Results 241 to 250 of about 308,721 (358)

Modulators of Diacylglycerol Kinase Activity: A Review of Advances and Challenges

Medicinal Research Reviews, EarlyView.
ABSTRACT Catalyzing the conversion of diacylglycerol (DAG) in phosphatidic acid (PA), diacylglycerol kinases (DGKs) play a pivotal role in all the physiological processes modulated by these two bioactive lipids, such as lipid metabolism and immune regulation.
Luisa Racca, Gianluca Baldanzi, Alberto Massarotti   +2 more
wiley   +1 more source

Tracheal Obstruction by Thyroid Gland Extension into the Trachea after Blunt Tracheal Transection. [PDF]

Surg Case Rep
Ishibashi H, Aoki M, Baba S, Fujita A, Okubo K.   +4 more
europepmc   +1 more source

The Contribution of Cholesterol and Squalene Synthase in Cancer: Molecular Mechanisms, Lipid Rafts and Therapeutic Approaches

Medicinal Research Reviews, EarlyView.
ABSTRACT A plethora of cellular signaling pathways are dysregulated in cancer cells, promoting carcinogenesis and migration. Cholesterol has recently been linked to cancer by several subcellular mechanisms, especially by its involvement in the formation of lipid rafts, which promote oncogenic signaling and cancer cell invasion. Squalene synthase (SQS),
Danai Mavridi, Theodora Katavati, Angeliki P. Kourounakis   +2 more
wiley   +1 more source

Renal cell carcinoma metastasis to the thyroid gland: a case report. [PDF]

J Med Case Rep
Hryshchyshyn A, Bahrii A, Khimich S, Bohush H, Botsun P, Chuba V.   +5 more
europepmc   +1 more source

Thyroid function tests in endemic goitre [PDF]

, 1967
Alberts, H., Beckebans, J., Richter, J., Schwarz, K., Scriba, Peter Christian   +4 more
core   +1 more source

Randomized Controlled Trial: Effects of a Bitter‐Tasting Pea Protein Hydrolysate Intervention With Low Degree of Hydrolyzation on Energy Intake in Moderately Overweight Male Subjects

Molecular Nutrition &Food Research, EarlyView.
Two pea protein hydrolysates (PPHs) reduced hunger by targeting different mechanisms: PPH1 produced a faster response in satiety and hunger hormone levels in the blood, while PPH2 had a stronger impact on gastric emptying. These effects are likely due to the differing degrees of hydrolysis between the two PPHs.
Katrin Gradl, Sonja Sterneder, Kristin Kahlenberg, Beate Brandl, Thomas Skurk, Veronika Somoza   +5 more
wiley   +1 more source

Pharmacokinetic modeling strategies for dynamic hyperpolarized urea imaging

Magnetic Resonance in Medicine, EarlyView.
Abstract Purpose To evaluate pharmacokinetic modeling methods for quantification of tissue perfusion/permeability with hyperpolarized 13C urea. Methods Three models for quantitative analysis of dynamic HP urea imaging data were proposed and evaluated in numerical simulations and a thyroid cancer mouse model.
Keith A. Michel, Collin J. Harlan, Christopher M. Walker, Matthew E. Merritt, Yunyun Chen, Stephen Y. Lai, James A. Bankson   +6 more
wiley   +1 more source

Antiobesity Medications for Older Adults—the New, the Good, the Bad, and the Unknown

Obesity, EarlyView.
ABSTRACT Objective Obesity affects 42% of older adults, with rates continuing to rise. This a complex condition influenced by non‐modifiable as well as modifiable risk factors. The disease can be treated through modifications to diet, physical activity, and behavior and more recently through antiobesity medications (AOMs) and surgery. Treatment must be
Anna Pendrey, Javier Sevilla‐Martir
wiley   +1 more source

Histological Studies of the Prenatal Development of the Human Thyroid Gland

, 1958
Akira Taki
openalex   +2 more sources

Understanding the Increasing Prevalence of Obesity in Patients With Type 1 Diabetes: Strategies for Improving Clinical Care

Obesity, EarlyView.
ABSTRACT The presence of excess weight is no longer a distinguishing feature between patients with type 1 diabetes (T1D) and those with type 2 diabetes (T2D). Obesity treatment in patients with T2D improves glycemic control and reduces or even eliminates medication burden.
Kathleen R. Ruddiman, Jessica K. Bartfield, Irl B. Hirsch   +2 more
wiley   +1 more source