Results 301 to 310 of about 66,698 (357)
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Thyrotropin Pituitary Adenomas
World Neurosurgery, 2014irkman et al., by reporting on their experience at National Hospital for Neurology and Neurosurgery of London K with thyrotropin (TSH)-expressing pituitary adenomas, have contributed an important and welcomed addition to the literature about pituitary tumors.
Michelangelo, de Angelis +1 more
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New England Journal of Medicine, 1982
The modern era of neuroendocrinology was ushered in just over a decade ago with the isolation and characterization, from ovine1 and porcine2 hypothalamic tissue, of a tripeptide (pyroglutamyl-histi...
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The modern era of neuroendocrinology was ushered in just over a decade ago with the isolation and characterization, from ovine1 and porcine2 hypothalamic tissue, of a tripeptide (pyroglutamyl-histi...
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Thyrotropin and Thyrotropin-Releasing Hormone
1987Pituitary thyrotropin, or thyroid-stimulating hormone (TSH), as the name implies, is the principal regulator that governs the growth and function of the thyroid gland. The secretion, metabolism, regulatory control, and actions of this important glycoprotein form the basis of this chapter.
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Thyroid, 2017
Macro-thyrotropin (TSH) is a high-molecular-weight form of TSH. Most cases of macro-TSH are TSH complexed with immunoglobulin G. This study was undertaken to characterize macro-TSH.Blood samples taken from patients with subclinical hypothyroidism were screened for the presence of macro-TSH with the polyethylene glycol method and confirmed with gel ...
Naoki, Hattori +4 more
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Macro-thyrotropin (TSH) is a high-molecular-weight form of TSH. Most cases of macro-TSH are TSH complexed with immunoglobulin G. This study was undertaken to characterize macro-TSH.Blood samples taken from patients with subclinical hypothyroidism were screened for the presence of macro-TSH with the polyethylene glycol method and confirmed with gel ...
Naoki, Hattori +4 more
openaire +2 more sources
Thyroid, 1999
Thyrotropin receptor autoantibodies (TRAb) are most commonly measured in a thyrotropin-binding inhibition (TBI) assay using solubilized porcine thyrotropin receptors (pTSHR). Recently, we reported modifications in recombinant human thyrotropin receptor (hTSHR) production and extraction that made substitution of this antigen for the pTSHR practical.
A, Kakinuma +6 more
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Thyrotropin receptor autoantibodies (TRAb) are most commonly measured in a thyrotropin-binding inhibition (TBI) assay using solubilized porcine thyrotropin receptors (pTSHR). Recently, we reported modifications in recombinant human thyrotropin receptor (hTSHR) production and extraction that made substitution of this antigen for the pTSHR practical.
A, Kakinuma +6 more
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1995
This chapter has outlined the complex process required for thyroid growth and function. Both events are regulated by TSHR via a multiplicity of signals, with the aid of and requirement for a multiplicity of hormones that regulate the TSHR via receptor cross-talk: insulin, IGF-I, adrenergic receptors, and purinergic receptors.
L. D. Kohn +8 more
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This chapter has outlined the complex process required for thyroid growth and function. Both events are regulated by TSHR via a multiplicity of signals, with the aid of and requirement for a multiplicity of hormones that regulate the TSHR via receptor cross-talk: insulin, IGF-I, adrenergic receptors, and purinergic receptors.
L. D. Kohn +8 more
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POSITIVE REGULATION OF HUMAN THYROTROPIN RECEPTOR mRNA BY THYROTROPIN
The Journal of Clinical Endocrinology & Metabolism, 1991We have assessed the influence of natural and recombinant thyrotropin (TSH) on mRNA specific for the human TSH receptor (TSHR) in normal and abnormal adult human thyroid monolayer cells. Using physiological concentrations of TSH (less than 100 mU/L), a marked increase in the level of TSHR mRNA was observed within 12 hours and reached a greater than ...
G K, Huber +3 more
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Journal of Endocrinological Investigation, 2003
Resistance to TSH is a syndrome of reduced sensitivity to a biologically active TSH molecule. Subjects have elevated TSH levels but no goiter. However, thyroid hormone concentration may vary from normal to very high, depending on the severity of the resistance.
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Resistance to TSH is a syndrome of reduced sensitivity to a biologically active TSH molecule. Subjects have elevated TSH levels but no goiter. However, thyroid hormone concentration may vary from normal to very high, depending on the severity of the resistance.
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Hypothalamic Thyrotropin-Releasing Hormone and Thyrotropin Biological Activity
Thyroid, 1998Hypothalamic thyrotropin-releasing hormone (TRH) is the main positive regulator of thyrotropin (TSH) secretion. TRH action and the negative feedback of thyroid hormone are integrated in order to guarantee appropriate thyroid stimulation. TRH action affects various steps of the biosynthetic process within thyrotrophs, with major effects on the ...
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Binding of thyrotropin releasing hormone by thyrotropin-secreting cells
Biochemical and Biophysical Research Communications, 1973Abstract In order to localize and identify receptor structures, the binding of radiolabeled thyrotropin releasing hormone (TRH) to thyrotropin (TSH)-secreting cells from rat and bovine anterior pituitaries and from a mouse TSH-secreting tumor was studied in vitro . The binding of TRH to rat anterior pituitaries increased linearly with the log of
Eddy, L J +3 more
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