Results 171 to 180 of about 41,007 (259)

Piezo1 Channel Mediates Mechanically Programmable Drug Delivery to Potentiate Intravesical Chemotherapy

Advanced Science, Volume 13, Issue 27, 13 May 2026.
This study utilizes programmable mechanical pressure as a therapeutic enhancer to establish a mechano‐chemotherapy strategy. Controlled pressure activates the mechanosensitive ion channel Piezo1 in bladder cancer, triggering a calcium ion cascade that transiently and reversibly amplifies membrane permeability to chemotherapeutics.
Minghai Ma, Xing Li, Minxuan Jing, Zezhong Yang, Jiale He, Jianpeng Li, Xiao Liang, Yunzhong Jiang, Rou Huang, Yuanquan Zhang, Yuanchun Pu, Jiawei Xiu, Yutong Chen, Kaibo Mi, Pu Zhang, Lei Wang, Jinhai Fan   +16 more
wiley   +1 more source

Borrelia burgdorferi sensu lato Employs Several Escape Mechanisms to Bypass the Human Defense System

European Journal of Immunology, Volume 56, Issue 5, May 2026.
Integrated overview of host defense and immune evasion in Lyme Borreliosis. Bbsl evades immunity through tick saliva‐mediated suppression of innate defenses, TLR2/NOD2‐driven cytokine dysregulation, and interference with JAK/STAT and CIITA‐dependent antigen presentation.
Zara Karami, Hadewych J. M. ter Hofstede, Leo A. B. Joosten   +2 more
wiley   +1 more source

Recent Advances in Natural Polymers‐based Hydrogels for Periodontal Regeneration

Macromolecular Bioscience, Volume 26, Issue 5, May 2026.
Natural polymer‐based hydrogels are emerging as promising biomimetic platforms for periodontal regeneration. This review highlights advances in alginate, collagen, and chitosan hydrogels engineered to modulate inflammation, deliver bioactive agents, and support tissue repair.
João de Freitas Gomes Neto, Tainara de Paula de Lima Lima, Luiza Meurer Brand, Caio Fernando Cardoso Souza, Marcelo Lazzaron Lamers, Pedro L. Granja, Luiz Antonio Pessan, Eduardo Henrique Backes   +7 more
wiley   +1 more source

RNA Modifications: Current Understandings and Future Perspectives

MedComm, Volume 7, Issue 5, May 2026.
Types of RNA modification. We have summarized the currently common types of RNA modifications, including ac4C, m6A, m1A, m5C, m3C, m7G, and ψ, and visually characterized their features through structural formulas. The characteristic structures are marked with a background color different from the background color.
Shiyu Xiao, Tingwen Xiang, Chuan Yang, Xiaohua Wang, Gang Huang, Fei Luo, Zhao Xie, Yueqi Chen   +7 more
wiley   +1 more source

Ferrocene‐Based Sensors for Green Analytical Applications in Environmental, Biomedical, Industrial, and Food Monitoring

ChemistryOpen, Volume 15, Issue 5, May 2026.
Ferrocene derivatives represent a transformative class of molecular sensors, combining exceptional electrochemical stability with tunable redox characteristics that enable precise detection across diverse analytical challenges in environmental, medical, and industrial applications.
Ala'a Al‐Akhras, Asma Ghazzy, Zainab Zakaraya, Ala'a S. Shraim, Obada A. Sibai, Laila Alsabbagh, Deeb Taher   +6 more
wiley   +1 more source

Modeling co-infection of Ixodes tick-borne pathogens.

Mathematical biosciences and engineering : MBE, 2017
Ticks, including the Ixodes ricinus and Ixodes scapularis hard tick species, are regarded as the most common arthropod vectors of both human and animal diseases in Europe and the United States capable of transmitting a large number of bacteria, viruses and parasites.
Yijun Lou, Li Liu, Daozhou Gao
openaire   +2 more sources

Aptamer‐Functionalized Nanocarriers for Bone and Joint Diseases: Engineering Design Rules and Translational Roadmap

Small Science, Volume 6, Issue 5, May 2026.
Aptamer‐functionalized nanocarriers represent a versatile platform for targeted therapy in bone and joint diseases. This review presents five complementary design strategies: free aptamers for soluble targets, bispecific multivalent constructs for enhanced avidity, nanoparticle‐conjugated aptamers for selective tissue accumulation, aptamer‐based ...
Hamdi Al‐Azzani, Djandan Tadum Arthur Vithran, Syeda Sundas Batool, Malek Mohammed Ali Alshabi, Wenhu Zhou, Xiaoqiang Mao   +5 more
wiley   +1 more source

Sero‐Epidemiology and Molecular Detection of Bluetongue Virus in Goats in Bangladesh

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
The first large‐scale study in Bangladesh confirmed bluetongue virus infection in goats through combined c‐ELISA and nested RT‐PCR approaches, revealing high seroprevalence and identifying key management‐related risk factors. ABSTRACT Background Bluetongue (BT) is an arthropod‐transmitted, non‐contagious viral disease of domestic ruminants caused by ...
Md Habibur Rahman, Md Nurul Haque, Md Zulfekar Ali, Lutfun Naher, Md Zakir Hassan, Sadek Ahmed   +5 more
wiley   +1 more source

Improving Molecular Detection of Tick-Borne Pathogens in Citizen-Collected Ticks. [PDF]

Pathogens
Matucci A, Scarso S, Da Rold G, Obber F, Marzoli F, Ragusa A, Formenti F, Treggiari D, Mori A, Mazzi C, Tedesco A, Sponga P, Bertoli G, Moro L, Castilletti C, Citterio CV, Buonfrate D, Gobbi FG, Perandin F, Piubelli C.   +19 more
europepmc   +1 more source

Successful Management of Septic Splenitis in an Abyssinian Cat

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
A 3.5‐year‐old female neutered Abyssinian with pyrexia of unknown origin and splenomegaly was diagnosed with septic splenitis. Complete resolution of clinical signs followed splenectomy and antibiotic treatment with pradofloxacin. Septic splenitis, although uncommon, should be considered as a differential diagnosis in patients with splenomegaly and ...
Martina Vecín Sancho, Perrine Henry, Mica Taylor, Catherine Davidson, María Lázaro Muñoz, Efa Llewellyn, Maša Vilfan, Paola Cazzini, Linda Morrison, Kelly Blacklock, Danièlle Gunn‐Moore   +10 more
wiley   +1 more source