Results 41 to 50 of about 60,233 (265)

Thyroid Hemiagenesis Associated with Hashimoto’s Thyroiditis [PDF]

Case Reports in Endocrinology, 2013
Thyroid hemiagenesis is a rare congenital anomaly resulting from failure of one thyroid lobe development. We report a 23-year-old female presented with Hashimoto’s thyroiditis in left lobe, associated with hemiagenesis of right lobe and isthmus which was previously diagnosed as Graves’ hyperthyroidism, but developed further into Hashimoto’s thyroiditis
D. Nsame, A. Chadli, L. Hallab, S. El Aziz, H. El Ghomari, A. Farouqi   +5 more
openaire   +3 more sources

Autoimmune Comorbidities as Modifiers of Phenotypic Heterogeneity in Facioscapulohumeral Dystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral dystrophy type 1 (FSHD1) shows clinical heterogeneity that is only partly explained by D4Z4 repeat unit (RU) size. Although immune and inflammatory mechanisms may contribute to disease variability, the prevalence and clinical impact of autoimmune diseases in FSHD remain unclear.
Jonathan Pini, Giulia Tammam, Andra Ezaru, Manuela Gambella, Benoît Sanson, Luisa Villa, Michele Cavalli, Mihai‐Bogdan Ioncea, Angela Puma, Sabrina Sacconi   +9 more
wiley   +1 more source

An unusual presentation of longstanding atrophic Hashimoto’s thyroiditis: challenges in a resource-limited setting

Endocrinology, Diabetes & Metabolism Case Reports
Hypothyroidism, affecting approximately 5% of the population, often remains undiagnosed, more so in developing countries. We report a 12-year-old girl with longstanding, untreated hypothyroidism who initially presented with proteinuria.
Phoebe Wamalwa, Prisca Amolo
doaj   +1 more source

From Interferon Signature to the Clinical Landscape: Type I Interferonopathies

Arthritis &Rheumatology, EarlyView.
Objective TypeI interferonopathies are heterogeneous diseases driven by dysregulated type I interferon (IFN‐I) signaling. Diagnosis is challenging due to clinical/molecular variability and the need for IFN‐I quantification. The aim of this study was to characterize the clinical, immunologic, genetic, molecular profiles of patients with suspected ...
Ismail Yaz, Seza Ozen, Hacer Neslihan Bildik, Canberk Ipsir, Dilara Unal, Saliha Esenboga, Begum Cicek, Mehmet Emin Seker, Fatima Aerts‐Kaya, Seher Sener, Mehmet Orhan Erkan, Hanife Avci, Deniz Cagdas, Ilhan Tezcan   +13 more
wiley   +1 more source

Thyroiditis

, 2011
Thyroiditis comprises a diverse group of disorders that are among the most common endocrine abnormalities encountered in clinical practice. These disorders range from the extremely common chronic lymphocytic thyroiditis (Hashimoto’s thyroiditis) to the ...
Beth Kaplan, Elizabeth N. Pearce, Alan P. Farwell   +2 more
core   +1 more source

Lithium‐related adverse drug reactions in children: A case–control study comparing lithium to second‐generation antipsychotics in VigiBase

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to improve the understanding of lithium's safety profile by analysing the frequency and distribution of reported adverse drug reactions (ADRs) compared to second‐generation antipsychotics (SGAs). Methods Individual case safety reports from VigiBase (1968–October 2023) involving individuals older than 2 years, with lithium or SGAs ...
Lisa T. Ringeling, Ravish N. Gangapersad, Lillian Lieuw, Patrick C. Souverein, Eibert R. Heerdink, Pilar Garcia‐Gomez, Manon H. J. Hillegers, Birgit C. P. Koch, Bram Dierckx   +8 more
wiley   +1 more source

A case of immunotherapy-induced thyroiditis

Exploration of Targeted Anti-tumor Therapy
Immunotherapy treatments for cancer are known to cause adverse thyroid events which present a diagnostic challenge to clinicians and radiologists. This case report highlights the importance of a high clinical index of suspicion and careful assessment of ...
George Pears, Abhishek Mahajan, Anna Olsson-Brown, Joseph Sacco   +3 more
doaj   +1 more source

Bilateral Symmetry and Variation of Recurrent Laryngeal Nerve and Inferior Thyroid Artery Patterns: An Intraoperative Study of 150 Nerves

Clinical Anatomy, EarlyView.
ABSTRACT The anatomical relationship of the inferior thyroid artery (ITA) and the recurrent laryngeal nerve (RLN) is highly variable. This study aims to evaluate bilateral RLN branching patterns and their relationship to the ITA within the same patient, predicting contralateral anatomical variations and ultimately reducing intraoperative risk of RLN ...
Mark Yanni, Stavroula Mouratidou, Aleix Rovira, Ricard Simo   +3 more
wiley   +1 more source

Thyroid dysfunction in hepatitis C individuals treated with interferon-alpha and ribavirin: a review

Brazilian Journal of Infectious Diseases
Hepatitis C (HCV) is now the main cause of chronic hepatic disease, cirrhosis and hepatocellular carcinoma. Several extrahepatic diseases have been associated with chronic HCV infection, and in most cases appear to be directly related to the viral ...
Luis Jesuíno de Oliveira Andrade, Ajax Mercês Atta, Argemiro D'Almeida Junior, Raymundo Paraná   +3 more
doaj   +1 more source

p53 Activation Effect in the Balance of T Regulatory and Effector Cell Subsets in Patients With Thyroid Cancer and Autoimmunity

Frontiers in Immunology, 2021
Carcinomas evade the host immune system by negatively modulating CD4+ and CD8+ T effector lymphocytes through forkhead box protein 3 (FOXP3) positive T regulatory cells’ increased activity.
Andrea Arena, Antonio Stigliano, Eugenia Belcastro, Ezio Giorda, Maria Manuela Rosado, Maria Manuela Rosado, Armando Grossi, Maria Rita Assenza, Fabiola Moretti, Alessandra Fierabracci   +9 more
doaj   +1 more source