Results 51 to 60 of about 76,785 (327)

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Novel Functional Materials via 3D Printing by Vat Photopolymerization

Advanced Functional Materials, EarlyView.
This Perspective systematically analyzes strategies for incorporating functionalities into 3D‐printed materials via Vat Photopolymerization (VP). It explores the spectrum of achievable functionalities in recently reported novel materials—such as conductive, energy‐storing, biodegradable, stimuli‐responsive, self‐healing, shape‐memory, biomaterials, and
Sergey S. Nechausov, Patrick Fesser, Boris A. Bulgakov, Ulrich S. Schubert   +3 more
wiley   +1 more source

Factors influencing the prevalence and distribution of ticks and tick- borne pathogens among domestic animals in Malaysia [PDF]

, 2016
Changes in tick-vector densities and a resultant incidence of tick-borne diseases are caused mainly by human activities affecting the environmental ecosystem, especially in tropical countries.
Lau, Seng Fong, Megat Abd Rani, Puteri Azaziah, Mohammed, Konto, Shettima, Yasheruram M., Tukur, Salamatu Mohammed, Watanabe, Mahira, Watanabe, Malaika   +6 more
core  

Co-infection of tick-borne bacterial pathogens in ticks in Inner Mongolia, China.

PLoS Neglected Tropical Diseases, 2023
Tick-borne infectious diseases pose a serious health threat in certain regions of the world. Emerging infectious diseases caused by novel tick-borne pathogens have been reported that are causing particular concern.
Dan Liu, Wulantuya, Hongxia Fan, Xiaona Li, Fangchao Li, Ting Gao, Xuhong Yin, Zitong Zhang, Minzhi Cao, Hiroki Kawabata, Kozue Sato, Norio Ohashi, Shuji Ando, Gaowa   +13 more
doaj   +1 more source

Bioprinting Organs—Science or Fiction?—A Review From Students to Students

Advanced Healthcare Materials, EarlyView.
Bioprinting artificial organs has the potential to revolutionize the medical field. This is a comprehensive review of the bioprinting workflow delving into the latest advancements in bioinks, materials and bioprinting techniques, exploring the critical stages of tissue maturation and functionality.
Nicoletta Murenu, Camilla Mussoni, Mateo S. Andrade Mier, Paula Buettner, Nathaly Chicaiza‐Cabezas, Yi‐Yu Robin Dai, Jessica Faber, Maren Fiedler, Zan Lamberger, Xuen Jen Ng, Vanessa Moessler, Anna Rederer, Jonas Roeder, Sabrina Stecher, Katinka Theis, Jeanette Weigelt, Silvia Budday, Gregor Lang, Natascha Schaefer   +18 more
wiley   +1 more source

Increased Anti‐Psoriatic Effect of Anti‐Inflammatory Dendrimers Using Fluid Catanionic Vesicle‐Based Topical Formulations

Advanced Healthcare Materials, EarlyView.
Next‐Generation Psoriasis Therapy – With advanced dendrimer‐based formulations, this study paves the way for highly effective, skin‐permeable treatments. Encapsulated in fluid catanionic vesicles, IMD‐006 and its analogues show promising anti‐psoriatic effects offering a targeted, non‐invasive approach to managing chronic skin inflammation.
Ranime Jebbawi, Abdelouahd Oukhrib, Emily Clement, Hélène Labie, Stéphanie Cassel, Séverine Fruchon, Anne‐Marie Caminade, Michel Simon, Rémy Poupot, Cédric‐Olivier Turrin, Muriel Blanzat   +10 more
wiley   +1 more source

Molecular detection of tick-borne pathogen diversities in ticks from livestock and reptiles along the shores and adjacent islands of lake Victoria and lake Baringo, Kenya [PDF]

, 2017
Tick-borne pathogens (TBPs) are responsible for some of the most serious emerging infectious diseases facing sub-Saharan Africa (SSA) and the rest of the world today (1, 2).
Ajamma, Allsopp, Altschul, Andoh, Bengis, Burgdorfer, Burridge, Collins, Cook, Crowder, Crump, Dantas-Torres, Daszak, de la Fuente, De Sousa, Drummond, Dunster, Fyumagwa, Ghai, Gortazar, Gubbels, Guindon, Hess, Homewood, Horak, Hornok, Kamani, Kariuki, Katoh, Kearse, Kelly, Kiara, Kipkorir, Kock, Kumsa, Latif, Latif, Lwande, Machado-Ferreira, Maina, Maina, Mati, Matsumoto, Maxwell, Mediannikov, Miller, Minakawa, Mokrani, Morzaria, Moumouni, Mukhebi, Mwamuye, Ngumi, Njiiri, Norval, Nowak, Olwoch, Omondi, Onchuru, Oura, Parola, Parola, Punyua, Rosenstein, Rubaire-Akiiki, Saitou, Sang, Sang, Thumbi, Tigoi, Tijsse-Klassen, Tokarz, Trout Fryxell, Uilenberg, Walker, Walker, Walker, Walker, Wanzala, Wanzala, Wen, Wesonga, Wesonga, Whiley, Wiethoelter, Zhu   +85 more
core   +2 more sources

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

Ticks and tick-borne diseases [PDF]

Médecine et Maladies Infectieuses, 2019
Ticks are a major group of arthropod vectors, characterized by the diversity of pathogens they transmit, by their impact on human and animal health, and by their socioeconomic implication especially in countries of the Southern Hemisphere. In Europe, Ixodes is the most important tick due to its wide distribution in the ecosystems and the variety of ...
N, Boulanger, P, Boyer, E, Talagrand-Reboul, Y, Hansmann   +3 more
openaire   +2 more sources

Delivery of Multifunctional Microspheres via Intravesical Instillation for Bladder Carcinoma: Therapeutic Potential and Mechanistic Insights

Advanced Healthcare Materials, EarlyView.
PCTM microspheres were successfully synthesized using microfluidic and click chemistry techniques.In Vivo and in vitro experiments have shown that PCTM microspheres have obvious targeting, adhesion, membrane penetration and anti‐tumor properties for bladder tumors.The antitumor mechanism of PCTM microspheres is to indirectly induce S‐stage blockage of ...
Zhaoxiang Lu, Wentie Yang, Youzhi Hong, Yusen Qiao, Chaozhao Liang   +4 more
wiley   +1 more source