Results 181 to 190 of about 106,006 (259)

Selenoprotein H Functions as a PPARα Coactivator to Link Selenium Homeostasis to Hepatic Lipid Metabolism and Protect against Steatohepatitis

open access: yesAdvanced Science, Volume 13, Issue 22, 17 April 2026.
Our study identifies selenium deficiency as a hallmark of MASH pathogenesis. Dietary selenium supplementation enhances hepatic fatty acid oxidation (FAO) and attenuates MASH progression by activating the PPARα pathway via selenoprotein H (SELENOH). This selenium‐SELENOH‐PPARα nexus redefines the functional scope of selenoproteins, moving from redox ...
Yuwei Zhang   +11 more
wiley   +1 more source

Thyroxine in goiter, Helicobacter pylori infection, and chronic gastritis.

open access: yesNew England Journal of Medicine, 2006
M. Centanni   +6 more
semanticscholar   +1 more source

A “Hot Spring” Mimetic Aerogel Loaded with Multiple Amino Acids Modulates the Chronic Inflammatory Microenvironment Through Metabolic Reprogramming

open access: yesAdvanced Science, Volume 13, Issue 20, 9 April 2026.
The SrCuSi4O₁₀ bioceramic particles mimic the effects of hot spring therapy by increasing the local wound temperature, which enhances the absorption of amino acids and stimulates cell metabolism. The amino acid uptake supports cellular glutathione redox reactions, helping to mitigate oxidative stress.
Bo Li   +7 more
wiley   +1 more source

Methods for Improving Settlement and Metamorphosis of Shelled Marine Mollusks in Aquaculture: A Review

open access: yesAquaculture, Fish and Fisheries, Volume 6, Issue 2, April 2026.
Settlement and metamorphosis are key developmental hurdles in marine mollusk aquaculture. Environmental signals (such as biofilms, algae, and signals from conspecifics) and biochemical pathways (including nitric oxide, thyroid hormones, catecholamines, and GABA) regulate the transition of larvae into benthic juveniles. Combining ecological observations
Angelica R. Valdez   +2 more
wiley   +1 more source

Risk of cardiac, neuropsychiatric and musculoskeletal adverse events with levothyroxine: Systematic review

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 4, Page 1023-1039, April 2026.
Abstract Levothyroxine (LT4) is the standard treatment for hypothyroidism and the most widely prescribed medication worldwide. Although generally safe, regulatory reports list potential cardiac, neuropsychiatric and musculoskeletal adverse events (AEs). Clarifying their clinical relevance is essential.
Bala Swetha Baskaran   +2 more
wiley   +1 more source

Mapping molluscan endocrinology: a systematic and critical appraisal

open access: yesBiological Reviews, Volume 101, Issue 2, Page 970-1002, April 2026.
ABSTRACT Historically, a vertebrate‐centric paradigm has framed our interpretation of molluscan endocrinology, with considerable research focusing on vertebrate‐type steroid hormones (e.g. oestrogens, testosterone). However, contradictory evidence on the occurrence of vertebrate‐type steroid hormones in molluscan tissues, and a lack of the specific ...
Konstantinos Panagiotidis   +3 more
wiley   +1 more source

Immune‐Related Adverse Events in Bladder Cancer Patients Treated With Immune Checkpoint Inhibitors: Insights From a FAERS Disproportionality Analysis

open access: yesCancer Medicine, Volume 15, Issue 4, April 2026.
ABSTRACT Introduction Immune checkpoint inhibitors (ICIs) are an important treatment option in bladder cancer, but clinical trials have demonstrated that they are associated with immune‐related adverse events (irAEs), such as rash, hypothyroidism, hyperthyroidism, and others. This study aimed to evaluate real‐world evidence of these irAEs using the FDA
Pooja Gokhale, Lorenzo Villa Zapata
wiley   +1 more source

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