Results 191 to 200 of about 1,293,795 (280)

Equine tick-borne infections in the Netherlands

open access: yes, 2012
This thesis focuses on the emergence and establishment of equine tick-borne infections in the Netherlands, with particular attention to their diagnosis, clinical relevance and treatment. Four tick-borne agents (Borrelia burgdorferi, Theileria equi, Babesia caballi and Anaplasma phagocytophilum) appeared to be present in horses in the Netherlands, and a
openaire   +2 more sources

High prevalence of a host‐associated Anaplasma lineage in wild coatis (Nasua nasua) from the Brazilian Atlantic Forest

open access: yesMedical and Veterinary Entomology, Volume 40, Issue 4, Page 1087-1092, December 2026.
Anaplasma sp. DNA was detected in 47.9% of free‐ranging coatis (Nasua nasua) sampled in Iguaçu National Park, southern Brazil. Molecular analyses revealed a genetically distinct Anaplasma lineage infecting coatis, differing from Anaplasma strains detected in associated tick populations.
Matheus Dias Cordeiro   +7 more
wiley   +1 more source

Come together: Data sharing to support one health responses to vector‐borne disease threats

open access: yesMedical and Veterinary Entomology, Volume 40, Issue 4, Page 869-878, December 2026.
A One Health framework integrating diverse data across human, animal and environmental sectors is essential for effective surveillance and response is vital for responding to vector‐borne disease risks. Communities adopting global data standards, depositing data in shared repositories, and responsible data use can significantly improve VBD data ...
Francis Windram   +36 more
wiley   +1 more source

Short Report: First Outbreak of Atlantic Rainforest Spotted Fever in North‐Eastern of Brazil—Clinical Features and Eco‐Epidemiological Investigation

open access: yesZoonoses and Public Health, Volume 73, Issue 8, Page 716-724, December 2026.
ABSTRACT Introduction Since 2010, six cases of Atlantic rainforest spotted fever (ARSF) have been confirmed and reported in Brazil, a tick‐borne disease caused by Rickettsia parkeri strain Atlantic rainforest and associated with the tick Amblyomma ovale. So far, none of the cases have been associated with death. One of the cases occurred in 2018 in the
Gabriel Nunes de Oliveira   +13 more
wiley   +1 more source

A Role for Janus Cyclohexyl Ring Motifs in Medicinal Chemistry. Incorporation Into G‐Quadruplex Ligands and Anti‐Trypanosoma brucei Activity

open access: yesChemBioChem, Volume 27, Issue 21, 12 November 2026.
Naphthalene diimide (NDI) cores with peripheral fluorocyclohexyl ring systems are explored binding to G‐quadruplex DNA and were also assayed against the Trypanosoma brucei parasite. The most active compound of the series displayed nanomolar activity and suggested electrostatic interactions between the polarized cyclohexane and G‐Quad DNA.
Josephine M. Stewart   +7 more
wiley   +1 more source

SynNotch Receptors for Visualizing Immunoreceptor Force Transmission and Downstream Signaling In Vivo

open access: yesAdvanced Science, Volume 13, Issue 63, 12 November 2026.
A mechanically activated SynNotch reporter platform enables detection of force transmission through receptors as they mediate immune cell interactions. Targeting CD40 on B cells and TCR on T cells records force‐induced reporter activation across 2D coculture, 3D organoid, and implanted in mice, which also reveal force‐amplification of immune receptor ...
Menglan Li   +9 more
wiley   +1 more source

Targeting the PHB2–ACSL3 Lipid‐Remodeling Axis Overcomes Cisplatin Resistance by Restoring Ferroptosis in Gastric Cancer

open access: yesAdvanced Science, Volume 13, Issue 63, 12 November 2026.
ABSTRACT Platinum‐based chemotherapy resistance remains a major obstacle in gastric cancer (GC) treatment. Through integrated transcriptomic profiling of cisplatin‐resistant xenografts and pharmacogenomic interrogation of the NCI‐60 dataset, we identified Prohibitin‐2 (PHB2) as a previously unrecognized determinant of chemoresistance.
Liang Xu   +10 more
wiley   +1 more source

Modeling the Spread of Crimean Congo Hemorrhagic Fever with Tick Co-feeding. [PDF]

open access: yesBull Math Biol
Kingsley JL   +14 more
europepmc   +1 more source

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