Results 101 to 110 of about 35,546 (262)

The Mobility Politics of Hong Kong's High‐Speed Rail

Asia Pacific Viewpoint, EarlyView.
ABSTRACT Human geography scholarship has revealed how powerful and marginalised actors alike may use (im)mobility to exert authority, and it has recognised the ability of infrastructure to either consolidate or undermine state power. This paper uses new evidence to demonstrate how Hong Kong's express rail link (XRL) to Mainland China was implicated in ...
Benjamin Lucca Iaquinto
wiley   +1 more source

The L108I polymorphism in mouse prion protein drives spontaneous disease and enhances transmission of atypical and classical prion strains

Brain Pathology, EarlyView.
A single amino acid change (L108I) combined with PrP overexpression drives spontaneous atypical prion formation in mice, enabling also efficient propagation of diverse prion strains. This model allows studying how spontaneous prion diseases arise and provides powerful tools for investigating strain emergence, transmission barriers, and mechanisms ...
Hasier Eraña, Enric Vidal, Natalia Fernández‐Borges, Jorge M. Charco, Carlos M. Díaz‐Domínguez, Cristina Sampedro‐Torres‐Quevedo, Josu Galarza‐Ahumada, Eva Fernández‐Muñoz, Maitena San‐Juan‐Ansoleaga, Miguel Ángel Pérez‐Castro, Nuno Gonçalves‐Anjo, Patricia Piñeiro, Samanta Giler, Nora González‐Martín, Nuria L. Lorenzo, Africa Manero‐Azua, Guiomar Perez de Nanclares, Mariví Geijo, Manuel A. Sánchez‐Martín, Jesús R. Requena, Joaquín Castilla   +20 more
wiley   +1 more source

Songorine inhibits mitophagy in chronic heart failure via the TBC1D15/Fis1/Rab7A pathway

British Journal of Pharmacology, EarlyView.
Abstract Background and purpose Songorine (SGR) is an alkaloid extracted from Aconitum carichaelii Debx. and has a demonstrated role in cardiac dysfunction. Chronic heart failure (CHF) is a severe clinical syndrome leading to functional impairment and death, primarily due to the deterioration of energy metabolism in cardiomyocytes. However, the precise
Wenxiu Liu, Xingju Zou, Yang Zheng, Chen Sun, Cheng Peng   +4 more
wiley   +1 more source

Geographical features and management strategies for microplastic loads in freshwater lakes

npj Clean Water
In recent years, microplastic contamination in freshwater lakes has become a significant environmental concern. Despite this, there remains a lack of comprehensive understanding of the distribution patterns and regional characteristics of microplastic ...
Huike Dong, Ruixuan Zhang, Xiaoping Wang, Jiamin Zeng, Lei Chai, Xuerui Niu, Li Xu, Yunqiao Zhou, Ping Gong, Qianxue Yin   +9 more
doaj   +1 more source

Homo luzonensis and the role of homoplasy in the morphology of hominin insular species

Cladistics, EarlyView.
Abstract Homo luzonensis lived during the upper Pleistocene in the northern Philippines, east of the Wallace line. The few specimens attributed to this species show a mosaic of plesiomorphies for the genus Homo and apomorphies found in upper Pleistocene Homo species.
Pierre Gousset, Jérémie Bardin, Isabelle Rouget, Armand S. Mijares, Florent Détroit   +4 more
wiley   +1 more source

Effects of parachute science on local research capacity 降落伞科学对当地研究能力的影响

Conservation Biology, EarlyView.
Abstract Strengthening research capacity is essential to address the global biodiversity crisis. Yet, parachute science often undermines this goal, and its prevalence, costs, and benefits are unclear. We analyzed 13,502 publications on primate research that we extracted from Scopus (1960–2022) to evaluate the effects of parachute science on local ...
Li Yang, Tao Chen, Colin A. Chapman, Paul A. Garber, Yu Xuan Fan, Tien Ming Lee, Michael Huffman, Juan Carlos Serio Silva, Carlos Peres, Onja H. Razafindratsima, Lwin Ngwe, Peng Fei Fan   +11 more
wiley   +1 more source

Biodiversity‐driven spatial conservation planning to delineate temporally stable regions

Conservation Biology, EarlyView.
Abstract The accelerating loss of biodiversity underscores the critical need for effective conservation strategies, particularly in the face of climate change and anthropogenic pressures. We devised a conservation planning framework that adopts a temporal stacking approach to species distribution models and landscape connectivity analyses. These models
Mattia Iannella, Viviana Cittadino, Ilaria Bernabò, Antonio Romano, Maurizio Biondi, Davide Serva   +5 more
wiley   +1 more source

Cellular Signalling Networks in High Altitude Pulmonary Hypertension: From Canonical Pathways to Emerging Targets

Cell Proliferation, EarlyView.
This review elucidates the intricate cellular signalling networks involved in high‐altitude pulmonary hypertension (HAPH), integrating canonical pathways like HIF, MAPK and BMP with emerging targets such as Wnt/β‐catenin, Notch, Hippo‐YAP and IL‐6. It highlights potential therapeutic strategies targeting these pathways to mitigate vascular remodelling ...
Sheng Ding, Ju Chen, Zhaoyang Li, Yang Yu, Weijie Wang, Yan Liao, Jin Yang, Dianxiang Lu, Yujiang Fan   +8 more
wiley   +1 more source

Colonization and extinction lags drive non‐linear responses to warming in mountain plant communities across the Northern Hemisphere

Ecography, EarlyView.
Global warming is changing plant communities due to the arrival of new species from warmer regions and declining abundance of cold‐adapted species. However, experimentally testing predictions about trajectories and rates of community change is challenging because we normally lack an expectation for future community composition, and most warming ...
Billur Bektaş, Chelsea Chisholm, Dagmar Egelkraut, Joshua Lynn, Sebastián Block, Thomas Deola, Fanny Dommanget, Brian J. Enquist, Deborah E. Goldberg, Sylvia Haider, Aud H. Halbritter, Yongtao He, Renaud Jaunatre, Anke Jentsch, Kari Klanderud, Paul Kardol, Susanne Lachmuth, Gregory Loucougaray, Tamara Münkemüller, Georg Niedrist, Hanna Nomoto, Lorah Seltzer, Joachim Paul Töpper, Lisa J. Rew, Tim Seipel, Manzoor A. Shah, Richard James Telford, Tom W.N. Walker, Shiping Wang, David A. Wardle, Peter Wolff, Yan Yang, Vigdis Vandvik, Jake M. Alexander   +33 more
wiley   +1 more source

Sex‐biased dispersal in the Arabian babbler (Argya squamiceps)

Ibis, EarlyView.
Sex‐biased dispersal plays a central role in shaping social structure and reproductive strategies in many bird species. In the Arabian Babbler Argya squamiceps, a cooperatively breeding species with pronounced male philopatry, dispersal occurs individually or in kin‐based same‐sex coalitions.
Roni Ostreiher, Roger Mundry, Aviad Heifetz   +2 more
wiley   +1 more source