Results 141 to 150 of about 893,341 (363)

Gene expression and pathway bioinformatics analysis detect a potential predictive value of MAP3K8 in thyroid cancer progression [PDF]

open access: yesarXiv, 2019
Thyroid cancer is the commonest endocrine malignancy. Mutation in the BRAF serine/threonine kinase is the most frequent genetic alteration in thyroid cancer. Target therapy for advanced and poorly differentiated thyroid carcinomas include BRAF pathway inhibitors.
arxiv  

III. Contributions to the minute anatomy of the thyroid gland of the dog

open access: yesProceedings of the Royal Society of London
The minute structure of the thyroid gland generally, and of its lymphatics in particular, are subjects still but imperfectly understood. With the view of elucidating the latter, the following research was made on the thyroid gland of the dog.
E. Baber
semanticscholar   +1 more source

Selection of DNA Aptamers Against Parathyroid Hormone for Electrochemical Impedimetric Biosensor System Development

open access: yesBiotechnology and Applied Biochemistry, EarlyView.
ABSTRACT This work presents the pioneering development of an aptamer‐based electrochemical biosensor for real‐time monitoring of parathyroid hormone (PTH) levels, with a focus on intraoperative assessment during parathyroid surgery. It introduces, for the first time, the selection and characterization of aptamers targeting distinct segments of the PTH ...
Reza Didarian   +5 more
wiley   +1 more source

Efficacy and Safety of Parathyroid Hormone Replacement With TransCon PTH in Hypoparathyroidism: 26‐Week Results From the Phase 3 PaTHway Trial

open access: yesJournal of Bone and Mineral Research, Volume 38, Issue 1, Page 14-25, January 2023., 2023
TransCon PTH is an investigational once‐daily prodrug providing sustained release of active PTH designed to maintain stable PTH levels in the physiological range for 24 hours/day. The PaTHway trial met all primary and key secondary endpoints with statistically significant differences from placebo. Most adverse events (AEs) were mild/moderate. Injection‐
Aliya A Khan   +19 more
wiley   +1 more source

Investigating heterogeneous PSMA ligand uptake inside parotid glands [PDF]

open access: yesPhysica Medica: European Journal of Medical Physics, 2024
The purpose was to investigate the spatial heterogeneity of prostate-specific membrane antigen (PSMA) positron emission tomography (PET) uptake within parotid glands. We aim to quantify patterns in well-defined regions to facilitate further investigations.
arxiv   +1 more source

Reduced Bone Mass and Increased Osteocyte Tartrate‐Resistant Acid Phosphatase (TRAP) Activity, But Not Low Mineralized Matrix Around Osteocyte Lacunae, Are Restored After Recovery From Exogenous Hyperthyroidism in Male Mice

open access: yesJournal of Bone and Mineral Research, Volume 38, Issue 1, Page 131-143, January 2023., 2023
ABSTRACT Hyperthyroidism causes secondary osteoporosis through favoring bone resorption over bone formation, leading to bone loss with elevated bone fragility. Osteocytes that reside within lacunae inside the mineralized bone matrix orchestrate the process of bone remodeling and can themselves actively resorb bone upon certain stimuli.
Eva Maria Wölfel   +9 more
wiley   +1 more source

Agenesis of isthmus of thyroid gland - a case report

open access: yesNational Journal of Clinical Anatomy, 2012
A wide range of morphological varieties and developmental anomalies of the thyroid gland have been reported in literature such as hypoplasia, ectopic thyroid, hemi agenesis and agenesis.
Shailajashetty   +2 more
doaj   +1 more source

Segmentation of ultrasound images of thyroid nodule for assisting fine needle aspiration cytology [PDF]

open access: yesarXiv, 2012
The incidence of thyroid nodule is very high and generally increases with the age. Thyroid nodule may presage the emergence of thyroid cancer. The thyroid nodule can be completely cured if detected early. Fine needle aspiration cytology is a recognized early diagnosis method of thyroid nodule.
arxiv  

Thyroid hormone regulation of metabolism.

open access: yesPhysiological Reviews, 2014
Thyroid hormone (TH) is required for normal development as well as regulating metabolism in the adult. The thyroid hormone receptor (TR) isoforms, α and β, are differentially expressed in tissues and have distinct roles in TH signaling.
Rashmi Mullur, Yan-Yun Liu, G. Brent
semanticscholar   +1 more source

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