Results 111 to 120 of about 153,475 (357)

Development of Age‐ and Sex‐Specific Metabolomics‐Based Biological Ageing Clocks for 10‐Year Mortality Prediction

open access: yesAdvanced Science, EarlyView.
Metabolomics‐based ageing clocks developed using blood biomarkers from over 215 000 European adults, improved the prediction of 10‐year all‐cause mortality compared to traditional models. Biological age acceleration is associated with higher mortality risk, as each additional year of metabolic age corresponded to at least 8% increased risk. These tools
Lei Peng   +4 more
wiley   +1 more source

ANALYSIS OF RELATIVE EXPRESSION OF THE HMGA2 GENE AND ONCOGENIC MICRORNA-221 IN CYTOLOGICAL SLIDES OBTAINED BY A FINE-NEEDLE ASPIRATION BIOPSY OF THE THYROID NODULES

open access: yesУспехи молекулярной онкологии, 2017
Background. Fine-needle aspiration biopsy is recognized as the “gold standard” in the preoperative diagnosis of thyroid cancer. However, this method does not always allow reliable differentiation between benign and malignant thyroid nodules.
S. E. Titov   +8 more
doaj   +1 more source

CORRELATION OF FINE NEEDLE ASPIRATION AND FINAL HISTOPATHOLOGY IN THYROID DISEASE: A SERIES OF 702 PATIENTS MANAGED IN AN ENDOCRINE SURGICAL UNIT [PDF]

open access: yes, 2012
Thyroid nodules are a common clinical entity found among the adult general population. With increasing use of imaging investigations like ultrasonography, there has been a significant rise in the detection of non-palpable thyroid nodules that require ...
Maharajan, Chandrasekaran   +1 more
core   +1 more source

The paradox of cancer genes in non-malignant conditions: implications for precision medicine. [PDF]

open access: yes, 2020
Next-generation sequencing has enabled patient selection for targeted drugs, some of which have shown remarkable efficacy in cancers that have the cognate molecular signatures.
Adashek, Jacob J   +3 more
core  

Targeting the SOX9/TIMP1 Axis with iRGD‐Conjugated Nanoplatform Enhances Dendritic Cell Function and Photodynamic Immunotherapy in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
This study identifies the SOX9/TIMP1 axis as a key regulator of immune evasion in gastric cancer. iRGD‐conjugated nanoparticles co‐delivering si‐SOX9, Ce6, and L‐Arg are developed to synergize with photodynamic therapy. The nanoplatform suppresses tumor growth, promotes dendritic cell maturation, and enhances CD8+ T‐cell activation, offering a ...
Banghua Zhong   +3 more
wiley   +1 more source

Struma Ovarii Associated with Pseudo- Meigs’Syndrome [PDF]

open access: yes, 2012
Struma ovarii is a specialized ovarian teratoma composed predominantly of mature thyroid tissue. It is associated with pleural effusion and ascites (Pseudo-Meigs’ syndrome) in 5% of cases.
Gangane, NM, Gulhane, SR, Sinha, RT
core   +1 more source

Activation of the Sonic Hedgehog pathway in thyroid neoplasms and its potential role in tumor cell proliferation [PDF]

open access: bronze, 2012
Xiulong Xu   +8 more
openalex   +1 more source

Cytological Classification Diagnosis for Thyroid Nodules via Multimodal Model Deep Learning

open access: yesAdvanced Science, EarlyView.
This study introduces AI‐TFNA, an innovative artificial intelligence model designed to assist cytopathologists in classifying thyroid nodules based on The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC). The model effectively differentiates between benign and malignant thyroid nodules, demonstrating significant potential as a screening ...
Yuanzheng Lou   +27 more
wiley   +1 more source

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