Results 101 to 110 of about 169,224 (257)

Regulatory harmonization: Evolution, globalization and future directions

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm   +2 more
wiley   +1 more source

Evaluation of GARP immunohistochemical expression in papillary thyroid carcinoma

open access: yesThe Egyptian Journal of Otolaryngology
Background Glycoprotein A repetitions predominant (GARP) is a novel transmembrane protein highly expressed on the surface of regulatory T cells (Tregs), which are a subset of immunosuppressive T lymphocytes that play a major role in inhibiting the ...
Esraa Adel Mahmoud Mohamed Atia   +4 more
doaj   +1 more source

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

open access: yesBMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng   +4 more
wiley   +1 more source

Thyroid Neoplasms following Irradiation [PDF]

open access: yesBMJ, 1958
G M, WILSON   +6 more
openaire   +2 more sources

Refractive Index–Correlated Pseudocoloring for Adaptive Color Fusion in Holotomographic Cytology

open access: yesCytometry Part A, EarlyView.
ABSTRACT Conventional bright‐field (BF) cytology of thyroid fine‐needle aspiration biopsy (FNAB) suffers from staining variability and limited subcellular contrast. Here, we present a refractive index–correlated pseudocoloring (RICP) framework that integrates quantitative refractive index (RI) maps obtained by holotomography (HT) with color BF images ...
Minseok Lee   +8 more
wiley   +1 more source

Impact of Operator Specialization and on‐Site Evaluation on Nondiagnostic Thyroid Fine‐Needle Aspiration: A Comparative Study

open access: yesDiagnostic Cytopathology, EarlyView.
ABSTRACT Background Thyroid fine‐needle aspiration (FNA) is the primary diagnostic method for evaluating thyroid nodules; however, nondiagnostic results remain a significant limitation, often leading to repeat procedures and delayed diagnosis. Operator specialization and rapid on‐site evaluation (ROSE) have been proposed as strategies to improve ...
Fatlinda Sadiku   +2 more
wiley   +1 more source

Utility of Fine Needle Aspiration Supernatant for Real‐Time PCR–Based Mutation Analysis in Non–Small Cell Lung Cancer

open access: yesDiagnostic Cytopathology, EarlyView.
ABSTRACT Background The emergence of personalized therapy and molecular sequencing has significantly transformed the management of advanced non–small cell lung carcinoma (NSCLC). Supernatants obtained from fine needle aspiration (FNA) have been shown to be a reliable source of high‐quality nucleic acid for molecular testing.
Adeyinka Akinsanya   +9 more
wiley   +1 more source

Assessing Clinical Severity and Prognosis in Adolescents With Anorexia Nervosa and Atypical Anorexia Nervosa Using the Albumin‐Globulin Ratio

open access: yesEuropean Eating Disorders Review, EarlyView.
ABSTRACT Objective The albumin‐globulin ratio (AGR) is a biochemical marker reflecting nutritional and inflammatory status, with significant prognostic value in chronic conditions. This study examined its association with clinical/biochemical markers in adolescents with anorexia nervosa (AN) and atypical AN (AAN).
Eylem Şerife Kalkan   +5 more
wiley   +1 more source

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