Results 41 to 50 of about 212,664 (343)

Postpartum depression and thyroid dysfunction– should pregnant women be screened for thyroid disorders? [PDF]

, 2019
The relationship between thyroid dysfunction and postpartum depression has been investigated for quite some time now, but no consensus has been reached regarding the need for screening for thyroid function during pregnancy. This paper aims to investigate
Marin, Erika, Simionescu, Anca A
core   +1 more source

Thyroid hormone levels within reference range are associated with heart rate, cardiac structure, and function in middle-aged men and women [PDF]

, 2013
Background: Triiodothyronine (T3) has many effects on the heart, and marked changes in cardiac function and structure occur in patients with (subclinical) thyroid disease. We investigated whether between-subject variation in thyroid hormone levels within
De Buyzere, Marc, Gillebert, Thierry, Kaufman, Jean, Rietzschel, Ernst, ROEF, GREET, Taes, Youri, Van daele, Caroline   +6 more
core   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

Thyroid Dysfunction following Radiotherapy and Combined Therapy in Non-Thyroid Head and Neck Cancers

Bengal Journal of Otolaryngology and Head Neck Surgery, 2023
INTRODUCTION: In patients with head and neck cancers thyroid gland bears the brunt in terms of either excision or irradiation resulting in loss of functionality of the gland leading to thyroid dysfunction.
Rais Ahmad Bhat, Om Prakash, Shabab Lalit Angurana   +2 more
doaj   +1 more source

Diagnostic Use of Radionuclides in Diseases of the Thyroid [PDF]

, 1975
Since the introduction of radionuclides into clinical medicine, a number of specific tests have been designed to test thyroid function and to diagnose disease of the thyroid gland.
Sharpe, Alton R., Jr.
core   +1 more source

Study protocol: a randomised controlled trial on the clinical effects of levothyroxine treatment for subclinical hypothyroidism in people aged 80 years and over [PDF]

, 2018
Background: Subclinical hypothyroidism is common in older people and its contribution to health and disease needs to be elucidated further. Observational and clinical trial data on the clinical effects of subclinical hypothyroidism in persons aged 80 ...
Blum, M.R., Dekkers, O.M., Den Elzen, W.P.J., Du Puy, R.S., Ford, I., Gussekloo, J., Jukema, J.W., Kean, S., Kearney, P.M., Messow, C.M., Mooijaart, S.P., Peeters, R.P., Poortvliet, R.K.E., Postmus, I., Rodondi, N., Smit, J.W.A., Stott, D.J., van Munster, B.C., Watt, T., Westendorp, R.G.J., Wolffenbuttel, B.H.R.   +20 more
core   +8 more sources

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Puzzling thyroid function test [PDF]

BMJ Case Reports, 2017
A 13-½-year-old boy was referred to the Department of Endocrinology as a case of thyrotoxicosis for initiation of antithyroid medication. His chief complaint was a swelling in front of the neck, which was incidentally noted by his mother 2 weeks prior to presentation.
Nandhini Lakshmana Perumal, Jaya Prakash Sahoo, Sadishkumar Kamalanathan, Carla Moran   +3 more
openaire   +3 more sources

Predicting risk of malignancy in patients with indeterminate thyroid nodules [PDF]

, 2018
Thyroid cancer is the most prevalent endocrine cancer (1). The prevalence of palpable thyroid nodules in the general adult population is 4% to 7% (2). Ultrasound imaging detects thyroid nodules in 19%-68% of randomly selected individuals (3). The rate of
Carnes, Nicholas
core  

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source