Results 61 to 70 of about 901,712 (292)

The Potential Diagnostic Utility of TROP-2 in Thyroid Neoplasms

Applied immunohistochemistry & molecular morphology (Print), 2016
Objectives: Human trophoblast cell-surface marker (TROP-2) has been reported to be overexpressed in various human carcinomas (CAs) and suggested to be a prognostic marker for some CAs.
Haiyan Liu, Jianhui Shi, F. Lin
semanticscholar   +1 more source

Proton Magnetic-Resonance and Human Thyroid Neoplasia-Ii - Potential Avoidance of Surgery for Benign Follicular Neoplasms

, 1994
Thyroid cancer is rare, but many thyroidectomies continue to be performed simply to exclude a diagnosis of malignancy. The purpose of this study was to determine the potential financial savings associated with the use of proton magnetic resonance ...
Dowd, Susan, Reeve, TS, Delbridge, Leigh, Mountford, CE, Mountford, Carolyn E., Dowd, S, Russel, Peter, Roman, Sandrine K., Delbridge, L, Russel, P, Reeve, Thomas S., Lean, CL, May, George L., May, GL, Lean, Cynthia L., Roman, S   +15 more
core   +1 more source

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source

Two-dimensional proton magnetic resonance spectroscopy for tissue characterization of thyroid neoplasms

, 1996
We have previously demonstrated that one dimensional (1D) proton (1H) magnetic resonance spectroscopy (MRS) can distinguish normal thyroid tissue from thyroid carcinoma using a spectral ratio of peak intensity at 1.7 ppm/0.9 ppm.
Dowd, Susan, Mackinnon, WB, Delbridge, Leigh, Mountford, CE, Mountford, Carolyn E., Russell, P, Russell, Peter, Dowd, S, Mackinnon, Wanda B., Delbridge, L, Lean, CL, Doran, Sinead, May, George L., May, GL, Lean, Cynthia L., Doran, S   +15 more
core   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

FNAC accuracy in diagnosis of thyroid neoplasms considering all diagnostic categories of the Bethesda reporting system: A single-institute experience

Journal of Cytology, 2015
Background: Thyroid fine-needle aspiration cytology (FNAC) is a valuable test used for diagnosing diseases of the thyroid gland. Aims: Using all satisfactory categories of the Bethesda system, this study aimed to determine the accuracy with which FNAC ...
F. Hajmanoochehri, Elham Rabiee
semanticscholar   +1 more source

Molecular Genetics of Human Thyroid Neoplasms

, 1994
Cancers are thought to develop as a result of sequential mutations of genes important in the control of cellular growth. Recently investigators identified a number of genetic defects that affect oncogenes and tumor-suppressor genes and that provide ...
James A. Fagin
core   +1 more source

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit   +20 more
wiley   +1 more source

European multicentre study on outcome of surgery for sporadic primary hyperparathyroidism

BJS (British Journal of Surgery), EarlyView., 2020
Some 5861 patients undergoing first‐time surgery for sporadic primary hyperparathyroidism were registered in the Eurocrine® database between 2015 and 2018. The use of intraoperative parathyroid hormone measurement decreased the risk of conversion and persistent hypercalcaemia.
A. Bergenfelz, S. van Slycke, Ö. Makay, L. Brunaud   +3 more
wiley   +1 more source

Galectin-3 Immunohistochemical Expression in Thyroid Neoplasms.

Journal of clinical and diagnostic research : JCDR, 2015
BACKGROUND Galectin-3 has been implicated in the regulation of cellular growth, differentiation and malignant transformation in various organs including thyroid gland.
B. Sumana, S. Shashidhar, A. Shivarudrappa   +2 more
semanticscholar   +1 more source