Results 81 to 90 of about 1,757,568 (299)

Takeuchi's Information Criteria as a form of Regularization

open access: yes, 2018
Takeuchi's Information Criteria (TIC) is a linearization of maximum likelihood estimator bias which shrinks the model parameters towards the maximum entropy distribution, even when the model is mis-specified.
Dixon, Matthew, Ward, Tyler
core   +1 more source

Integration of Spatiotemporal Multi‐Omics in Peach Fruit Unravels a Metabolic Niche and the Genetic Basis of Trichome‐Mediated Stress Adaptation

open access: yesAdvanced Science, EarlyView.
This study constructed the first spatiotemporal multi‐omics map of peach fruit and discovered a key candidate gene that synergistically regulates trichome development and drought tolerance through the jasmonic acid signaling pathway, providing insights into the coupling mechanism between development and stress resistance.
Zhixin Liu   +9 more
wiley   +1 more source

Ammonia Detoxification Inhibits Liver Metastasis by Reshaping Hepatic Microenvironment

open access: yesAdvanced Science, EarlyView.
Liver metastasis diverts aspartate into hyperactive pyrimidine synthesis, disrupting urea cycling and causing pathogenic ammonia accumulation. Ammonia dually reprograms the microenvironment by: (1) activating hepatic stellate cells (HSCs) into pro‐fibrotic metastasis‐associated fibroblasts (MAFs), and (2) suppressing anti‐tumor monocytes/macrophages ...
Sumin Sun   +5 more
wiley   +1 more source

A Review on Galling of Aluminum in Cold Forming Processes

open access: yesDüzce Üniversitesi Bilim ve Teknoloji Dergisi
As world’s sustainability become the most influential topic, aluminum and its alloys are becoming the preferred material of the automotive industry because they allow vehicle weight to be reduced without compromising safety.
Hatice Sandallı, Mert Özdoğan
doaj   +1 more source

Multimodal Multiorgan‐on‐a‐Chip Platform for Probing Liver‐Tumor Interactions and Advancing Prodrug Screening

open access: yesAdvanced Science, EarlyView.
This work introduces a multimodal multi‐OoC platform that overcomes current limitations in liver‐tumor interaction studies and prodrug screening. By integrating dynamic microfluidic circuits, electrochemical sensing, and mass analysis, this platform enables non‐invasive, longitudinal monitoring of drug metabolism and hepatotoxicity, offering a ...
Dan Wang   +10 more
wiley   +1 more source

Les TIC. 'Las TIC'

open access: yes, 2006
ESP
Busquets Bruguera, Francesc   +2 more
openaire   +2 more sources

Pilot Open Case Series of Voice over Internet Protocol-Delivered Assessment and Behavior Therapy for Chronic Tic Disorders [PDF]

open access: yes, 2016
Comprehensive Behavioral Intervention for Tics (CBIT) is an efficacious treatment for children with chronic tic disorders (CTDs). Nevertheless, many families of children with CTDs are unable to access CBIT due to a lack of adequately trained treatment ...
Bauer, Christopher C.   +4 more
core   +1 more source

Programmable RNA N6,2´‐O‐Dimethyladenosine Editing

open access: yesAdvanced Science, EarlyView.
ABSTRACT N6,2’‐O‐dimethyladenosine (m6Am) is a prevalent RNA modification located at the first transcribed nucleotide adjacent to the 5′ cap of mRNAs, where it has been implicated in gene regulation. However, the lack of methods for precise, transcript‐specific manipulation of m6Am has limited its functional dissection.
Yang Li   +9 more
wiley   +1 more source

Enzymatic Basis for the Oxidative Branch of Aromatic Amino Acid Fermentation Leading to p‐cresol Formation

open access: yesAdvanced Science, EarlyView.
In anaerobic bacteria, tyrosine serves as an electron donor in the oxidative Stickland fermentation branch, generating p‐hydroxyphenylacetate, ATP and reduced ferredoxin for decarboxylation into p‐cresol. ABSTRACT The phenolic metabolite p‐cresol is a byproduct of tyrosine fermentation by certain strictly anaerobic bacteria, including the human gut ...
Li Jiang   +15 more
wiley   +1 more source

TICs

open access: yesRevista Iberoamericana de Tecnología en Educación y Educación en Tecnología, 2009
Vivimos en la era de la información y la comunicación. Admiramos y usamos cotidianamente las maravillas que la tecnología actual pone en nuestras manos: INTERNET, cámaras digitales, teléfonos celulares (muchas veces con cámaras digitales incorporadas), bibliotecas digitales, CD, DVD, MP3, MP4, iPod, etc.
Gaitán, María Mercedes   +2 more
  +6 more sources

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