Results 31 to 40 of about 24,772 (224)

Ashwagandha: Is It Safe? Part 2: A Preclinical Evidence Review

Phytotherapy Research, EarlyView.
ABSTRACT The preclinical evidence for the safety of ashwagandha (Withania somnifera (L.) Dunal, AS) is reviewed, and its preparations (extracts) and constituents, from the general toxicity in animal models to in vitro and cell culture studies, which may elucidate mechanisms of action and explain clinical case reports.
Elizabeth M. Williamson, Thomas Brendler
wiley   +1 more source

Anaesthetic Management of a Patient with Thyrotoxicosis for Nonthyroid Surgery with Peripheral Nerve Blockade

Case Reports in Anesthesiology, 2016
Thyrotoxicosis is a hypermetabolic condition caused by an elevation in thyroid hormone levels. The disorder has a variety of causes, manifestations, and therapies.
Mehmet I. Buget, Bilge Sencan, Giray Varansu, Suleyman Kucukay   +3 more
doaj   +1 more source

Ultrastructural liver changes in the experimental thyrotoxicosis

Polish Journal of Pathology, 2017
Aim of the study is to evaluate ultrastructural changes of rat liver in experimental thyrotoxicosis. For the study, 36 male rats have been utilized, weighing approximately 150-190 g, which were divided into three groups: the first, control group (12 ...
Nadiya Vasylivna Pasyechko, Iryna Ihorivna Kuleshko, Veronika Mykolaiivna Kulchinska, Liudmyla Valeriivna Naumova, Iryna Volodymyrivna Smachylo, Anzhela Olehivna Bob, Liudmyla Volodymyrivna Radetska, Mykhailo Yevhenovych Havryliuk, Olha Mykolaiivna Sopel, Liudmyla Petrivna Mazur   +9 more
doaj   +1 more source

Ashwagandha: Is It Safe? Part 1: A Regulatory Review

Phytotherapy Research, EarlyView.
ABSTRACT Over the last decade, ashwagandha (Withania somnifera (L.) Dunal, AS) has been brought under increasing scrutiny by EU regulators regarding its safety for the use in food supplements, culminating in a recent recommendation for an Article 8 procedure according to Regulation (EC) No. 1925/2006 in the European Union (EU).
T. Brendler, R. Al‐Mondhiry, L. Lang, R. Marles, M. Tallon, A. Raghu   +5 more
wiley   +1 more source

Transient non rate related left bundle branch block in thyrotoxicosis: A case report

Proceedings of Singapore Healthcare
Thyrotoxicosis is a common condition that is associated with cardiovascular complications. The most common complications that occurs are heart failure and cardiac arrhythmias. Cardiac arrhythmias due to thyrotoxicosis negatively affect the cardiovascular
Nur Izat Muhamad, Rajiv Subramaniam, Mohd Khairi Othman, Zurkurnai Yusof, Wan Izani Wan Mohamed, W Yus Hanif W Isa   +5 more
doaj   +1 more source

Anesthetic Maintenance of Thyroid Surgery

Общая реаниматология, 2008
Thyroid diseases are most common in endocrinology. Thyrotoxicosis induces dysfunction of virtually all organs and systems, the blood circulatory system being subjected to considerable changes.
A. A. Negovsky, T. I. Shpazhnikova, A. A. Znamensky, M. N. Zamyatin   +3 more
doaj   +1 more source

Evaluation of Potential Hormonal Activities of Ashwagandha (Withania somnifera)

Phytotherapy Research, EarlyView.
ABSTRACT Ashwagandha is a widely used herb in traditional medicine systems, particularly Ayurveda. Despite its extensive tradition, growing concerns regarding its potential endocrinological effects have prompted scientific scrutiny. This review systematically evaluates the current preclinical, clinical, and case study evidence concerning AS's effects ...
Günter Vollmer, Thomas Brendler
wiley   +1 more source

Thyrotoxicosis. Clinical recommendations for diagnosis and treatment Part І

Український радіологічний та онкологічний журнал, 2020
Background. Currently submitted an increased rate of thyrotoxicosis, which is characterized by polyetiology, a variety of clinical manifestations and potential treatments.
Н. С. Підченко
doaj   +1 more source

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

British Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen, Tamás Kovács, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source

Evaluating the Link Between Thyroid Function Test Results and Levothyroxine Dose in the Management of Hypothyroidism: Can We Improve Dosing Regimes?

Clinical Endocrinology, EarlyView.
ABSTRACT Introduction Over 10 million thyroid function tests (TFTs) are carried out in England each year, most requests coming from primary care. Our previous work showed that only 25% of results for patients being treated with Levothyroxine fell within the TSH/FT4 boundary circumscribing 75% of untreated individuals.
Adrian H. Heald, Lakdasa D. Premawardhana, Peter N. Taylor, Suhani Bahl, Onyebuchi E. Okosieme, Anthony A. Fryer, Antonio Bianco, Colin M. Dayan, Michael P. Stedman   +8 more
wiley   +1 more source