Results 31 to 40 of about 239,234 (339)

Managing toxicities associated with immune checkpoint inhibitors: consensus recommendations from the Society for Immunotherapy of Cancer (SITC) Toxicity Management Working Group. [PDF]

open access: yes, 2017
Cancer immunotherapy has transformed the treatment of cancer. However, increasing use of immune-based therapies, including the widely used class of agents known as immune checkpoint inhibitors, has exposed a discrete group of immune-related adverse ...
Abdallah, K.   +80 more
core   +2 more sources

Neurobehavioral function and low-level exposure to brominated flame retardants in adolescents : a cross-sectional study [PDF]

open access: yes, 2012
Background: Animal and in vitro studies demonstrated a neurotoxic potential of brominated flame retardants, a group of chemicals used in many household and commercial products to prevent fire.
Baeyens, Willy   +12 more
core   +1 more source

Cardiopulmonary and metabolic effects of yoga in healthy volunteers

open access: yesInternational Journal of Yoga, 2017
Background: Yoga the spiritual union of mind with the divine intelligence of the universe aims to liberate a human being from conflicts of body–mind duality.
T Satheesh Divya   +5 more
doaj   +1 more source

The Clinical Significance of Subclinical Thyroid Dysfunction. [PDF]

open access: yes, 2008
Subclinical thyroid disease (SCTD) is defined as serum free T(4) and free T(3) levels within their respective reference ranges in the presence of abnormal serum TSH levels.
BIONDI, BERNADETTE, COOPER DS
core   +1 more source

Comparison of thyroid function tests between splenectomised and non-splenectomised β-thalassemia major patients

open access: yesTikrit Journal of Pure Science, 2023
This study was to evaluate and compare thyroid function tests and serum levels of ferritin in splenectomised and non-splenectomised β-thalassemic patients.
Wasan Ayad Hadeed   +2 more
doaj   +1 more source

THYROID FUNCTION TESTS

open access: yesMedical Journal of Australia, 1980
Understanding basic thyroid physiology is essential to the proper interpretation of thyroid tests. The hypothalamus controls the pituitary gland, which regulates the thyroid in a classic feedback loop. Thyroid hormone levels are determined by thyroid state and thyroid hormone binding.
  +7 more sources

Thyroid hormone levels within reference range are associated with heart rate, cardiac structure, and function in middle-aged men and women [PDF]

open access: yes, 2013
Background: Triiodothyronine (T3) has many effects on the heart, and marked changes in cardiac function and structure occur in patients with (subclinical) thyroid disease. We investigated whether between-subject variation in thyroid hormone levels within
De Buyzere, Marc   +6 more
core   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

Thyroid Function Abnormalities among Hospital Patients of Hilly Nepal

open access: yesJournal of Lumbini Medical College, 2017
Introduction: Thyroid dysfunction stands as the second most common endocrine disease after diabetes mellitus. National reports on its prevalence are meagre.
Raj Krishna Dangol   +2 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

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