Results 161 to 170 of about 66,584 (311)

Pancreatic Neuroendocrine Tumor Leading to a Diagnosis of Multiple Endocrine Neoplasia Type 1

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Pancreatic neuroendocrine neoplasms are rare but occasionally encountered. They are generally highly vascularized solid tumors, often round in shape with clear boundaries, defined contours, and a homogeneous internal structure. However, they can also present with atypical features, such as cystic degeneration, hemorrhage, calcification, and ...
Noriyuki Hirakawa   +9 more
wiley   +1 more source

Small Intestinal Metastasis From Pulmonary Large Cell Carcinoma Detected by Capsule Endoscopy and Balloon‐assisted Endoscopy, Followed by Early Surgical Resection: A Case Report

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Metastasis of lung cancer to the small intestine is rare and often diagnosed only after life‐threatening complications such as perforation or obstruction. We report a case of small intestinal metastasis from pulmonary large cell carcinoma, diagnosed using balloon‐assisted endoscopy (BAE) performed for obscure gastrointestinal bleeding (OGIB ...
Yoshihiro Yokota   +9 more
wiley   +1 more source

An OGT Missense Variant With Impaired Enzyme Activity in a Child With Severe Developmental Delay and Hepatoblastoma

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 2, Page 502-510, February 2026.
ABSTRACT O‐GlcNAc transferase (OGT) and its antagonist O‐GlcNAcase (OGA) regulate protein O‐GlcNAcylation, a highly conserved post‐translational modification involved in metabolic sensing. Pathogenic variants in the OGT gene cause an X‐linked congenital disorder of glycosylation (OGT‐CDG) presenting developmental delay, hypotonia, intellectual ...
Alfonso Manuel D'Alessio   +12 more
wiley   +1 more source

Rare Coexistence of Monilethrix and Trichorrhexis Nodosa in a Pediatric Patient: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Monilethrix is a rare genetic disorder characterized by sparse, brittle hair, primarily affecting the scalp, although it may also affect other parts of the body. Trichorrhexis nodosa (TN) is another hair shaft disorder characterized by brittle and fragile hair shafts. Concurrence of monilethrix and TN is exceedingly rare.
Yasamin Dehghan, Mozhdeh Sepaskhah
wiley   +1 more source

Primary Hyperparathyroidism With Brown Tumor—A Case Mistaken as Non‐Ossifying Fibroma Resolved by Biochemical and Radiological Correlation

open access: yesClinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Primary hyperparathyroidism (PHPT) is uncommon in the pediatric population and rarely presents with overt skeletal complications such as brown tumors. This case study describes a 16‐year‐old female who initially presented with abdominal pain and was subsequently found to have severe hypercalcemia (serum calcium 16.4 mg/dL) and markedly ...
Dosti Regmi   +4 more
wiley   +1 more source

Molecular testing and other metrics in thyroid cytology as quality‐assurance measures in evaluating variation among pathologists in the diagnosis of atypia of undetermined significance

open access: yesCancer Cytopathology, Volume 134, Issue 2, February 2026.
Abstract Background Atypia of undetermined significance (AUS) is a subjective diagnosis with reported interinstitutional rates ranging from 1% to 20%. The Bethesda System for Reporting Thyroid Cytology (TBS) endorsed ≤10% as an achievable target; however, lowering AUS rates without informed, adjusted diagnostic thresholds can compromise the sensitivity
Tarik M. Elsheikh   +8 more
wiley   +1 more source

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