Results 131 to 140 of about 2,440,906 (285)

Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment

Med Research, EarlyView.
An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu, Weiquan Liao, Ziqi Lian, Mengdan Zhang, Chenxing Wang, Xingjia Zhu, Lin Zhang, Jian Chen, Zhichao Lu, Peipei Gong   +9 more
wiley   +1 more source

Recent Advances in Cryogel Applications for Musculoskeletal Regeneration

Medicinal Research Reviews, EarlyView.
ABSTRACT Hydrogels have been widely used in tissue engineering due to their high‐water content and biocompatibility, yet their densely cross‐linked microstructure inherently limits cell infiltration, mass transport, and mechanical support. Cryogels, formed through partial freezing and crosslinking under subzero conditions, provide unique 3D macroporous
Dohee Kim, Shinwon Kang, Hyejin Jo, Inseon Kim, Seunghun S. Lee   +4 more
wiley   +1 more source

Boronic Acid Inhibitors of β‐Lactamases: A Promising Strategy Against Antimicrobial Resistance

Medicinal Research Reviews, EarlyView.
ABSTRACT The rise of antimicrobial resistance (AMR) poses a critical threat to global health, mostly due to the proliferation of β‐lactamases, a class of enzymes responsible for the inactivation of β‐lactam antibiotics. Among the most promising strategies to restore β‐lactam efficacy is the use of β‐lactamase inhibitors (BLIs), with boronic acid ...
Nicolò Santi, Federico Corsini, Robert A. Bonomo, Emilia Caselli, Fabio Prati   +4 more
wiley   +1 more source

Aptamer–Based Targeted Protein Degradation: Mechanistic Principles, Delivery Strategies, and Translational Opportunities

Medicinal Research Reviews, EarlyView.
ABSTRACT Targeted elimination of pathogenic proteins remains a fundamental challenge in therapeutic intervention, particularly for proteins considered “undruggable” by conventional inhibition‐based approaches. Aptamer–based targeted protein degradation (TPD) has emerged as a versatile strategy that leverages the high specificity, structural ...
Ambrin Malik, Suyeon Son, Jaesung Lee, Ki Soo Park   +3 more
wiley   +1 more source

Tick–borne diseases in Europe

, 2011
Tick borne diseases are emerging in several european countries. Those transmitted by the tick Ixodes ricinus and Hyalomma spp are the most worrying. In this presentation an overview of the most frequently transmitted pathogens in Europe and the priority ...
Pfister, K., Rizzoli, Annapaola, Groshup, M.   +2 more
core   +1 more source

[Tick-borne diseases].

Pediatria polska, 1996
In Poland since 1992 there is a rapid increase in the incidence of Lyme borreliosis and arboviral encephalitis. The role of ticks in spread of this diseases is discussed. The clinical picture, diagnosis and treatment of the Lyme disease, tick encephalitis tularemia and babesiosis are discussed.
openaire   +1 more source

Attitudes Toward Prenatal Interventions in the Fanconi Anemia Community

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective In‐utero cell and gene therapies may offer prenatal treatment options for inherited diseases. Preclinical data suggests in‐utero (IU) hematopoietic stem cell transplantation (HSCT) could prevent Fanconi anemia (FA) related bone marrow failure without genotoxic conditioning or immune suppression.
Tony Lum, Catherine Lee, Tippi MacKenzie, Billie Lianoglou, Agnieszka Czechowicz   +4 more
wiley   +1 more source

Assessment of insecticide use practices in licensed pest control operators in North Carolina

Pest Management Science, EarlyView.
A statewide survey of 105 licensed North Carolina pesticide operators found ants, mosquitoes, and aphids as top target pests, pyrethroids as the dominant insecticide class (68%), and limited resistance monitoring, establishing a baseline for future insecticide resistance management and outreach.
Kaylin Russell, Stephanie Richards, Sinan Sousan, Jo Anne Balanay   +3 more
wiley   +1 more source

Camels as a Climate‐Resilient Linchpin for Sustainable Development in Global Drylands

Sustainable Development, EarlyView.
ABSTRACT Camels represent a significant, yet underutilized, asset for advancing integrated sustainable development in the world's expanding drylands. Previous reviews have examined camels' physiology, milk composition, or pastoral systems in isolation; this review examines their potential as a climate‐resilient linchpin for food systems by synthesizing
Ayana Angassa, Minyahel Tilahun, Solomon G. Tesfamichael   +2 more
wiley   +1 more source

Evaluation of Nanonanoliposomal Curcumin on Cutaneous Leishmaniasis Skin Lesions Caused by Leishmania major in BALB/c Mice

Iranian Journal of Parasitology
Background: Curcumin is an extract of rhizome turmeric (diferuloylmethane), with antioxidant, anti-inflammatory, antimicrobial, and anti-parasitic properties, which making it a potential candidate for the treatment of leishmaniasis.
Sedigheh Shirmohammad, Mahdi Mohebali, Fateme Arabkhazaeli, Jalal Hassan, David Shayan, Narges Amininia, Parviz Shayan   +6 more
doaj