Results 171 to 180 of about 1,450,120 (315)

Inconsistent Transcriptomic Responses to Hexabromocyclododecane in Japanese Quail: A Comparative Analysis of Results From Four Different Study Designs

Environmental Toxicology and Chemistry, EarlyView.
Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers, Elena Legrand, Emily Boulanger, Niladri Basu, Jessica D. Ewald, Paula Henry, Markus Hecker, Jianguo Xia, Natalie Karouna‐Renier, Doug Crump, Jessica Head   +10 more
wiley   +1 more source

Dyslipidemia Unmasked by the Treatment of Graves' Disease: The Link Between Cholesterol Metabolism and Thyroid Hormones. [PDF]

Cureus
Sharma P.
europepmc   +1 more source

Different Configurations of Specific Thyroid Hormone Response Elements Mediate Opposite Effects of Thyroid Hormone and GC-1 on Gene Expression [PDF]

, 2005
Bernd Gloss, Gisele Giannocco, Eric A. Swanson, Anselmo Sigari Moriscot, Grazia Chiellini, Thomas S. Scanlan, John D. Baxter, Wolfgang Dillmann   +7 more
openalex   +1 more source

Integrative Evidence From Metabolome‐Wide Mendelian Randomization and Animal Models Implicates Tyrosine in Cardiac Hypercontractility and Arrhythmia Risk

Food Frontiers, EarlyView.
Plasma metabolome‐wide Mendelian randomization analysis established a causal link between tyrosine and arrhythmia. GWAS meta‐analysis identified tyrosine‐associated loci linked to cardiovascular risk factors. Animal studies confirmed that oral tyrosine intake modulates heart rhythm via adrenergic signaling activation.
Zhikang Cao, Huiying Liu, Peng Chen, Liyue Chen, Zhixin Chen, Jiaqiang Lin, Zixuan Fu, Zhipeng Li   +7 more
wiley   +1 more source

Developmental regulation of fetal mitochondrial respiratory function towards term: the role of glucocorticoid and thyroid hormones. [PDF]

J Endocrinol
Fowden AL, Davies KL, Camm EJ, Forhead AJ, Murray AJ.   +4 more
europepmc   +1 more source

Epigenetic regulation of thyroid hormone action in human metabolic dysfunction-associated steatohepatitis

Alison-Michelle Naujack, Christin Krause, Jan H. Britsemmer, Natalie Taege, Jens Mittag, Henriette Kirchner   +5 more
openalex   +1 more source

Natural Products Targeting Notch Signaling in Cancer: Mechanistic Insights and Food‐Based Chemoprevention Potential

Food Frontiers, EarlyView.
The Notch signaling pathway plays a dual role in cancer, acting as both a tumor promoter and suppressor depending on cellular context. This review highlights how natural products modulate Notch signaling to inhibit tumor initiation, progression, angiogenesis, and cancer stem cell maintenance.
Rabab Fatima, Parteek Prasher, Mousmee Sharma, Dietrich Büsselberg, Gabriela Figueroa‐González, Octavio Daniel Reyes‐Hernández, Edgar Yebrán Villegas‐Vázquez, Hernán Cortés, Gerardo Leyva‐Gómez, Jesús Herrera‐Bravo, Solomon Habtemariam, Javad Sharifi‐Rad, Monica Butnariu, Cristian Berar, Angela Caunii, William C. Cho   +15 more
wiley   +1 more source

Interaction Between Thyroid Hormones and Bone Morphogenetic Proteins in the Regulation of Steroidogenesis by Granulosa Cells. [PDF]

Int J Mol Sci
Motohashi K, Soejima Y, Yamamoto K, Iwata N, Suyama A, Nakano Y, Otsuka F.   +6 more
europepmc   +1 more source

Prenatal exposure of rare earth elements cerium and ytterbium and neonatal thyroid stimulating hormone levels: Findings from a birth cohort study

, 2019
Yunyun Liu, Mingyang Wu, Lina Zhang, Jianing Bi, Lulu Song, Lulin Wang, Bingqing Liu, Aifen Zhou, Zhongqiang Cao, Chao Xiong, Senbei Yang, Shunqing Xu, Wei Xia, Yuanyuan Li, Youjie Wang   +14 more
openalex   +1 more source

Bioactive Phytochemical Compounds in Medicago sativa L. (Alfalfa): A Systematic Review of Biological Properties and Therapeutic Relevance in Nutraceutical and Functional Food Implications

Food Frontiers, EarlyView.
ABSTRACT Medicago sativa L. (alfalfa) harbors a remarkably diverse reservoir of bioactive secondary metabolites. Flavonoids, isoflavones, and triterpenoid saponins dominate its bioactivity landscape, driving potent antioxidant, anti‐inflammatory, antimicrobial, estrogenic, hypolipidemic, and cytotoxic actions through redox modulation, membrane ...
Parham Joolaei Ahranjani, Hamid Rashidi Nodeh, Zahra Esfandiari, Giovanna Ferrentino   +3 more
wiley   +1 more source