Environmental toxicants may disrupt developmental pathways via strong molecular docking interactions with hub FGF proteins (FGF9 and FGF4) like dibenzo‐p‐dioxin (−7.2 kcal/mol) at the ASN146 residue of FGF9, driving congenital malformations as revealed by PPI networks and toxicity profiling.
Adarsh Kumar Shukla +3 more
wiley +1 more source
Real-world agreement in the ultrasound classification of subcapsular thyroid nodules: comparison with expert assessment. [PDF]
Trimboli P +7 more
europepmc +1 more source
Toward Autonomous Clinics: Human–Robot Collaboration in Clinical Care
This graphical abstract summarizes the conceptual structure of human–robot collaboration (HRC) for autonomous clinical systems. The framework is organized around a dual‐brain architecture in which a professional brain supports clinical reasoning tasks such as diagnosis, image analysis, treatment planning, and patient monitoring, while a physical brain ...
Xinyuan Wu +8 more
wiley +1 more source
When cytology misses and ultrasound warns: the predictive role of BRAFV600E mutation in thyroid nodules. [PDF]
Jie L +11 more
europepmc +1 more source
The Role of Thyroidectomy in the Management of Thyroglossal Duct Carcinoma: A Systematic Review
Abstract Objective The extent of surgical management of thyroglossal duct‐associated differentiated thyroid carcinoma remains controversial. This study aims to evaluate the role of total thyroidectomy in patients with thyroglossal duct‐associated differentiated thyroid carcinoma and provide insights to support individualized, evidence‐based care.
Hidde H. IJtsma +6 more
wiley +1 more source
Serum Thyroid Biomarkers for Diagnosing Malignant Thyroid Nodules: A Machine Learning Approach with External and Causal Validation. [PDF]
Gu Q +10 more
europepmc +1 more source
Abstract Objective Artificial intelligence (AI) has advanced to simultaneously process visual, auditory, and textual inputs, providing users with “multimodal” AI. Given the clinical integration potential of these tools, otolaryngologists must stay informed. This study reviews current literature on applications of multimodal AI in otolaryngology.
Ying Jie Li +5 more
wiley +1 more source
Predicting malignancy in solid thyroid nodules with no or punctate-linear enhancement on contrast-enhanced ultrasound: a retrospective analysis. [PDF]
Kang R, Tang J, Zhang Y, Ma J, Zhang B.
europepmc +1 more source
The Molecular Heterogeneity of NRAS Variants in Thyroid Nodules
Abstract Objective NRAS variants are the most common mutations in thyroid nodules with (B)ethesda III/IV cytology. This study aims to characterize co‐occurring variants, molecular signatures, and hallmarks of cancer pathways in nodules with NRAS variants. Study Design Retrospective database analysis.
Emma De Ravin +5 more
wiley +1 more source
Emotional burden of TI-RADS 4 thyroid nodules: clinical and psychosocial correlation. [PDF]
Zhang J, Liang X, Teng Y, Li S, Zhang H.
europepmc +1 more source

