Results 41 to 50 of about 239,234 (339)
Monitoring thyroid function status in elderly patients on amiodarone [PDF]
, 2006 Objectives: To evaluate whether elderly patients on amiodarone were having their thyroid function status monitored as recommended in the literature and to identify the frequency and type of thyroid function test abnormalities noted.
Fiorini, Anthony
core
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Thyroid Dysfunction following Radiotherapy and Combined Therapy in Non-Thyroid Head and Neck Cancers
Bengal Journal of Otolaryngology and Head Neck Surgery, 2023 INTRODUCTION: In patients with head and neck cancers thyroid gland bears the brunt in terms of either excision or irradiation resulting in loss of functionality of the gland leading to thyroid dysfunction.
Rais Ahmad Bhat +2 more
doaj +1 more source
Diagnosis and management of treatment-refractory hypothyroidism: an expert consensus report [PDF]
, 2017 There is a frequently encountered subset of hypothyroid patients who are refractory to standard thyroid hormone replacement treatment and require unexpectedly high doses of levothyroxine.
Benvenga, S +2 more
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Maternal thyroid function and child educational attainment: prospective cohort study [PDF]
, 2018 Objective: To determine if first trimester maternal thyroid dysfunction is a critical determinant of child scholastic performance and overall educational attainment. Design: Prospective cohort study.
Haig, Caroline +7 more
core +3 more sources
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Postpartum depression and thyroid dysfunction– should pregnant women be screened for thyroid disorders? [PDF]
, 2019 The relationship between thyroid dysfunction and postpartum depression has been investigated for quite some time now, but no consensus has been reached regarding the need for screening for thyroid function during pregnancy. This paper aims to investigate
Marin, Erika, Simionescu, Anca A
core +1 more source
The effect of soy phytoestrogen supplementation on thyroid status and cardiovascular risk markers in patients with subclinical hypothyroidism: A randomized, double-blind, crossover study [PDF]
, 2011 Context: There is concern whether soy phytoestrogens may affect thyroid function. If true, soy phytoestrogens may be expected to have a greater impact in subjects with subclinical hypothyroidism.
Atkin, Stephen L. +6 more
core +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source