Results 31 to 40 of about 37,146 (263)

Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino, Lavanya Muthukumar, Evan L. Reynolds, Peter Todd, Sinem Ovunc, Sheng Chih Jin, Zitian Tang, Simone Thomas, PNRR Study Group, Ahmet Höke, Brian C. Callaghan, Sarah Berth, Vinay Chaudhry, David Cornblath, Leana Doherty, Lindsey Hayes, Hristelina Ilieva, Thomas Lloyd, Mohammad Khoshnoodi, Brett McCray, Brett Morrison, Bipasha Mukherjee‐Clavin, Lyle Ostrow, Michael Polydefkis, Ricardo Roda, Charlotte Sumner   +25 more
wiley   +1 more source

High resolution ultrasonography of the tibial nerve in diabetic peripheral neuropathy

Journal of Ultrasonography, 2017
Aim of the study: High-resolution ultrasonography of the tibial nerve is a fast and non invasive tool for diagnosis of diabetic peripheral neuropathy. Our study was aimed at finding out the correlation of the cross sectional area and maximum thickness ...
Kunwarpal Singh, Kamlesh Gupta, Sukhdeep Kaur   +2 more
doaj   +1 more source

Is the Outcome of Diagnostic Nerve Block Related to Spastic Muscle Echo Intensity? A Retrospective Observational Study on Patients with Spastic Equinovarus Foot

Journal of Rehabilitation Medicine, 2022
Objective: To investigate the relationship between spastic calf muscles echo intensity and the outcome of tibial nerve motor branches selective block in patients with spastic equinovarus foot. Design: Retrospective observational study.
Mirko Filippetti, Rita Di Censo, Valentina Varalta, Alessio Baricich, Andrea Santamato, Nicola Smania, Alessandro Picelli   +6 more
doaj   +1 more source

Biointegrated Battery‐Based Electroceuticals

Advanced Materials, EarlyView.
Biointegrated batteries go beyond passive power to serve as active therapeutic platforms for delivering programmable electrical cues and bioactive agents. This review examines their mechanisms and applications and provides a framework to guide battery‐based therapeutic design and clinical translation.
Yan Zhou, Zhilian Yue, Zhiqi Chen, Danming Chao, Xiaoteng Jia, Gordon Wallace, Caiyun Wang   +6 more
wiley   +1 more source

Nerve ultrasound in painful diabetic neuropathy: a pilot study of sural and tibial nerves

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery
Background This case–control study investigated the role of nerve ultrasound measurement of the sural and tibial nerve cross-sectional area (CSA) in assessing painful diabetic neuropathy (PDN).
Ahmed Sami Alkotami, Saly Hasan Elkholy, Ahmed Mohamed Elshamy, Wael Ahmed Fadel, Ehab Ahmed Shawky Elseidy, Aya Elsaid Zhran   +5 more
doaj   +1 more source

An unexpected complication of anterior ankle arthroscopy: Section of the posterior tibial neurovascular bundle

Foot & Ankle Surgery: Techniques, Reports & Cases, 2022
Background: This paper reports for the first time in the literature a case of sectioning of the posterior tibial neurovascular pedicle after an anterior ankle arthroscopy.
Matthieu Peras, MD, Jean-Baptiste De Villeneuve Bargemon, MD, Euriell Mingant, MD, Emilie Bougie, MD, Charlotte Jaloux, MD   +4 more
doaj   +1 more source

Amuc_1473 Links Gut Microbes to Skeletal Homeostasis and Counteracts Multifactorial Osteoporosis

Advanced Science, EarlyView.
Amuc_1473, a previously uncharacterized protein enriched in Akkermansia muciniphila‐derived extracellular vesicles, is identified as a gut–bone messenger that promotes osteogenesis and inhibits osteoclastogenesis by engaging transcriptional and translational regulators in bone cells.
Shan‐Shan Rao, Hai‐Jin Zeng, Zun Wang, Chun‐Gu Hong, Yi‐Juan Tan, Yan‐Xin Duan, Jing‐Yao Luo, Ming‐Jie Luo, Yi‐Wei Liu, Xin Wang, Yi Luo, Teng‐Fei Wan, Yong Zhou, Zheng‐Guang Wang, Guo‐Wen Hu, Hao Yin, Xin‐Yue Hu, Zhen‐Xing Wang, Ze‐Hui He, Si‐Yi Cheng, Wei Du, Zhe Guan, Hai‐Li Lang, Hong‐Ji Liu, Jia Cao, Peng Chen, Jiang‐Hua Liu, Hui Xie, Chun‐Yuan Chen   +28 more
wiley   +1 more source

Bioadhesive Hydrogel With Polyphenol‐Armored Nanogene Rejuvenates Chondrocyte Senescence for Aged Osteoarthritis Therapy

Advanced Science, EarlyView.
An adhesive hydrogel depot with polyphenol‐armored nanogenes is developed for treating aged osteoarthritis. This system maintains miR‐140 bioactivity, prolongs its intra‐articular retention, and enhances transfection into chondrocytes, leading to the downregulation of senescence‐associated pathways.
Liwei Yan, Runze Yang, Ting Zhou, Tianhao Xu, Yongqi Li, Yuelin Hu, Minghao Ge, Lei Zhang, Xiong Lu, Chaoming Xie, Weili Fu   +10 more
wiley   +1 more source

Orchestrated Engineered Polyphenol‐Peptide Condensates Coupled With β‐GP Reverses Diabetic Osteoporosis by Remodeling Mitophagy

Advanced Science, EarlyView.
A multifunctional β‐GP@EGCG‐E7 nanoplatform is engineered by polyphenol–peptide condensation and phosphate loading. Bone‐targeted delivery, antioxidant and anti‐inflammatory activity, and mitophagy restoration are integrated in one system, enabling protection of osteoblasts and endothelial cells and promoting bone regeneration under diabetic ...
Xiuyun Xu, Meiqin Zhang, Ting Wu, Erfan Wei, Andrei Y. Hancharou, Zeying Wang, Zijuan Wang, Letian Lv, Likun Wu, Xingtong Pan, Qiyue Zhu, Xinyi Dong, Hao Liu, Yongsheng Zhou   +13 more
wiley   +1 more source

Uncommon complication in traumatic ACL rupture: Tibial neuropathy due to popliteus muscle haemorrhage: A case report

Journal of Orthopaedic Reports
Background: Popliteus muscle haemorrhage is a rare cause of tibial mononeuropathy after severe knee trauma. Case report: 57-year-old patient with left knee trauma presented with knee instability, sensory loss over the sole of the foot and a partial foot ...
Maarten Rombauts, Arne Hautekiet, Koen Matthys, Willem Goethals   +3 more
doaj   +1 more source