Results 61 to 70 of about 1,227,173 (261)

BRCA1 Mutation‐Recognizing Tetrahedral Framework Nucleic Acid Nanoplatform Enables Coordinated PARP/WEE1 Inhibition and STING‐Associated Antitumor Immunity in Ovarian Cancer

Advanced Science, EarlyView.
BRCA1 mutation‐responsive FBOA‐tFNA selectively recognizes mutant transcripts and coordinates reduction‐responsive intracellular delivery of olaparib and adavosertib, amplifying DNA damage and weakening G2/M checkpoint protection. These effects are accompanied by STING‐associated immune activation and stronger antitumor immunity, while sequential anti ...
Chenyi Wang, Mengying Yao, Jinhui Xie, Dingjie Wang, Yashi Shi, Xiaodan Mao, Chunhua Lu, Pengming Sun   +7 more
wiley   +1 more source

Preoperative planning using computed tomography in tibial plateau levelling osteotomy: A comparison with conventional radiography

Veterinary Medicine and Science, 2022
Background Tibial plateau levelling osteotomy (TPLO) is currently one of the most common surgical procedures for the correction of the stifle joint with a ruptured cranial cruciate ligament.
Jayon Kim, Jaeeun Ko, Kidong Eom, Jaehwan Kim   +3 more
doaj   +1 more source

Geometric analysis evaluating the effect of tibial plateau leveling osteotomy position on postoperative tibial plateau slope

, 2004
SummaryThe tibial plateau leveling osteotomy procedure is designed to neutralize cranial tibial thrust by precisely reducing tibial plateau slope. Despite accurate intraoperative measurement and proximal tibial plateau segment rotation, postoperative ...
R. J. McCarthy, M. P. Kowaleski
core   +1 more source

Comparison of Outcomes of Operatively Treated Bicondylar Tibial Plateau Fractures by External Fixation and Internal Fixation [PDF]

, 2012
The outcome of bicondylar tibial plateau fractures treated with either external fixation (35 patients) or internal fixation (24 patients) was reviewed. Outcome measures included the Rasmussen score, clinical complications, development of osteoarthritis ...
J Keating, CC Chan
core   +2 more sources

Preoperative Sagittal Tibial Tubercle‐Trochlear Groove Distance Predicts Postoperative Outcome in Patients Undergoing Combined Trochleoplasty and Medial Patellofemoral Ligament Reconstruction

Arthroscopy, EarlyView.
Purpose To evaluate the association between the preoperative sagittal tibial tubercle‐trochlear groove (sTTTG) distance and postoperative patient‐reported outcomes after combined patellofemoral ligament reconstruction and deepening trochleoplasty in patients with recurrent lateral patellar instability and high‐grade trochlear dysplasia.
Sebastian Schmidt, Luis Navas, Felix Zimmermann, Abd El Nasser Oudeh, Christian Lattermann, Peter Balcarek   +5 more
wiley   +1 more source

The Forgotten Joint Score Shows High Correlation With Established Anterior Cruciate Ligament Reconstruction Patient‐Reported Outcome Measures While Capturing Joint Awareness and Functional Recovery: A Systematic Review

Arthroscopy, EarlyView.
Purpose To systematically review and analyze the existing literature on the use of the Forgotten Joint Score‐12 (FJS‐12) in patients undergoing anterior cruciate ligament reconstruction (ACLR), with the aim of evaluating its effectiveness as a complementary tool to traditional patient‐reported outcome measures (PROMs) in assessing postoperative ...
Helena Son, Vincent Yu, Prushoth Vivekanantha, Marc Daniel Bouchard, Kanto Nagai, Sachin Tapasvi, Darren de SA   +6 more
wiley   +1 more source

Editorial Commentary: Contact Is Not Containment: In High‐Grade Trochlear Dysplasia, the Patellotrochlear Index Quantifies Cartilage Overlap in the Absence of Osseous Constraint

Arthroscopy, EarlyView.
Abstract Patella alta remains among the most critical anatomical risk factors for recurrent patellofemoral instability and failure of patellar stabilization surgery. The Caton‐Deschamps index references the patella to the tibia by measuring the position of the patella relative to the anterosuperior margin of the tibial plateau.
Dustin J. Kress, Toufic R. Jildeh
wiley   +1 more source

Correlation between three column concept classification and internal fixation procedure of tibial plateau patients at dr. soetomo hospital [PDF]

, 2018
Background: Tibial Plateau Fracture is one of the most common case seen in orthopaedics and the most classification system used is Schaetzker Classification.
Dwikora Novembri Utomo, NIDN. 8897700016, Januar Ari Subiantoro   +1 more
core   +1 more source

Geometric modelling of error sources for tibial plateau levelling osteotomy in the dog

, 2022
Tibial plateau levelling osteotomy is widely performed for stabilization of cranial cruciate ligament deficient stifles in dogs. A wide range of postoperative tibial plateau angles around the target angle has been reported. The main aim of this study was
Nielsen, Michelle Brønniche Møller, von Wenck, Asger, Mazdarani, Parisa, Gundersen, Ragnhild Skogstrøm, Miles, James Edward, P. Mazdarani, J.E. Miles, A. von Wenck, M.B.M. Nielsen, R.S. Gundersen   +9 more
core   +1 more source

Hamstring tendons insertion - an anatomical study

Revista Brasileira de Ortopedia, 2013
OBJECTIVE: To study the anatomy of the hamstring tendons insertion and anatomical rela-tionships. METHODS: Ten cadaver knees with medial and anterior intact structures were selected.
Cristiano Antonio Grassi, Vagner Messias Fruheling, Joao Caetano Abdo, Marcio Fernando Aparecido de Moura, Mario Namba, Joao Luiz Vieira da Silva, Luiz Antonio Munhoz da Cunha, Ana Paula Gebert de Oliveira Franco, Isabel Ziesemer Costa, Edmar Stieven Filho   +9 more
doaj   +1 more source