Metabolomics‐based ageing clocks developed using blood biomarkers from over 215 000 European adults, improved the prediction of 10‐year all‐cause mortality compared to traditional models. Biological age acceleration is associated with higher mortality risk, as each additional year of metabolic age corresponded to at least 8% increased risk. These tools
Lei Peng +4 more
wiley +1 more source
Background. Fine-needle aspiration biopsy is recognized as the “gold standard” in the preoperative diagnosis of thyroid cancer. However, this method does not always allow reliable differentiation between benign and malignant thyroid nodules.
S. E. Titov +8 more
doaj +1 more source
CORRELATION OF FINE NEEDLE ASPIRATION AND FINAL HISTOPATHOLOGY IN THYROID DISEASE: A SERIES OF 702 PATIENTS MANAGED IN AN ENDOCRINE SURGICAL UNIT [PDF]
Thyroid nodules are a common clinical entity found among the adult general population. With increasing use of imaging investigations like ultrasonography, there has been a significant rise in the detection of non-palpable thyroid nodules that require ...
Maharajan, Chandrasekaran +1 more
core +1 more source
The paradox of cancer genes in non-malignant conditions: implications for precision medicine. [PDF]
Next-generation sequencing has enabled patient selection for targeted drugs, some of which have shown remarkable efficacy in cancers that have the cognate molecular signatures.
Adashek, Jacob J +3 more
core
Impact of Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features (NIFTP) on the Outcomes of Lobectomy [PDF]
Pedro Weslley Rosário
openalex +1 more source
This study identifies the SOX9/TIMP1 axis as a key regulator of immune evasion in gastric cancer. iRGD‐conjugated nanoparticles co‐delivering si‐SOX9, Ce6, and L‐Arg are developed to synergize with photodynamic therapy. The nanoplatform suppresses tumor growth, promotes dendritic cell maturation, and enhances CD8+ T‐cell activation, offering a ...
Banghua Zhong +3 more
wiley +1 more source
Struma Ovarii Associated with Pseudo- Meigs’Syndrome [PDF]
Struma ovarii is a specialized ovarian teratoma composed predominantly of mature thyroid tissue. It is associated with pleural effusion and ascites (Pseudo-Meigs’ syndrome) in 5% of cases.
Gangane, NM, Gulhane, SR, Sinha, RT
core +1 more source
Activation of the Sonic Hedgehog pathway in thyroid neoplasms and its potential role in tumor cell proliferation [PDF]
Xiulong Xu +8 more
openalex +1 more source
Diagnostic Value of Galectin-3 in Benign Thyroid Neoplasm vs. Differentiated Thyroid Carcinoma [PDF]
Matthias Kapischke
openalex +1 more source
Cytological Classification Diagnosis for Thyroid Nodules via Multimodal Model Deep Learning
This study introduces AI‐TFNA, an innovative artificial intelligence model designed to assist cytopathologists in classifying thyroid nodules based on The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC). The model effectively differentiates between benign and malignant thyroid nodules, demonstrating significant potential as a screening ...
Yuanzheng Lou +27 more
wiley +1 more source

