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Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2006
Resistance to thyroid hormone (RTH) is a rare autosomal dominant inherited syndrome of reduced end-organ responsiveness to thyroid hormone. Patients with RTH have elevated serum free thyroxine (FT4) and free triiodothyronine (FT3) concentrations and normal or slightly elevated serum thyroid stimulating hormone (TSH) level.
Tolulope O Olateju, Mark Vanderpump
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Resistance to thyroid hormone (RTH) is a rare autosomal dominant inherited syndrome of reduced end-organ responsiveness to thyroid hormone. Patients with RTH have elevated serum free thyroxine (FT4) and free triiodothyronine (FT3) concentrations and normal or slightly elevated serum thyroid stimulating hormone (TSH) level.
Tolulope O Olateju, Mark Vanderpump
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Thyroid, 2020
BACKGROUND Mandatory universal salt iodization (USI) has been implemented in China for twenty years. Although iodine deficiency disorders are effectively controlled, the risk of excess iodine have been debated. METHODS A nationally representative cross-
Yongze Li +38 more
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BACKGROUND Mandatory universal salt iodization (USI) has been implemented in China for twenty years. Although iodine deficiency disorders are effectively controlled, the risk of excess iodine have been debated. METHODS A nationally representative cross-
Yongze Li +38 more
semanticscholar +1 more source
Clinics in Laboratory Medicine, 1993
Resistance to thyroid hormone encompasses a clinically heterogeneous group of conditions characterized by reduced responses of target tissues to a supply of thyroid hormone that under normal circumstances would be excessive. The syndrome of resistance to thyroid hormone is first suspected when serum thyroid hormone levels are found to be elevated in ...
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Resistance to thyroid hormone encompasses a clinically heterogeneous group of conditions characterized by reduced responses of target tissues to a supply of thyroid hormone that under normal circumstances would be excessive. The syndrome of resistance to thyroid hormone is first suspected when serum thyroid hormone levels are found to be elevated in ...
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Radioimmunoassay of Thyroid Hormones
1987The main role of the thyroid gland is to metabolize and to incorporate iodine into a variety of organic compounds, which include the metabolically active thyroid hormones, 3,5,3′,5′-tetraiodothyronine or thyroxine (T4) and 3,5,3′-triiodothyronine (T3), and several other precursors and degradation products, as summarized in Table 1 (for review see ...
Bartalena L +2 more
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Thyroid Hormones As Neurotransmitters
Thyroid, 1996During brain development, before the apparatus of neurotransmission has been set into place, many neurotransmitters act as growth regulators. In adult brain, their role in neurotransmission comes to the fore but neuronal plasticity and other growth-related processes are their continuing responsibility.
Janice T. Gordon, Mary B. Dratman
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2016
Thyroid hormones (THs) act principally through nuclear TH receptors (TRs), which are members of the nuclear hormone receptor superfamily, accompanied by gene activation or inactivation of target genes. THs exert their genomic actions such as metabolism, thermogenesis, growth, and development within several hours or days.
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Thyroid hormones (THs) act principally through nuclear TH receptors (TRs), which are members of the nuclear hormone receptor superfamily, accompanied by gene activation or inactivation of target genes. THs exert their genomic actions such as metabolism, thermogenesis, growth, and development within several hours or days.
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Thyroid, 1990
A case is presented of Graves' disease occurring in a patient with hemiagenesis of the thyroid gland. The diagnosis was suspected clinically and was confirmed by laboratory tests and imaging studies, as well as by the presence of thyroid-stimulating antibody.
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A case is presented of Graves' disease occurring in a patient with hemiagenesis of the thyroid gland. The diagnosis was suspected clinically and was confirmed by laboratory tests and imaging studies, as well as by the presence of thyroid-stimulating antibody.
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The Transport of Thyroid Hormones
Clinical Science, 19831. Hormones have to be transported from their sites of synthesis to their target organs. For lipophilic hormones, such as steroids and thyroid hormones, transport is accomplished by binding to specific serum proteins, in the case of thyroxine (T4) and tri-iodothyronine (T3) to thyroxine-binding globulin (TBG) and prealbumin (PA).
R. Hoffenberg, David B. Ramsden
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Thyroid hormone and angiogenesis
Vascular Pharmacology, 2010In models of thyroid hormone-induced cardiac hypertrophy, there is appropriate, supportive angiogenesis. Twenty years ago in one such model, angiogenesis in response to the hormone was observed before hypertrophy developed and it is now understood that iodothyronines induce neovascularization in a variety of settings, including the heart, ischemic ...
Paul J. Davis +4 more
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Thyroid hormones and the heart
Hormone Molecular Biology and Clinical Investigation, 2014Abstract Thyroid hormones have a significant impact on heart function, mediated by genomic and non-genomic effects. Consequently, thyroid hormones deficit as well as excess are expected to result in profound changes in cardiac function regulation and cardiovascular hemodynamics.
Carlos H. Sierra-Torres +1 more
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