Results 101 to 110 of about 901,712 (292)

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Low frequency of TERT promoter mutations in a series of well-differentiated follicular-patterned thyroid neoplasms

, 2017
The diagnostic and clinical approaches to follicular-patterned thyroid neoplasms often create dilemmas for pathologist and clinicians. The molecular analysis of these tumors could be a useful tool to overcome diagnostic limitations.
PROIETTI, AGNESE, A. Proietti, BORRELLI, NICLA, VITTI, PAOLO, SARTORI, CHIARA, MATERAZZI, GABRIELE, G. Materazzi, E. Macerola, P. Vitti, C. Sartori, F. Basolo, BASOLO, FULVIO, MACEROLA, ELISABETTA, N. Borrelli   +13 more
core   +1 more source

Exposure‐adjusted safety and efficacy of GLP‐I and GLP‐1/GIP receptor agonists compared with non‐GLP‐I for weight management and type 2 diabetes: Based on FDA medical and statistical reports of 34 280 safety and 36 312 efficacy subjects

British Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad, Anshu Arora, Arun Arora, Jeena Vaid, Arif Khan   +4 more
wiley   +1 more source

Increasing the reporting of adverse drug reaction‐related hospitalizations using an ICD‐10‐based identification workflow: A multicentre study from Switzerland

British Journal of Clinical Pharmacology, EarlyView.
Background Reporting adverse drug reactions (ADRs) is essential for drug safety. In Switzerland, healthcare professionals are legally required to report serious and unlabelled ADRs, yet under‐reporting remains widespread. We tested a novel method to increase reporting of ADR‐related hospitalizations.
Georgia Anita Weber, Sophie‐Charlotte Bartel, Michael Boch, Christoph Rosen, Michael Bodmer, Balthasar Luzius Hug, Thomas Stammschulte, Patrick E. Beeler   +7 more
wiley   +1 more source

Histopathological Analysis and Study of Expression of Prostate Specific Membrane Antigen (PSMA) in Thyroid Follicular Neoplasms [PDF]

, 2019
BACKGROUND: Thyroid cancer is one of common endocrine cancers. Thyroid follicular neoplasms includes Follicular Adenoma, Follicular carcinoma and Follicular variant of Papillary Carcinoma.
Syed Abdullah Mohamed Ameen,
core  

Impact of empiric potassium supplementation on mortality, sudden cardiac arrest and stroke in furosemide initiators

British Journal of Clinical Pharmacology, EarlyView.
Aim A prior non‐randomized study suggests that potassium supplementation may improve survival among furosemide initiators, and a randomized trial suggests that salt substitutes containing potassium might lower stroke risk. We conducted a retrospective cohort study using health‐care data to confirm or refute these associations among new users of ...
Thanh Phuong Pham Nguyen, Sean Hennessy, Colleen M. Brensinger, Warren B. Bilker, Laura M. Dember, Todd A. Miano, Tat‐Thang Vo, Allison W. Willis, Charles E. Leonard   +8 more
wiley   +1 more source

Cytologic Diagnosis of Oncocytic Neoplasms of the Thyroid Gland: The Importance of the Clinical Scenario.

, 2019
Cytologic Diagnosis of Oncocytic Neoplasms of the Thyroid Gland: The Importance of the Clinical ...
Straccia P, Fadda G., Guido Fadda, Patrizia Straccia, Pierconti F, Giuseppe Santeusanio, Chiara Brunelli, Francesco Pierconti, Brunelli C   +8 more
core   +1 more source

Histopathological Patterns of Thyroid Follicular Neoplasms in Sudanese Patients

, 2012
Background: Thyroid follicular neoplasms are common thyroid problem and show a broad range of overlapping clinical and cytologic features and according to the world epidemiologic data, follicular carcinoma is the second most common thyroid neoplasm ...
Abboh, Emad
core  

ISL1 expression is not restricted to pancreatic well-differentiated neuroendocrine neoplasms, but is also commonly found in well and poorly differentiated neuroendocrine neoplasms of extrapancreatic origin

, 2013
The human insulin gene enhancer-binding protein islet-1 (ISL1) is a transcription factor involved in the differentiation of the neuroendocrine pancreatic cells.
Hartmann, Arndt, Konukiewitz, Björn, Agaimy, Abbas, Rieker, Ralf J., Erlenbach-Wünsch, Katharina, Vieth, Michael, Kiesewetter, Franklin, Schmitt Kurrer, Anja, Zamboni, Giuseppe, Perren, Aurel, Klöppel, Günter   +10 more
core   +1 more source

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source