Results 11 to 20 of about 82,091 (205)

Complications after medullary thyroid carcinoma surgery: multicentre study of the SQRTPA and EUROCRINE® databases

open access: yesBJS (British Journal of Surgery), EarlyView., 2020
This study investigated postoperative complications after surgery for medullary thyroid carcinoma (MTC) in Europe. Hypoparathyroidism, recurrent laryngeal nerve palsy and bleeding requiring reoperation occurred in 170 (26·2 per cent), 62 (13·7 per cent) and 17 (2·6 per cent) patients respectively.
D.‐J. van Beek   +18 more
wiley   +1 more source

Single‐Cell RNA Sequencing of Thyroid Tissues Reveals Pathogenesis of Graves' Disease

open access: yesAdvanced Science, EarlyView.
Using single‐cell RNA sequencing and TCR profiling, this study constructed an immune cell atlas in thyroid tissue of Graves’ disease (GD), revealing dominant IFN‐γ‐secreting CD4+ T cells, expanded Tph and CD11c+ B cells, and enriched T/NK cells. Notably, GD thyroid follicular cells (TFCs) activated γδ T cells, which recruited cDC1 cells, suggesting a ...
Xiaoyi Zhou   +18 more
wiley   +1 more source

TSH Ligand‐Based CAR‐T Cell Effectively Eradicates TSHR‐Positive Thyroid Cancer with Favorable Safety Profile

open access: yesAdvanced Science, EarlyView.
TSHR is highly expressed in differentiated thyroid cancer (DTC), making it an ideal target for adoptive immune cell therapy. A novel Ligand‐based TSH‐CAR‐T cell approach effectively eradicated TSHR‐positive thyroid tumors in vitro and accomplished full remission in tumor models with favorable safety profile, highlighting that TSH‐CAR‐T cells could ...
Fei Wang   +10 more
wiley   +1 more source

Performance of Two‐Tiered Subclassification of Atypia of Undetermined Significance in Thyroid Fine‐Needle Aspiration Without Routine Molecular Testing

open access: yesDiagnostic Cytopathology, EarlyView.
ABSTRACT Background The third edition of the Bethesda system for reporting thyroid cytopathology recommends a simplified two‐tiered subclassification of atypia of undetermined significance (AUS), dividing cases into AUS with nuclear atypia (AUS‐Nuclear) and other atypia (AUS‐Other).
Pocholo D. Santos   +2 more
wiley   +1 more source

Association Between Annual Surgeon Total Thyroidectomy Volume and Transient and Permanent Complications.

open access: yesJAMA Otolaryngology - Head and Neck Surgery, 2019
Importance Although the association between annual surgeon total thyroidectomy volume and clinical outcomes is well established, published methods typically group surgeons into volume categories.
Charles J Meltzer   +3 more
semanticscholar   +1 more source

Partial Laryngectomy for Thyroid Cancer: A Single Institution Case Series With Operative Techniques

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Partial laryngectomy has been well described as a management option for T1–3 laryngeal squamous cell cancers. However, there are a few case reports of partial laryngeal surgery for locally advanced thyroid carcinoma. Methods This is a case series of five patients with thyroid carcinoma (one primary and four recurrent) with laryngeal
Ella E. Hawes   +17 more
wiley   +1 more source

Transoral Vestibular Thyroidectomy: Current State of Affairs and Considerations for the Future.

open access: yesJournal of Clinical Endocrinology and Metabolism, 2019
CONTEXT The transoral endoscopic thyroidectomy vestibular approach (TOETVA) is a recently described procedure for surgical management of select thyroid pathology without the need for a cutaneous scar.
J. Russell   +6 more
semanticscholar   +1 more source

Prognostic Significance of Solid Subtype of Papillary Thyroid Carcinoma: Analysis of 63 Patients

open access: yesHead &Neck, EarlyView.
ABSTRACT Objective Solid subtype of papillary thyroid carcinoma (SSPTC) is an uncommon subtype of papillary thyroid cancer (PTC) and its prognostic significance is still controversial. The aim of this review is to present the clinicopathological features of SSPTC and compare its clinical behavior with classical PTC (cPTC).
Andre Ywata de Carvalho   +3 more
wiley   +1 more source

Thyroid Volume Measurement With AI‐Assisted Freehand 3D Ultrasound Compared to 2D Ultrasound—A Clinical Trial

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Accurate thyroid volume assessment is critical in thyroid disease diagnostics, yet conventional high‐resolution 2D ultrasound has limitations. Freehand 3D ultrasound with AI‐assisted segmentation presents a potential advancement, but its clinical accuracy requires validation.
Klara Bay Rask   +4 more
wiley   +1 more source

Comparison between total thyroidectomy and medical therapy for amiodarone-induced thyrotoxicosis.

open access: yesJournal of Clinical Endocrinology and Metabolism, 2019
CONTEXT It is not known whether total thyroidectomy is more favourable than medical therapy for patients with amiodarone-induced thyrotoxicosis (AIT). OBJECTIVE To compare total thyroidectomy with medical therapy on survival and cardiac function in AIT
D. Cappellani   +16 more
semanticscholar   +1 more source

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