Results 271 to 280 of about 223,828 (347)

Treatment Efficacy of Theophylline in ADCY5‐Related Dyskinesia: A Retrospective Case Series Study

Movement Disorders, Volume 40, Issue 6, Page 1143-1147, June 2025.
Abstract Background ADCY5‐related dyskinesia is a rare disorder caused by mutations in the ADCY5 gene resulting in abnormal involuntary movements. Currently, there are no standardized guidelines to treat this condition. Objective The aim of this study was to evaluate the efficacy of theophylline administration in improving symptoms and quality of life ...
Dirk Taenzler, Frank Hause, Andreas Merkenschlager, Andrea Sinz   +3 more
wiley   +1 more source

Improving Identification of Tic Disorders in Children. [PDF]

Evid Based Pract Child Adolesc Ment Health
Wardrop RC, Lewin AB, Adams HR, Vermilion JA, Cuffe SP, Danielson ML, Bitsko RH, Cai B, Hardin JW.   +8 more
europepmc   +1 more source

NLX‐112 Randomized Phase 2A Trial: Safety, Tolerability, Anti‐Dyskinetic, and Anti‐Parkinsonian Efficacy

Movement Disorders, Volume 40, Issue 6, Page 1134-1142, June 2025.
Abstract Background Levodopa‐induced dyskinesia (LID) in Parkinson's disease (PD) is associated with ‘false neurotransmitter’ release of dopamine from serotonin (5‐HT) neurons. NLX‐112 is a first‐in‐class, highly selective 5‐HT1A receptor agonist which counteracts LIDs in experimental PD models.
Per Svenningsson, Per Odin, Filip Bergquist, Karin Wirdefeldt, Dag Nyholm, Mattias Andréasson, Ioanna Markaki, Anders C. Johansson, Måns Jergil, Christopher Jankosky, Mark A. Varney, Fabienne Herbrecht, Steven A. Johnson, Adrian Newman‐Tancredi   +13 more
wiley   +1 more source

Novel In‐Frame FGF14 Deletion Causes Spinocerebellar Ataxia Type 27A: Clinical Response to Deep Brain Stimulation and 4‐Aminopyridine

Movement Disorders, Volume 40, Issue 6, Page 1182-1188, June 2025.
Abstract Background Spinocerebellar ataxia 27A (SCA27A) is a rare neurodegenerative disorder characterized by childhood‐onset tremor and progressive cerebellar dysfunction. SCA27A is usually caused by loss‐of‐function FGF14 variants. Objectives We report the identification of a novel FGF14 variant in a five‐generation family with autosomal dominant ...
Ignacio J. Keller Sarmiento, Roberta Bovenzi, Morgan Kinsinger, Lisa Kinsley, Bernabe I. Bustos, Dimitri Krainc, Niccolò E. Mencacci   +6 more
wiley   +1 more source

Antero‐Lateral Subthalamic Nucleus Theta Stimulation Improves Verbal Fluency in Parkinson's Disease

Movement Disorders, Volume 40, Issue 6, Page 1195-1199, June 2025.
Abstract Objective Low‐frequency deep brain stimulation (DBS) of the subthalamic nucleus (STN) has been associated with positive effects on verbal fluency (VF) in patients with Parkinson's disease. This prospective study investigates stimulation direction‐dependent and site‐specific effects of theta frequency DBS on VF. Methods In a double‐blind, cross‐
Hannah Schoenwald, Bahne H. Bahners, Silja Kannenberg, Till A. Dembek, Michael T. Barbe, Dafina Sylaj, Anja Spiewok, Saskia Elben, Tomke Muettel, Jan Vesper, Philipp Slotty, Alfons Schnitzler, Stefan J. Groiss   +12 more
wiley   +1 more source

Efficacy and Safety of Magnetic Resonance‐Guided Focused Ultrasound Thalamotomy in Essential Tremor: A Systematic Review and Metanalysis

Movement Disorders, Volume 40, Issue 6, Page 1020-1033, June 2025.
Abstract Background Magnetic resonance‐guided focused ultrasound (MRgFUS) is an established surgical treatment for essential tremor, providing tremor relief without the need for an incision or general anesthesia. Meta‐analyses have been limited in their exploration of the durability of the treatment effect.
Alyssa Shiramba, Steven Lane, Nicola Ray, Tom Gilbertson, Rajesha Srinivasaiah, Jay Panicker, Mark Radon, Jibril Osman‐Farah, Antonella Macerollo   +8 more
wiley   +1 more source

Clinical Study of Limosilactobacillus reuteri for the Treatment of Children with Chronic Tic Disorders/Tourette Syndrome: A Mid-Term Efficacy Evaluation. [PDF]

Neurol Ther
Liang Y, Wan L, Wang G, Yan H, Zhang J, Liu X, Zhang Z, Zhu G, Yang G.   +8 more
europepmc   +1 more source

Validation and assessment of the self-injurious behavior scale for tic disorders (SIBS-T). [PDF]

Sci Rep
Szejko N, Schlarmann HG, Pisarenko A, Haas M, Brandt V, Jakubovski E, Müller-Vahl KR.   +6 more
europepmc   +1 more source

Theta‐Gamma Subthalamic Stimulation for Verbal Fluency in Parkinson's Disease: A Randomized, Crossover Trial

Movement Disorders, Volume 40, Issue 6, Page 1189-1194, June 2025.
Abstract Background High‐frequency deep brain stimulation (DBS) of the subthalamic nucleus (STN) improves Parkinson's disease (PD) motor symptoms but may deteriorate verbal fluency (VF). Theta stimulation showed potential cognitive benefits associated with motor worsening. Objectives This randomized, double‐blind, crossover study evaluated the efficacy
Gabriele Imbalzano, Elisa Montanaro, Claudia Ledda, Francesca Donetto, Francesco D'Angelo, Corrado Campisi, Carlo Alberto Artusi, Alberto Romagnolo, Mario Giorgio Rizzone, Marco Bozzali, Leonardo Lopiano, Maurizio Zibetti   +11 more
wiley   +1 more source

Evaluating Problematic Smartphone Use Among Chinese Primary School Students Using SABAS: An IRT and Network Analysis

International Journal of Methods in Psychiatric Research, Volume 34, Issue 2, June 2025.
ABSTRACT Objectives This study assessed the psychometric properties of the Smartphone Application‐Based Addiction Scale (SABAS) among Chinese primary school students, focusing on validity, reliability, and factor structure using Item Response Theory (IRT) and Network Analysis (NA). Methods Data were collected from 1108 primary school students in China (
Siyang Liu, Qian Chen, Jiayang Li, Yimeng Zhu, Xiaorong Guo, Xin Zhao   +5 more
wiley   +1 more source