Results 221 to 230 of about 193,981 (306)

Reversal of Canities in a Patient With Frontal Fibrosing Alopecia

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Frontal fibrosing alopecia (FFA) is a primary lymphocytic cicatricial alopecia, most commonly affecting postmenopausal women, characterized by progressive frontotemporal hairline recession and eyebrow loss. Hair repigmentation (canities reversal) is an extremely rare event, especially in older individuals with long‐standing white hair.
Nicolò Rivetti
wiley   +1 more source

Spatially Resolved Molecular Characterization of Noninvasive Follicular Thyroid Neoplasms with Papillary-like Nuclear Features (NIFTPs) Identifies a Distinct Proteomic Signature Associated with RAS-Mutant Lesions. [PDF]

open access: yesInt J Mol Sci
Denti V   +17 more
europepmc   +1 more source

TET3‐Mediated m5C Modification of CCAT2 Accelerates Cardiac Microvascular Endothelial Cell Damage in Acute Coronary Syndrome

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Acute coronary syndrome (ACS) is a clinical syndrome involving myocardial ischemia. This study aimed to elucidate the mechanism of TET3 in ACS‐induced CMEC damage, thereby identifying a new target for ACS treatment. The expression of TET3 in ACS patients and healthy subjects was analyzed.
Jun‐Cheng Liu   +5 more
wiley   +1 more source

Proteomics‐Based Identification of the Pyroptosis‐Related Biomarker PCSK9 and Its Association With the Pathogenesis of Rheumatoid Arthritis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Rheumatoid arthritis (RA) is a common autoimmune disease, and early diagnosis is critical for effective treatment. This study aims to identify potential biomarkers related to pyroptosis through serum proteomics analysis, offering new insights for the early diagnosis of RA.
Lei Wang   +10 more
wiley   +1 more source

PRDM1 Knockdown Promotes Ferroptosis and Sunitinib Sensitivity by Modulating the PI3K/Akt Signaling Through Inhibition of ESM1 Transcription in Renal Cell Carcinoma

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Renal cell carcinoma (RCC) is a commonly occurring and considerable burden on public health. Although chemotherapy benefits patients with advanced RCC, sunitinib resistance leads to a poor prognosis. Ferroptosis is also involved in sunitinib resistance in RCC.
Yi‐Shuai Zhang   +5 more
wiley   +1 more source

Metabolic Dysfunction‐Associated Steatotic Liver Disease and Obesity: Pathogenesis, Diagnostics, Risk Stratification, and Therapeutic Approach

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide, closely linked to the global rising incidence of obesity and metabolic syndrome. This review synthesizes current evidence on the pathogenesis, gut–liver axis, and multidisciplinary management of MASLD within the ...
Beom Kyung Kim
wiley   +1 more source

Choice and Death: Analysis of Medical Assistance in Dying for Head and Neck Cancer in Ontario

open access: yesThe Laryngoscope, EarlyView.
The uptake of MAiD for head and neck cancer (HNC) has been steadily increasing since 2016, when MAiD first became available in Canada. Our study projects a substantial increase in the future use of MAiD for patients with HNC. As such, our health system needs to re‐evaluate and implement the necessary infrastructure to support the projected increase in ...
Tanika Curry   +8 more
wiley   +1 more source

ACR‐TIRADS Institution and Effect on Thyroid Surgeries in Veterans: A 10‐Year Retrospective Study

open access: yesThe Laryngoscope, EarlyView.
Following analysis of the adoption of ACR TI‐RADS at the VA Northern California Healthcare System, the number of thyroid ultrasounds and FNAs increased substantially, while the total number of thyroid surgeries remained relatively stable. Surgical practice trends towards more selective and less‐invasive management, with fewer total thyroidectomies for ...
Isabella W. Leon   +4 more
wiley   +1 more source

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