Results 81 to 90 of about 137,477 (311)
AI‐Guided SERS Defines a Pan‐Cancer Diagnostic Biomarker
An AI‐enabled SERS platform integrates automated exosome enrichment with molecular fingerprinting to enable accurate early detection and differential diagnosis of ten common cancers. The system identifies exosomal dATP as a universal Raman biomarker, offering a scalable, noninvasive, and clinically translatable approach for precision oncology ...
Cai Zhang +15 more
wiley +1 more source
This study demonstrates meningeal lymphatic impairment associated with lung adenocarcinoma brain metastasis progression in both human patients and mouse models, establishes clinically applicable non‐invasive imaging biomarkers for quantitative analyzing mLV structure and function, and reveals mLVs as robust prognostic indicators and promising potential
Yuan Zhang +15 more
wiley +1 more source
A case of synchronous hurthle cell adenoma of thyroid and para thyroid adenoma
Synchronous hurthle cell adenoma of thyroid and para thyroid adenoma is very rare .Here we dicuss a 46 year old woman who presented with a thyroid nodule. Thyroid function test was normal but she had mild hypercalcemia.
Masoome Tohidi +4 more
doaj
Frontal bone metastasis from an occult follicular thyroid carcinoma: Diagnosed by FNAC
Metastatic deposits in skull bones from follicular thyroid carcinoma is rare, and metastatic disease in skull being the presenting symptom without obvious thyroid lesion (occult primary) is even rarer.
Rajnish Kalra +5 more
doaj +1 more source
Diagnostic Value of Galectin-3 in Benign Thyroid Neoplasm vs. Differentiated Thyroid Carcinoma [PDF]
Matthias Kapischke
openalex +1 more source
GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu +11 more
wiley +1 more source
Thyroid Carcinoma Showing Thymic-Like Differentiation Causing Fracture of the Trachea
Thyroid carcinoma showing thymic-like differentiation (CASTLE) comprises a rare neoplasm of the thyroid gland which arises from ectopic thymic tissue or remnants of brachial pouches.
Aikaterini Marini +5 more
doaj +1 more source
Diffuse Goiter and Severe Hypothyroidism due to Metastasis to the Thyroid
Despite the fact that the thyroid is a highly vascularized organ, clinically significant metastatic spread to the thyroid is considered uncommon. Hypothyroidism due to these metastases seldom occurs.
Anastasios Gkountouvas +5 more
doaj +1 more source
Integrin β3 Orchestrates Hepatic Steatosis via a Novel CD36‐Dependent Lipid Uptake Complex
In MASH, ITGB3 recruits LYN and drives its ubiquitin‐proteasomal degradation via phosphorylation. This relieves DHHC5 inhibition, enabling ITGB3/DHHC5/CD36 complex assembly to enhance CD36 palmitoylation and fatty acid uptake, thereby exacerbating disease. Targeting ITGB3 blocks this pathogenic axis and ameliorates MASH.
Ying Zhang +13 more
wiley +1 more source

