Results 271 to 280 of about 108,632 (316)
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Thyroxine alone or thyroxine plus triiodothyronine replacement therapy for hypothyroidism.
Nuclear medicine communications, 2009Standard therapy for patients with hypothyroidism is replacement with synthetic thyroxine (T4). However, thyroxine plus triiodothyronine (T3) replacement therapy resulted in marked improvements in several items of the Profile of Mood States and in a few ...
Chao Ma +6 more
semanticscholar +2 more sources
Clinical Endocrinology, 1974
SUMMARYThe effective thyroxine ratio (ETR), a single test of thyroid function which has a highly significant linear correlation with serum free thyroxine (T4) concentration, was assessed for its effectiveness in distinguishing the euthyroid state in subjects with abnormalities of T4‐binding proteins.In patients with low activity of T4‐binding proteins,
M.L. Wellby +2 more
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SUMMARYThe effective thyroxine ratio (ETR), a single test of thyroid function which has a highly significant linear correlation with serum free thyroxine (T4) concentration, was assessed for its effectiveness in distinguishing the euthyroid state in subjects with abnormalities of T4‐binding proteins.In patients with low activity of T4‐binding proteins,
M.L. Wellby +2 more
openaire +3 more sources
Biochemistry, 2010
Amyloid fibril formation is associated with protein misfolding disorders, including neurodegenerative diseases such as Alzheimer's, Parkinson's, and Huntington's diseases.
M. Miyata +19 more
semanticscholar +1 more source
Amyloid fibril formation is associated with protein misfolding disorders, including neurodegenerative diseases such as Alzheimer's, Parkinson's, and Huntington's diseases.
M. Miyata +19 more
semanticscholar +1 more source
European Journal of Nuclear Medicine, 1983
Free T4 calculation was performed based on the equation of the law of mass action between T4 and TBG assessed by routine radioimmunoassay. To examine the validity of this calculation, sera from normal subjects, from hypo- and hyperthyroid patients, from subjects with hereditary deficiency or increase in TBG, and those from uncomplicated pregnancy were ...
Natsuko Ohtsuki +2 more
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Free T4 calculation was performed based on the equation of the law of mass action between T4 and TBG assessed by routine radioimmunoassay. To examine the validity of this calculation, sera from normal subjects, from hypo- and hyperthyroid patients, from subjects with hereditary deficiency or increase in TBG, and those from uncomplicated pregnancy were ...
Natsuko Ohtsuki +2 more
openaire +3 more sources
Thyroxine-protein interactions
Biochimica et Biophysica Acta (BBA) - Protein Structure, 1978The binding constants for interaction of various thryoxine analogues with the thyroxine binding site on human thyroxine-binding globulin have been determined. Equilibrium dialysis, at pH 7.4 and 37 degrees C, was used to measure the competitive effects of different iodothyronine compounds on the binding of 125I-labeled thyroxine to highly purified ...
Ladislav Korcek, Milton Tabachnick
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Endocrinology, 1979
GH1 cells are a clonal strain of rat pituitary tumor cells which synthesize GH and PRL. We have previously demonstrated that these cells respond to physiological concentrations of L-T3 and L-T4 when cultured with medium supplemented with thyroidectomized
H. Samuels, F. Stanley, J. Casanova
semanticscholar +1 more source
GH1 cells are a clonal strain of rat pituitary tumor cells which synthesize GH and PRL. We have previously demonstrated that these cells respond to physiological concentrations of L-T3 and L-T4 when cultured with medium supplemented with thyroidectomized
H. Samuels, F. Stanley, J. Casanova
semanticscholar +1 more source
The Journal of Clinical Endocrinology & Metabolism, 1971
ABSTRACT Studies were conducted concerning the relation between TT4 and AFT4 in a family with TBG deficiency, consisting of 8 affected and 16 unaffected members, and in a group of 48 normals. A highly significant positive relationship between these 2 parameters was found within the family, as well as within the group of normals.
G. Hennemann, Roelof Docter, A. Dolman
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ABSTRACT Studies were conducted concerning the relation between TT4 and AFT4 in a family with TBG deficiency, consisting of 8 affected and 16 unaffected members, and in a group of 48 normals. A highly significant positive relationship between these 2 parameters was found within the family, as well as within the group of normals.
G. Hennemann, Roelof Docter, A. Dolman
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European Journal of Endocrinology, 1994
L-Thyroxine (L-T4) in the treatment of thyroid disease resulting in reduced serum thyrotropin (TSH) has been associated with reduced bone mass and thus the potential risk of premature development of osteoporosis.
J. Faber, A. Galløe
semanticscholar +1 more source
L-Thyroxine (L-T4) in the treatment of thyroid disease resulting in reduced serum thyrotropin (TSH) has been associated with reduced bone mass and thus the potential risk of premature development of osteoporosis.
J. Faber, A. Galløe
semanticscholar +1 more source
Thyroxine binding and deiodination of thyroxine by human lymphocytes
Clinica Chimica Acta, 1978Binding and deiodination of T4 by lymphocytes from euthyroid, hypothyroid and hyperthyroid subjects were studied. Two sets of binding sites were found on normal lymphocytes. One set with equilibrium association constant of 6.9 X 10(9) l/mol and a maximal binding capacity of 3000 mol T4 per lymphocyte, and another set with equilibrium association ...
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Studies on thyroxine-binding globulin
Biochimica et Biophysica Acta (BBA) - Protein Structure, 1972Abstract 1. 1.|The quenching of thyroxine-binding globulin intrinsic protein fluorescence by ligands was used to demonstrate the binding of 0.85 ± 0.06 mole of thyroxine per mole of purified thyroxine-binding globulin and 0.91 ± 0.06 mole of triiodothyronine per mole of thyroxine-binding globulin. 2.
James S. Marshall +7 more
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