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A subtle initial clinical presentation of a TSH-secreting PitNET. [PDF]

open access: yesEndocrinol Diabetes Metab Case Rep
Buè R, Gianola L, Trimboli P.
europepmc   +1 more source
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Thyrotropin binding specificity for the thyrotropin receptor

Journal of Endocrinological Investigation, 1995
Recently, highly purified bovine thyrotropin (bTSH) of pituitary origin, as well as recombinant human (h) TSH free of lutropin (LH) contamination, has been reported to activate the LH/choriogonadotropin receptor (LH/CGR). These data challenge the concept of TSH specificity for its own receptor.
Y, Nagayama   +8 more
openaire   +2 more sources

Thyrotropin receptor processing and interaction with thyrotropin

Biochemical and Biophysical Research Communications, 1990
In vitro transcription/translation, using rat thyrotropin receptor cDNA, results in the formation of nonglycosylated proteins able to bind thyrotropin, one of which approximates the 87 Kd size predicted for the receptor. In the presence of canine pancreatic microsomal membranes, putative glycosylation sites are modified as evidenced by digestion with ...
T, Akamizu, S, Kosugi, L D, Kohn
openaire   +2 more sources

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