Update from the 2022 World Health Organization Classification of Thyroid Tumors: A Standardized Diagnostic Approach [PDF]
Endocrinology and Metabolism, 2022 The fifth edition of the World Health Organization (WHO) histologic classification of thyroid neoplasms released in 2022 includes newly recognized tumor types, subtypes, and a grading system.
Chan Kwon Jung +2 more
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Immunohistochemistry in the pathologic diagnosis and management of thyroid neoplasms. [PDF]
Front Endocrinol (Lausanne), 2023 The use of immunohistochemistry cannot be underestimated in the everyday practice of thyroid pathology. It has evolved over the years beyond the traditional confirmation of thyroid origin to molecular profiling and the prediction of clinical behavior. In
Crescenzi A, Baloch Z.
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Genetics, Diagnosis, and Management of Hürthle Cell Thyroid Neoplasms. [PDF]
Front Endocrinol (Lausanne), 2021 Hürthle cell lesions have been a diagnostic conundrum in pathology since they were first recognized over a century ago. Controversy as to the name of the cell, the origin of the cell, and even which cells in particular may be designated as such still ...
McFadden DG, Sadow PM.
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Deep learning prediction of BRAF-RAS gene expression signature identifies noninvasive follicular thyroid neoplasms with papillary-like nuclear features. [PDF]
Mod Pathol, 2021 Noninvasive follicular thyroid neoplasms with papillary-like nuclear features (NIFTP) are follicular-patterned thyroid neoplasms defined by nuclear atypia and indolent behavior. They harbor RAS mutations, rather than BRAFV600E mutations as is observed in
Dolezal JM +9 more
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Pathology and new insights in thyroid neoplasms in the 2022 WHO classification. [PDF]
Curr Opin Oncol, 2023 Purpose of review The assessment of thyroid nodules is a common clinical problem, linked to the high incidence of thyroid nodules in the population and the low incidence of aggressive thyroid carcinoma.
Lebrun L, Salmon I.
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JAMA Otolaryngol Head Neck Surg, 2022 Importance Increasing detection of early-stage papillary thyroid neoplasms without improvements in mortality has prompted development of strategies to prevent or mitigate overtreatment.
Caulley L +33 more
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Diagnostic Utility of Immunohistochemistry Markers Galectin-3, CK19 and CD56 in Thyroid Neoplasms: A Descriptive Study [PDF]
Journal of Clinical and Diagnostic Research, 2022 Introduction: The spectrum of follicular patterned thyroid lesions vary from benign to malignant, their categorisation based solely on morphology can often be equivocal.
Jayasree Raman +2 more
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HBME-1 expression by thyroid neoplasms in a Nigerian tertiary health Centre
Ibom Medical Journal, 2023 Aim: The aim of this study is to review the histopathological diagnosis of thyroid neoplasms seen in OAUTHC Ile Ife using HBME-1 immunohistochemical marker. Materials and methods: We studied all thyroid neoplasms diagnosed in the Department of Morbid
Soremekun AI, Olaofe OO, Komolafe AO
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Activation of the Sonic Hedgehog pathway in thyroid neoplasms and its potential role in tumor cell proliferation [PDF]
Endocrine-Related Cancer, 2012 The sonic hedgehog (SHH) pathway is activated in several types of malignancy and plays an important role in tumor cell proliferation and tumorigenesis. SHH binding to a 12-pass transmembrane receptor, Patched (PTCH), leads to freeing of Smoothened (SMO ...
Xiulong Xu +8 more
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