ERNEST COST action overview on the (patho)physiology of GPCRs and orphan GPCRs in the nervous system
British Journal of Pharmacology, Volume 182, Issue 14, Page 3178-3210, July 2025.G protein‐coupled receptors (GPCRs) are a large family of cell surface receptors that play a critical role in nervous system function by transmitting signals between cells and their environment. They are involved in many, if not all, nervous system processes, and their dysfunction has been linked to various neurological disorders representing important
Necla Birgül Iyison +15 more
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Therapeutic Approach to Primary Tic Disorders and Associated Psychiatric Comorbidities. [PDF]
Brain SciBerzosa-Gonzalez I +4 more
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Clinical characteristics of comorbid tic disorders in autism spectrum disorder: exploratory analysis. [PDF]
Child Adolesc Psychiatry Ment Health, 2023 Kim YR +5 more
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Progress on the development of Class A GPCR‐biased ligands
British Journal of Pharmacology, Volume 182, Issue 14, Page 3249-3300, July 2025.Class A G protein‐coupled receptors (GPCRs) continue to garner interest for their essential roles in cell signalling and their importance as drug targets. Although numerous drugs in the clinic target these receptors, over 60% GPCRs remain unexploited. Moreover, the adverse effects triggered by the available unbiased GPCR modulators, limit their use and
Paula Morales +20 more
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A systematic review exploring perceptions of Tourette syndrome and tic disorders using the common-sense model of illness representations. [PDF]
Psychol HealthPetter C, Khan K, Babbage C, Davies EB.
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Management of allergic rhinitis improves clinical outcomes of difficult-to-treat tic disorders or attention-deficit/hyperactivity disorders. [PDF]
Allergol Select, 2023 Yu RL +4 more
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Adaptive functioning in children and young adults with monogenic neurodevelopmental disorders
Developmental Medicine &Child Neurology, Volume 67, Issue 7, Page 953-962, July 2025.Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16264 Abstract Aim To examine the adaptive behaviour profiles of children with monogenic neurodevelopmental disorders (NDDs) to determine whether syndrome‐specific or transdiagnostic approaches provide a better understanding of the adaptive behavioural phenotypes of these NDDs ...
Emma K. Baker +8 more
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Sex Differences in Natural History and Health Outcomes Among Individuals With Tic Disorders. [PDF]
NeurologyDy-Hollins ME +14 more
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Tic Disorders, Anti-Tic Medications, and Risk of Atopy. [PDF]
Mov Disord Clin Pract, 2022 Hakimi M, Skinner S, Maurer CW.
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