Impact of Direct Oral Anticoagulant Uptake on Hospitalizations for Stroke/Transient Ischemic Attack, Intracranial Hemorrhage, and Gastrointestinal Bleeding in Individuals With Atrial Fibrillation: A Population-Based Study. [PDF]
ABSTRACT Background Direct‐acting oral anticoagulants (DOACs) have largely replaced warfarin for stroke prevention in patients with atrial fibrillation, yet their population‐level impact on health outcomes and costs remains unclear. We examined whether the widespread uptake of DOACs was associated with changes in hospitalization rates and costs for ...
Antoniou T +4 more
europepmc +2 more sources
Periodontitis and atherosclerotic cardiovascular disease: A critical appraisal
Abstract In spite of intensive research efforts driving spectacular advances in terms of prevention and treatments, cardiovascular diseases (CVDs) remain a leading health burden, accounting for 32% of all deaths (World Health Organization. “Cardiovascular Diseases (CVDs).” WHO, February 1, 2017, https://www.who.int/news‐room/fact‐sheets/detail ...
Maria Clotilde Carra +3 more
wiley +1 more source
Assessing the causal effect of genetically predicted metabolites and metabolic pathways on stroke
Background Stroke is a common neurological disorder that disproportionately affects middle-aged and elderly individuals, leading to significant disability and mortality.
Tianlong Zhang +4 more
doaj +1 more source
Observation of the TeV gamma-ray source MGRO J1908+06 with ARGO-YBJ [PDF]
The extended gamma ray source MGRO J1908+06, discovered by the Milagro air shower detector in 2007, has been observed for about 4 years by the ARGO-YBJ experiment at TeV energies, with a statistical significance of 6.2 standard deviations.
00133 Roma +215 more
core +3 more sources
Effect of allopurinol on phosphocreatine recovery and muscle function in older people with impaired physical function:a randomised controlled trial [PDF]
Background: Allopurinol has vascular antioxidant effects and participates in purinergic signalling within muscle. We tested whether allopurinol could improve skeletal muscle energetics and physical function in older people with impaired physical ...
Cavin, Ian +10 more
core +2 more sources
Investigations of fast neutron production by 190 GeV/c muon interactions on different targets [PDF]
The production of fast neutrons (1 MeV - 1 GeV) in high energy muon-nucleus interactions is poorly understood, yet it is fundamental to the understanding of the background in many underground experiments. The aim of the present experiment (CERN NA55) was
Boehm, F. +8 more
core +2 more sources
Olivier Chesneau's work on massive stars [PDF]
Olivier Chesneau challenged several fields of observational stellar astrophysics with bright ideas and an impressive amount of work to make them real in the span of his career, from his first paper on P Cygni in 2000, up to his last one on V838 Mon in ...
Millour, Florentin
core +4 more sources
Statistical emulation of a tsunami model for sensitivity analysis and uncertainty quantification [PDF]
Due to the catastrophic consequences of tsunamis, early warnings need to be issued quickly in order to mitigate the hazard. Additionally, there is a need to represent the uncertainty in the predictions of tsunami characteristics corresponding to the ...
Dias, F., Guillas, S., Sarri, A.
core +2 more sources
Route diversity analyses for free-space optical wireless links within turbulent scenarios [PDF]
Free-Space Optical (FSO) communications link performance is highly affected when propagating through the time-spatially variable turbulent environment.
Anguita +29 more
core +2 more sources
Delayed mortality effects cut the malaria transmission potential of insecticide resistant mosquitoes [PDF]
Malaria transmission has been substantially reduced across Africa through the distribution of long-lasting insecticidal nets (LLINs). However, the emergence of insecticide resistance within mosquito vectors risks jeopardizing the future efficacy of this ...
Ferguson, Heather M. +4 more
core +3 more sources

