Results 301 to 310 of about 3,153,065 (363)

Long‐Term Stability of Spatial Distribution and Peak Dynamics of Subthalamic Beta Power in Parkinson's Disease Patients

open access: yesMovement Disorders, Volume 40, Issue 6, Page 1070-1084, June 2025.
Abstract Background Subthalamic beta oscillations are a biomarker for bradykinesia and rigidity in Parkinson's disease (PD), incorporated as a feedback signal in adaptive deep brain stimulation with potential for guiding electrode contact selection.
Jennifer K. Behnke   +13 more
wiley   +1 more source

Treatment Efficacy of Theophylline in ADCY5‐Related Dyskinesia: A Retrospective Case Series Study

open access: yesMovement Disorders, Volume 40, Issue 6, Page 1143-1147, June 2025.
Abstract Background ADCY5‐related dyskinesia is a rare disorder caused by mutations in the ADCY5 gene resulting in abnormal involuntary movements. Currently, there are no standardized guidelines to treat this condition. Objective The aim of this study was to evaluate the efficacy of theophylline administration in improving symptoms and quality of life ...
Dirk Taenzler   +3 more
wiley   +1 more source

NLX‐112 Randomized Phase 2A Trial: Safety, Tolerability, Anti‐Dyskinetic, and Anti‐Parkinsonian Efficacy

open access: yesMovement Disorders, Volume 40, Issue 6, Page 1134-1142, June 2025.
Abstract Background Levodopa‐induced dyskinesia (LID) in Parkinson's disease (PD) is associated with ‘false neurotransmitter’ release of dopamine from serotonin (5‐HT) neurons. NLX‐112 is a first‐in‐class, highly selective 5‐HT1A receptor agonist which counteracts LIDs in experimental PD models.
Per Svenningsson   +13 more
wiley   +1 more source

Novel In‐Frame FGF14 Deletion Causes Spinocerebellar Ataxia Type 27A: Clinical Response to Deep Brain Stimulation and 4‐Aminopyridine

open access: yesMovement Disorders, Volume 40, Issue 6, Page 1182-1188, June 2025.
Abstract Background Spinocerebellar ataxia 27A (SCA27A) is a rare neurodegenerative disorder characterized by childhood‐onset tremor and progressive cerebellar dysfunction. SCA27A is usually caused by loss‐of‐function FGF14 variants. Objectives We report the identification of a novel FGF14 variant in a five‐generation family with autosomal dominant ...
Ignacio J. Keller Sarmiento   +6 more
wiley   +1 more source

Antero‐Lateral Subthalamic Nucleus Theta Stimulation Improves Verbal Fluency in Parkinson's Disease

open access: yesMovement Disorders, Volume 40, Issue 6, Page 1195-1199, June 2025.
Abstract Objective Low‐frequency deep brain stimulation (DBS) of the subthalamic nucleus (STN) has been associated with positive effects on verbal fluency (VF) in patients with Parkinson's disease. This prospective study investigates stimulation direction‐dependent and site‐specific effects of theta frequency DBS on VF. Methods In a double‐blind, cross‐
Hannah Schoenwald   +12 more
wiley   +1 more source

Efficacy and Safety of Magnetic Resonance‐Guided Focused Ultrasound Thalamotomy in Essential Tremor: A Systematic Review and Metanalysis

open access: yesMovement Disorders, Volume 40, Issue 6, Page 1020-1033, June 2025.
Abstract Background Magnetic resonance‐guided focused ultrasound (MRgFUS) is an established surgical treatment for essential tremor, providing tremor relief without the need for an incision or general anesthesia. Meta‐analyses have been limited in their exploration of the durability of the treatment effect.
Alyssa Shiramba   +8 more
wiley   +1 more source

Tourette Syndrome Research Highlights from 2018 [version 1; peer review: 2 approved] [PDF]

open access: yes, 2019
Black, Kevin J   +4 more
core   +1 more source

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