Results 31 to 40 of about 69,003 (282)

Targeted Restoration of the Microbial Tryptophan Oxidative Pathway Ameliorates Autism‐Like Behavioral and Synaptic Deficits

open access: yesAdvanced Science, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo   +14 more
wiley   +1 more source

Gut Microbial Release of Ferulic Acid From Germinated Quinoa Alleviates Obesity‐Associated Cognitive Impairment by Activating Hippocampal Mitophagy Associated with PINK1/Parkin Pathway

open access: yesAdvanced Science, EarlyView.
Liberation of ferulic acid by gut microbial feruloyl esterase mediates cognitive enhancement of germinated quinoa (GQF) on obese mice. Ferulic acid enriched in GQF is released by gut microbes Roseburia hominis and R. intestinalis and subsequently mediates the neuroprotective effects of GQF on obesity‐induced cognitive decline by activating hippocampal ...
Yongli Lan   +11 more
wiley   +1 more source

Mahayana Philosophy: Problems and Research

open access: yesRUDN Journal of Philosophy
The introduction to the topic of this issue is an overview of the research articles authored by Russian, Lithuanian, and Indian scholars on various problems of Mahayana Buddhist philosophy.
Victoria G. Lysenko
doaj   +1 more source

The Annals of Kokonor by Sum pa mkhan po Ye shes dpal ‘byor Revisited

open access: yesOriental Studies, 2021
Goals. The article provides a historiography of studies dealing with the famous TibetoMongolian scholar Sum pa mkhan po Ye shes dpal ‘byor, introduces one of his important works — The Annals of Kokonor — and presents a translation of its first chapter ...
Irina R. Garri, Yumzhana Zh. Zhabon
doaj   +1 more source

Transposable Element–Driven PIEZO Mutation Enhances Locust Flight in Plateau Hypoxia

open access: yesAdvanced Science, EarlyView.
Why transposable elements (TEs) persisted or expanded in genomes remains a mystery. Using integrated analysis of TE macro‐ and microevolution in locusts, our results showed that thousands of TE insertions promoted widespread adaptive variation. Subfamilies of candidate adaptive TEs amplified and reshaped species‐level genomic architecture.
Xuanzhao Li   +8 more
wiley   +1 more source

Mineral and bone disorder in hemodialysis patients in the Tibetan Plateau: a multicenter cross-sectional study

open access: yesRenal Failure, 2019
Background: Mineral and bone disorder (MBD) in hemodialysis patients is associated with increased morbidity and mortality. Studies on the MBD status of hemodialysis patients at high altitudes are extremely limited.
Zong-Hui Dang   +8 more
doaj   +1 more source

Cladistic analysis of Sericania (Coleoptera: Scarabaeidae: Sericini) - implications for the evolution of the xerophilous fauna of the Himalaya

open access: yesEuropean Journal of Entomology, 2007
A cladistic analysis of the species of Sericania Motschulsky, 1860, was executed using fifty-six morphological characters of adults. The monophyly of the genus is supported by the phylogenetic trees generated.
Dirk AHRENS
doaj   +1 more source

Groundwater Rise Sustains the World's Largest Alpine Water System Under Global Warming

open access: yesAdvanced Science, EarlyView.
Shallow groundwater depth (SGWD) across the non‐permafrost plains of the Qinghai–Xizang Plateau decreased at averagely 0.02 m year−1, adding 31.44 Gt of freshwater storage from 2000 to 2020 and sustaining ∼53 500 km2 of alpine ecosystems. A vadose‐zone capacity of 426.6 Gt reveals these aquifers as promising reservoirs, highlighting groundwater's ...
Jianqing Du   +15 more
wiley   +1 more source

Colonel Younghusband's mission to Lhasa 1904: parliament, the British government and the 'forward policy' in Tibet [PDF]

open access: yes, 1989
This thesis takes as its focus the Mission led by Colonel Younghusband in 1904 and despatched to Lhasa by the Viceroy of India, Lord Curzon; and places it in the context of British suspicion of Russia's ambitions in Central Asia at the close of the ...
Hull, A.M.A.
core  

Temperature‐Modulated MEMS Gas Sensor Array Enabled by Physics‐Informed Deep Learning for Thermal‐Runaway Characteristic Gas Discrimination

open access: yesAdvanced Science, EarlyView.
This work presents a 2 × 2 integrated single‐chip MEMS gas sensor array with temperature modulation and deep learning for discriminating thermal‐runaway characteristic gases. The array generates distinct temperature‐modulated response patterns for four characteristic gases (H2, CO, CH4, and CO2), while a HK‐MoE model is developed to achieve robust ...
Qin Luo   +8 more
wiley   +1 more source

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