Results 31 to 40 of about 212,664 (343)

COVID-19 infection and thyroid function

Endocrine and Metabolic Science, 2022
Context: COVID-19 is a new viral infection affecting mainly the respiratory system with involvement of many other organs. Thyroid dysfunction has been described in COVID-19 but data are still unclear and conflicting on its frequency, severity and ...
Noha Mukhtar, Abdulmohsen Bakhsh, Nahlah Alreshidi, Abeer Aljomaiah, Hadeel Aljamei, Nada Alsudani, Tarek Elsayed, Roqayh Fadel, Eman Alqahtani, Ali S. Alzahrani   +9 more
doaj  

NFE2-Related transcription factor 2 coordinates antioxidant defense with thyroglobulin production and iodination in the thyroid gland [PDF]

, 2018
Background: The thyroid gland has a special relationship with oxidative stress. While generation of oxidative substances is part of normal iodide metabolism during thyroid hormone synthesis, the gland must also defend itself against excessive oxidation ...
Amendola, Elena, Bongiovanni, Massimo, Carrasco, Nancy, Chartoumpekis, Dionysios V, Habeos, Ioannis, Juvenal, Guillermo Juan, Kensler, Thomas W., Liao, Xiao-Hui, Ntalampyra, Eleni, Refetoff, Samuel, Renaud, Cédric O., Ris Stalpers, Carrie, Rossich, Luciano Esteban, Santisteban, Pilar, Somm, Emmanuel, Sykiotis, Gerasimos P., Thomasz, Lisa, Trougakos, Ioannis P, Yamamoto, Masayuki, Ziros, Panos G   +19 more
core   +1 more source

Results of Thyroid Function Tests in Premature Infants

Güncel Pediatri, 2016
Introduction: To determine the rate, etiology and morbidity association of disorders of thyroid function tests (TFTs) in premature babies. Materials and Methods: A total of 139 premature babies who were admitted to Uludag University Faculty of ...
Pelin Doğan, Erdal Eren, Cansu Canbolat   +2 more
doaj   +1 more source

Monitoring thyroid function status in elderly patients on amiodarone [PDF]

, 2006
Objectives: To evaluate whether elderly patients on amiodarone were having their thyroid function status monitored as recommended in the literature and to identify the frequency and type of thyroid function test abnormalities noted.
Fiorini, Anthony
core  

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Comparison of thyroid function tests between splenectomised and non-splenectomised β-thalassemia major patients

Tikrit Journal of Pure Science, 2023
This study was to evaluate and compare thyroid function tests and serum levels of ferritin in splenectomised and non-splenectomised β-thalassemic patients.
Wasan Ayad Hadeed, Yusra Ahmed Hussein Alhially, Ahmed Yahya Dallal Bashi   +2 more
doaj   +1 more source

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Thyroid Function Abnormalities among Hospital Patients of Hilly Nepal

Journal of Lumbini Medical College, 2017
Introduction: Thyroid dysfunction stands as the second most common endocrine disease after diabetes mellitus. National reports on its prevalence are meagre.
Raj Krishna Dangol, Priya Lanjekar, Chandrashekhar Pulipati   +2 more
doaj   +1 more source