Results 161 to 170 of about 1,474,594 (273)

Neurodevelopmental disorders and the gut microbiome: insights into ADHD and tic disorders. [PDF]

Front Microbiol
Li J, Qiu X.
europepmc   +1 more source

Genetic testing in paediatric neurological disorders

Developmental Medicine &Child Neurology, EarlyView.
In this study 390 paediatric patients with neurological disorders underwent genetic testing via exome sequencing, commercial panel, in‐house epilepsy, and movement disorder gene panels. Exome sequencing provides the highest diagnostic yield, and severe developmental delay and hypotonia predicted pathogenic variants in the exome sequencing cohort ...
Wafa Bani Uraba, Byoung Chan Lee, Shekeeb S. Mohammad, Katrina Fisk, Michael Buckley, Russell C. Dale, Tony Roscioli, Paediatric Neurogenomic Working Group, Manoj P. Menezes, Sachin Gupta, Christopher Troedson, Esther Tantsis, Richard Webster, Bruce Bennetts, Deepak Gill, Kavitha Kothur   +15 more
wiley   +1 more source

Nationwide survey of psychopathology and bullying in tic disorders with and without ADHD. [PDF]

Child Adolesc Psychiatry Ment Health
Lin YJ, Tsai FJ, Gau SS.
europepmc   +1 more source

The Rhythmic and the Metronomic: On Charlie Chaplin's Gait

Critical Quarterly, EarlyView.
Matthew Beaumont
wiley   +1 more source

Spatially resolved mapping of histones reveals selective neuronal response in Rett syndrome

The FEBS Journal, EarlyView.
Loss of Mecp2 function is associated with Rett syndrome (RTT). MeCP2 regulates chromatin, yet its influence on histone composition and dynamics is unclear. Combining MALDI‐MSI with LCM–LC–MS/MS, we mapped histone proteoforms across the dentate gyrus, cornu ammonis, and cerebellum in two mouse models of RTT.
Frederike Schäfer, Giuseppina De Rocco, Moritz Völker‐Albert, Ignasi Forne, Nicoletta Landsberger, Axel Imhof, Shibojyoti Lahiri   +6 more
wiley   +1 more source

Periodontitis and Chronic Conditions in Older Adults: A Scoping Review and Evidence Map of Systematic Reviews

Gerodontology, EarlyView.
ABSTRACT Background Periodontitis is a prevalent chronic inflammatory condition that frequently co‐occurs with systemic chronic diseases. Although older adults experience a high burden of both periodontitis and chronic conditions, the extent to which age‐specific evidence has been synthesised remains unclear.
Manisha Tamrakar, Najith Amarasena, Kym Michelle McCormick, Liana Luzzi, Gloria Mejia   +4 more
wiley   +1 more source

Metabolic Profiling of Circulating and Tumour‐Infiltrating T Cells Uncovers Bioenergetic Checkpoints Linked With Immune and Clinical Skewing in Melanoma Patients

Immunology, EarlyView.
In this study, we revealed the disturbed metabolic status of circulating and tumour‐infiltrating CD4+ and CD8+ T cells in melanoma patients through targeted metabolomic and lipidomic (on sorted subsets) and at single cell level using the SCENITH method.
Hugo Brouque, Kareem Mahdy, Stephane Mouret, Sylvain Henry, Camille Niveau, Mélanie Cettour‐Cave, Martin Pelosse, Florence de Fraipont, Julie Charles, Andrei Turtoi, Philippe Saas, Caroline Aspord   +11 more
wiley   +1 more source

Clinical significance of serum brain-derived neurotrophic factor and serotonin levels in children with tic disorders. [PDF]

Front Pediatr
Zhang X, Chen N, Zhu X, Wang C.
europepmc   +1 more source

Neurocognitive profiles in early childhood in relation to clinical and functional outcomes in middle childhood in offspring at familial high‐risk of schizophrenia or bipolar disorder: The Danish High‐Risk and Resilience Study

Journal of Child Psychology and Psychiatry, EarlyView.
Background Widespread neurocognitive impairments exist in children at familial high‐risk of schizophrenia (FHR‐SZ), whereas evidence is mixed in children at FHR of bipolar disorder (FHR‐BP). Neurocognitive heterogeneity is well‐established, but associations with longitudinal clinical and functional outcomes remain unexplored.
Nicoline Hemager, Jens Richardt Møllegaard Jepsen, Aja Neergaard Greve, Lotte Veddum, Anne Søndergaard, Mette Falkenberg Krantz, Ole Mors, Anne Amalie Elgaard Thorup, Merete Nordentoft, Maja Gregersen   +9 more
wiley   +1 more source

Immune dysregulation in pediatric tic disorders: mechanisms, biomarkers, and therapeutic frontiers. [PDF]

Front Immunol
Sun X, Bai X.
europepmc   +1 more source