Results 141 to 150 of about 308,721 (358)
Citrus Flavonoids for Cystic Fibrosis Treatment
ChemBioChem, EarlyView.Studies conducted since the late 1990s show substantial activity of selected citrus flavonoids as cystic fibrosis transmembrane conductance regulator (CFTR) membrane protein activators. The thesis of this work is that aptly formulated citrus flavonoids hold sigificant potential for developing a multitarget treatment of cystic fibrosis combining in a ...
Mario Pagliaro +5 more
wiley +1 more source
Serum thyroxin level during the first-trimester of pregnancy [PDF]
, 2011 Objective: The aim of this study was to assess the requirement of serum thyroxin levels during the early stage of the first trimester of pregnancy. Methodology: Serum thyroxin levels of 120 apparently healthy women were evaluated in Gorgan in northern ...
Mansourian, A.R. +2 more
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Clinical Pharmacology in Drug Development, EarlyView.Abstract ALG–055009 is an oral thyroid hormone receptor beta (THR‐β) agonist being evaluated for treating metabolic dysfunction–associated steatohepatitis (MASH). This study evaluated the safety, tolerability, pharmacokinetics, and pharmacodynamics of ALG‐055009 and bioavailability/food effect.
Hakim Charfi +11 more
wiley +1 more source
The effect of the extirpation of the thyroid upon the thymus and the pituitary glands of Rana pipiens [PDF]
, 1918 James B. Rogers
openalex +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Antiangiogenic therapy with bevacizumab improves outcomes in ovarian cancer but induces hypertension, leading to major adverse cardiovascular events (MACE). While calcium channel blockers (CCBs) and angiotensin‐converting enzyme inhibitors (ACEi) are recommended for managing bevacizumab‐associated hypertension, their impacts on cancer progression and ...
Floriane Jochum +10 more
wiley +1 more source
Seasonal Variation in the Activity of the Thyroid Gland of Yearling Brown Trout Salmo Trutta Linn [PDF]
, 1959 D. R. Swift
openalex +1 more source
Quantitative Approaches to Accelerate MASH Drug Discovery and Development
Clinical Pharmacology &Therapeutics, EarlyView.Metabolic dysfunction‐associated steatohepatitis (MASH) is a widespread liver condition that leads to cirrhosis, hepatic carcinoma, and increased mortality rates. In MASH, the diagnosis and accelerated approval of drugs are dependent on changes in histological endpoints; full approval requires lengthy outcomes trials.
Yasmeen Abouelhassan +6 more
wiley +1 more source
Genetic aspects of etiology and development of thyroid gland cancer [PDF]
, 2012 Recent studies on thyroid gland cancer development and progression have identified new classes of tumor markers, proto-oncogenes, tumor-suppressing genes, cell receptor genes, identified genetic tumor-predisposing polymorphism and some other ...
Kovalenko Yu.V., Tolstokorov A.S.
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A phenomap of TTR amyloidosis to aid diagnostic screening
ESC Heart Failure, Volume 12, Issue 2, Page 1113-1118, April 2025.Abstract Cardiac amyloidosis due to transthyretin (ATTR) remains an underdiagnosed cause of cardiomyopathy. As awareness of the disease grows and referrals for ATTR increase, clinicians are likely to encounter more atypical forms of the condition in clinical practice.
Alexios S. Antonopoulos +4 more
wiley +1 more source