles facilitate pulsed release of prolactin to inhibit fatty liver formation.
Hongli Yin   +6 more
wiley   +1 more source

Thyroid Function of Mono- and Dizygous Cattle Twins

open access: bronze, 1959
B.N. Premachandra   +2 more
openalex   +1 more source

Comparative Single‐Cell Transcriptomic Landscape Reveals the Regulatory Mechanisms of Lactation during Selective Breeding in Asian Water Buffalo

open access: yesAdvanced Science, EarlyView.
In this study, a comprehensive single‐cell transcriptome atlas of river and swamp buffalo, encompassing 12 tissues and 397,011 cells, is constructed. Differential expression analyses identify metabolic and secretory tissues and cell types that mediate the divergence of milk production.
Dongmei Dai   +13 more
wiley   +1 more source

Thyroid Function In Vitiligo

open access: yesIndian Journal of Dermatology, 1996
Fifty vitilgo patients were studied clinically and subjected to thyroid function tests and estimation of glucose and choteserol. Clinical analysis revealed the incidence among new patients to be1.1%. The male/female ratio was 1:1.28. Patient up to
Chanda M   +4 more
doaj  

A Novel Theoretical Hypothesis on Comorbidity in the Elderly—The Disease of Sympathetic Overdrive (DSO)

open access: yesAGING MEDICINE, EarlyView.
A novel hypothesis: The disease of sympathetic overdrive (DSO) as a unifying mechanism for comorbidity in the elderly. ABSTRACT The coexistence of multimorbidity and geriatric syndromes is a big character and role target to manage for the clinic works in older age, but related theories still require innovation and exploration.
Li Jie, Kong Jian, Yu Boxin, Li Hongyang
wiley   +1 more source

Potentially Inappropriate Medications and Drug–Drug Interactions in Geriatrics Cardiac Patients Visiting to Tertiary Care Central Hospital of Nepal

open access: yesAGING MEDICINE, EarlyView.
Elderly cardiac patients are usually taking multiple medications. These cause them to encounter potentially inappropriate medications and drug–drug interactions, which increase the risk of adverse health outcomes as well as the economic burden caused by them.
Roshan Giri   +5 more
wiley   +1 more source

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