Results 191 to 200 of about 51,206 (279)

Predictive Modelling of Tick Distribution: A Machine Learning Approach to Ixodes ricinus Abundance

open access: yesConcurrency and Computation: Practice and Experience, Volume 38, Issue 1, January 2026.
ABSTRACT The resurgence of tick‐borne diseases necessitates predictive frameworks that integrate both high accuracy and ecological relevance. This study develops a comprehensive machine learning pipeline to forecast the occurrence of Ixodes ricinus, a principal tick vector in Europe, leveraging high‐dimensional climatic, environmental, and land‐use ...
Kruttika Jamalpuram   +6 more
wiley   +1 more source

Multi‐omics analysis identifies PUS7 as an immune modulator driving NETs‐mediated macrophage polarization in pancreatic cancer

open access: yesClinical and Translational Medicine, Volume 16, Issue 1, January 2026.
PUS7 reshapes the PDAC immune landscape primarily by inducing NETs, which drive macrophage polarization from M1 to M2, fostering immune suppression and tumour progression. The inhibitory effects of S428‐1145 and DNase I on pancreatic cancer are mediated through blocking the PUS7/NETs/M2 macrophage pathway.
Jike Fang   +8 more
wiley   +1 more source

Milk Modulates the Gastrointestinal Stability of Tick‐Borne Encephalitis Virus: Implications for Alimentary Transmission

open access: yesJournal of Medical Virology, Volume 98, Issue 1, January 2026.
ABSTRACT Tick‐borne encephalitis virus (TBEV) can be transmitted alimentarily through contaminated dairy products, yet the mechanisms by which the virus survives the digestive tract remain poorly understood. In this study, we investigated the stability of TBEV in milk under simulated gastrointestinal conditions.
Martin Machacek   +3 more
wiley   +1 more source

Knowledge, Attitudes and Practices Regarding Livestock Diseases Among Residents of East Gojjam Zone, Amhara Region, Ethiopia

open access: yesVeterinary Medicine and Science, Volume 12, Issue 1, January 2026.
This study reveals gaps in livestock owners’ knowledge and practices regarding disease prevention and control in East Gojjam Zone, Ethiopia, highlighting the need for strengthened veterinary extension services and community education to improve animal health management.
Liuel Yizengaw   +7 more
wiley   +1 more source

Senolytic‐Resistant Senescent Cells Have a Distinct SASP Profile and Functional Impact: The Path to Developing Senosensitizers

open access: yesAging Cell, Volume 25, Issue 1, January 2026.
The SC subtype with a pro‐inflammatory, proapoptotic, tissue‐damaging SASP is susceptible to senolytics. The SC subset not killed by senolytics has a pro‐growth/repair SASP. “Senosensitizers” that induce senolytic‐resistant SCs to be converted into SCs that are susceptible to senolytics could enable removal of relatively silent SCs.
Utkarsh Tripathi   +21 more
wiley   +1 more source

A GmNRF5a–GmCERK1–GmCAK1 module mediates chitin/chitosan‐triggered immune response in soybean

open access: yesJournal of Integrative Plant Biology, Volume 68, Issue 1, Page 257-277, January 2026.
In soybeans, the GmNFR5a‐GmCERK1‐GmCAK1 module regulates immune responses triggered by chitin oligosaccharides and chitosan oligosaccharides from fungal pathogens. This reveals a shared upstream signaling mechanism for distinct microbial patterns and provides valuable genetic targets for improving broad‐spectrum disease resistance in crops.
Guangzheng Sun   +19 more
wiley   +1 more source

A Digital Alert Feedback System (Aged Care Electronic Dashboard Information Tool, ACED‐IT) to Enhance Quality Nursing Care: Participatory Action Research

open access: yesJournal of Clinical Nursing, Volume 35, Issue 1, Page 397-423, January 2026.
ABSTRACT Aims Develop and simulate test a digital alert dashboard drawing from existing data to support nurses, care workers and managers in residential aged care. Design Participatory action research, co‐designing for an Australian 64‐bed residential site.
Kasia Bail   +11 more
wiley   +1 more source

Effects of Oral Macrocyclic Lactone Heartworm Preventatives on Retinal Function and Chromatic Pupillary Light Reflex in Healthy Companion Dogs

open access: yesVeterinary Ophthalmology, Volume 29, Issue 1, January 2026.
ABSTRACT Objective Determine the effect of oral macrocyclic lactone heartworm‐preventative medications on retinal function and chromatic pupillary light reflex (cPLR) in healthy dogs. Animals Studied Cross‐sectional retrospective: 60 dogs (n = 33 females) with heartworm medication administration status and electroretinogram (ERG) data available ...
Ryan G. Hopper   +6 more
wiley   +1 more source

Novel Magnetic Resonance Imaging Findings of Bilaterally Symmetrical Lesions in a Dog With Concomitant Granulomatous Meningoencephalitis and Necrotizing Encephalitis

open access: yesVeterinary Radiology &Ultrasound, Volume 67, Issue 1, January 2026.
ABSTRACT A 3‐year‐old, female neutered Bichon Frise was presented with a 2‐day history of behavioral changes and ataxia. The neurological examination was consistent with diffuse forebrain involvement, with left lateralization. An MRI study identified bilaterally symmetrical T2W/T2 fluid‐attenuated inversion recovery (T2‐FLAIR) hyperintense, T1W ...
Tessa Victoria Procter   +5 more
wiley   +1 more source

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