Results 221 to 230 of about 878,658 (384)

Low‐Load Quadriceps Strengthening With Blood Flow Restriction in Adults With Haemophilic Knee Arthropathy: A Randomised Controlled Trial

open access: yesHaemophilia, EarlyView.
Abstract Introduction Haemophilic knee arthropathy leads to a reduction in muscle mass and strength. Blood flow restriction (BFR) involves the application of a compressive cuff that enables strength training with reduced loads. Objective To evaluate safety as the primary outcome and the efficacy (muscle strength and activation, functional capacity and ...
Mar Villalón‐González   +4 more
wiley   +1 more source

Electrophysiological diagnosis using the coefficient of variation of R‐R intervals and a point‐of‐care nerve conduction device is highly correlated to the diagnosis of diabetic polyneuropathy using conventional electromyographs

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Aims/Introduction While treatment for diabetic polyneuropathy (DPN) is still developing, progress has stagnated. The alignment between pathological neurodegeneration in DPN and patients' subjective symptoms is often low, yet these symptoms are frequently used for diagnosis.
Tatsuhito Himeno   +14 more
wiley   +1 more source

Evaluation of the effectiveness and safety of ONO‐2910 for the treatment of diabetic polyneuropathy: An early Phase IIa, multicenter, randomized, placebo‐controlled, double‐blind study in Japanese patients

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Aims/Introduction Diabetic polyneuropathy (DPN) is common in patients with diabetes. Its symptoms include pain, numbness, and impaired neurosensory function. ONO‐2910 promotes Schwann cell differentiation and is being developed for DPN. Materials and Methods This Phase IIa randomized controlled trial evaluated the effectiveness and safety of ...
Yukiko Onishi   +8 more
wiley   +1 more source

Intramuscular tendon length in agonist–antagonist myoneural interface components in transtibial amputation: An anatomic study

open access: yesJournal of Anatomy, EarlyView.
Interestingly, this study shows that tendons spanned over 75% of the distal muscle belly in all muscles, crucial for the innovative tibiotalar agonist–antagonist myoneural interface (AMI) construction. AMI simulates natural muscle–tendon interaction in amputees, improving prosthetic control despite anatomical constraints.
Viktoria Witowski   +13 more
wiley   +1 more source

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