Results 241 to 250 of about 313,580 (360)

Computer Vision Analysis for Objective Motor Assessment in Parkinson's Disease: A Retrospective Study

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background The Movement Disorder Society‐Unified Parkinson's Disease Rating Scale‐Part III (MDS‐UPDRS‐III) is subjective and insensitive to subtle changes in patients with Parkinson's disease (PD). Computer vision (CV) can extract objective kinematics from routine outpatient videos, potentially augmenting the accuracy of the motor assessment ...
Pasquale Maria Pecoraro   +12 more
wiley   +1 more source

Machine Learning for Predictive Modeling in Nanomedicine‐Based Cancer Drug Delivery

open access: yesMed Research, EarlyView.
The integration of AI/ML into nanomedicine offers a transformative approach to therapeutic design and optimization. Unlike conventional empirical methods, AI/ML models (such as classification, regression, and neural networks) enable the analysis of complex clinical and formulation datasets to predict optimal nanoparticle characteristics and therapeutic
Rohan Chand Sahu   +3 more
wiley   +1 more source

AGENESIS OF ISTHMUS OF THYROID GLAND [PDF]

open access: hybrid
Adesh Kumar   +3 more
openalex   +1 more source

The Contribution of Cholesterol and Squalene Synthase in Cancer: Molecular Mechanisms, Lipid Rafts and Therapeutic Approaches

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT A plethora of cellular signaling pathways are dysregulated in cancer cells, promoting carcinogenesis and migration. Cholesterol has recently been linked to cancer by several subcellular mechanisms, especially by its involvement in the formation of lipid rafts, which promote oncogenic signaling and cancer cell invasion. Squalene synthase (SQS),
Danai Mavridi   +2 more
wiley   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova   +3 more
wiley   +1 more source

Renal cell carcinoma metastasis to the thyroid gland: a case report. [PDF]

open access: yesJ Med Case Rep
Hryshchyshyn A   +5 more
europepmc   +1 more source

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