Results 31 to 40 of about 282,764 (203)

From Oncolysis to Adaptive Immunity: Yellow Fever Virus 17D and Ruxolitinib Activate Antitumor Immune Responses in Pancreatic Cancer Models

Biomedicines
Background: Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal cancers, with a five-year survival rate of less than 12%. Oncolytic viruses are considered a promising immunotherapeutic approach, but their effectiveness is often limited
Kirill N. Trachuk, Yulia K. Biryukova, Vitalii A. Kapranov, Alina S. Nazarenko, Ekaterina A. Orlova, Grigory L. Kozhemyakin, Grigory A. Demyashkin, Ilya V. Gordeychuk, Aydar A. Ishmukhametov, Nadezhda M. Kolyasnikova   +9 more
doaj   +1 more source

Tick-borne encephalitis (TBE) [PDF]

Tick-borne encephalitis, or TBE, is a human viral infectious disease involving the central nervous system. TBE is caused by the tick- borne encephalitis virus (TBEV), a member of the family Flaviviridae, and was initially isolated in 1937.
Överby, Anna K.,, Gredmark-Russ, Sara,
core   +2 more sources

Immunotherapeutic Potential of the Yellow Fever Virus Vaccine Strain 17D for Intratumoral Therapy in a Murine Model of Pancreatic Cancer

Vaccines
Objective: We evaluate the immunotherapeutic potential of the yellow fever virus vaccine strain 17D (YFV 17D) for intratumoral therapy of pancreatic cancer in mice.
Alina S. Nazarenko, Yulia K. Biryukova, Kirill N. Trachuk, Ekaterina A. Orlova, Mikhail F. Vorovitch, Nikolay B. Pestov, Nick A. Barlev, Anna I. Levaniuk, Ilya V. Gordeychuk, Alexander S. Lunin, Grigory A. Demyashkin, Petr V. Shegai, Andrei D. Kaprin, Aydar A. Ishmukhametov, Nadezhda M. Kolyasnikova   +14 more
doaj   +1 more source

Chronic tick-borne encephalitis

, 2021
The article is devoted to Kozhevnikov's epilepsy, one of the most common and, in fact, pathognomonic manifestations of the chronic course of tick-borne encephalitis.
L. S. Levina, M. S. Szherbinina, E. I. Naumov, N. G. Bochkova, V. V. Pogodina, E. G. Demianovskaia, A. S. Vasiliev, T. A. Snitur   +7 more
core   +1 more source

Tick-Borne Infections Incidence among the Population of Siberian and Far East Federal Districts in 2009 and 2010 and Prognosis for 2011

Проблемы особо опасных инфекций, 2011
Presented are the data on tick-borne infections (tick-borne encephalitis, tick-borne borrelioses and rickettsioses) incidence among the population of the constituent entities of Siberian and Far East Federal Districts in 2009 and 2010.
A. Ya. Nikitin, E. A. Sidorova, E. I. Andaev, M. V. Chesnokova   +3 more
doaj   +1 more source

Clinical and epidemiological features of tick-borne encephalitis in adults in Novosibirsk in 2014-2023

Лечащий Врач
Background. Fundamental differences in the scale, overall picture of tick-borne encephalitis, the structure and quality of its clinical variants determine the need for regular analytical work and competent dynamic accounting of clinical, epidemiological ...
Yu. V. Kazakova, Ya. S. Ulyanova, E. I. Krasnova, T. G. Burmistrova, V. G. Kuznetsova, E. N. Usolkina, V. V. Provorova, P. N. Verchenko, P. D. Urusova   +8 more
doaj   +1 more source

Impact of climate on Australian, non‐Vector‐borne infectious animal diseases: A scoping review

Australian Veterinary Journal, EarlyView.
Changes to Australia's climate continue to be increasingly relevant for human, animal and planetary health, and have far‐reaching impacts on disease emergence and food security. There is a deficit of knowledge in Australia around how climatic conditions are affecting infectious animal diseases, beyond the more obvious spatial distribution changes of ...
G Terry, MP Ward
wiley   +1 more source

Tick-borne Encephalitis Vaccines

Journal of Bioterrorism & Biodefense, 2011
Tick-borne encephalitis (TBE) is a disease that is found from western Europe across Asia and into Japan. In recent years the incidence rate has been increasing as has the endemic range of the virus. Tick-borne encephalitis is caused by three genetically distinct sutypes of viruses within a single TBE virus (TBEV) serocomplex.
Axel T, Lehrer, Michael R, Holbrook
openaire   +2 more sources

Clinical and laboratory parameters when using combined therapy (immunoglobulin and interferon α2v) in patients with meningeal form of tick-borne encephalitis

Бюллетень сибирской медицины, 2012
Presents the results of a comparative study of combined therapy (immunoglobulin against tick-borne encephalitis in conjunction with reaferon-ES-lipint) and base treatments (immunoglobulin against tick-borne encephalitis), meningeal form of tick-borne ...
N. Sh. Salabai, K. I. Chuikova
doaj   +1 more source

Clinical and genetic characterization of intellectual disability

Developmental Medicine &Child Neurology, EarlyView.
This study examines the etiological factors and comorbidities in a large cohort of Finnish patients with intellectual disability. Genetic causes—including chromosomal abnormalities and pathogenic gene variants—were more frequently identified in individuals with moderate to profound intellectual disability.
Aarni Venetvaara, Minna Kraatari‐Tiri, Jussi‐Pekka Tolonen, Marko Merikukka, IDGEN Study Group, Hannaleena Kokkonen, Teija Paakkola, Susanna Varis, Antti Dahl, Jarmo Körkkö, Jonna Komulainen‐Ebrahim, Jukka Moilanen, Johanna Uusimaa, Outi Kuismin, Elisa Rahikkala   +14 more
wiley   +1 more source