Results 181 to 190 of about 100,778 (309)

Evaluation of Potential Hormonal Activities of Ashwagandha (Withania somnifera)

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Ashwagandha is a widely used herb in traditional medicine systems, particularly Ayurveda. Despite its extensive tradition, growing concerns regarding its potential endocrinological effects have prompted scientific scrutiny. This review systematically evaluates the current preclinical, clinical, and case study evidence concerning AS's effects ...
Günter Vollmer, Thomas Brendler
wiley   +1 more source

Safety Evaluation of an Aqueous Root and Leaf Extract of Ashwagandha (Withania somnifera)

open access: yesPhytotherapy Research, EarlyView.
Sensoril, an aqueous root and leaf extract of ashwagandha showed no evidence of mutagenicity in the in vitro Ames assay, was negative in the in vitro micronucleus, in vivo mammalian bone marrow chromosome aberration assays, and was well tolerated in the rat at up to 4000 mg/kg BW/day when administered orally for a period of 90 days. The data from these
Mukesh Summan   +2 more
wiley   +1 more source

Flavonoids in Nasal Therapeutics: Biological Activities, Delivery Challenges, and Formulation Strategies–A Systematic Review

open access: yesPhytotherapy Research, EarlyView.
Overview of the therapeutic potential of flavonoids in nasal delivery systems, highlighting their benefits to the human nasal cavity, and applications in the treatment of respiratory and brain‐related diseases. ABSTRACT Flavonoids represent a significant group of secondary metabolites.
Jeniffer Viviana Ramirez Hernández   +5 more
wiley   +1 more source

Progress On Sensorineural Hearing Loss: Mechanisms and Therapies

open access: yesSensory Neuroscience, EarlyView.
ABSTRACT Hearing loss is the most common disabling disease among humans, which adversely affects human health. Sensorineural hearing loss (SNHL) accounting for approximately 63% of all hearing loss cases. SNHL may be classified into age‐related hearing loss (ARHL), drug‐induced hearing loss (DIHL), noise‐induced hearing loss (NIHL), and sudden ...
Yuan Zhang   +9 more
wiley   +1 more source

Ultrasensitive Detection of Neurofilament Light in Plasma Using F(Ab’)2‐Modified Graphene Field‐Effect Biosensor

open access: yesSmall, EarlyView.
An antibody fragment (F(ab')2)‐modified graphene field‐effect transistor biosensor is developed for the ultrasensitive detection of neurofilament light chain in clinical plasma. By reducing the Debye screening effect, the platform achieves a 114% sensitivity increase and a fivefold lower detection limit compared to whole‐antibody approaches ...
Selvinaz Burcu Kizilates   +16 more
wiley   +1 more source

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