Results 51 to 60 of about 20,744 (219)
Advanced Science, EarlyView.Host‐specific compatibility between RNF138‐like proteins and flavivirus NS5 determines NS5 stability. Mammalian RNF138 but not arthropod homologs recognizes and induces conserved NS5/RdRp K48‐linked ubiquitination and proteasomal degradation, thereby restricting viral replication. Ectopic RNF138 in mice attenuates TBEV‐induced pathogenesis. (Created in
Jialiang Sun +6 more
wiley +1 more source
Fatal Tick-Borne Encephalitis in Unvaccinated Traveler from the United States to Switzerland, 2022
Emerging Infectious DiseasesWe report an unvaccinated traveler from the United States who contracted fulminant fatal tick-borne encephalitis while visiting Switzerland. Climate changes and international travel are intensifying tick exposure for unvaccinated persons. The increasing
Chiara Scotti +7 more
doaj +1 more source
Advanced Science, EarlyView.Integrated clinical and mechanistic analyses identify GALNT7 as a ferroptosis‐suppressive regulator associated with immunotherapy resistance in non‐small cell lung cancer. GALNT7 depletion promotes lipid peroxidation, mitochondrial dysfunction, and ferroptosis, enhances CD8+ T‐cell activation and IFN‐γ production, and sensitizes tumors to PD‐1 blockade,
Jiadi Gan +11 more
wiley +1 more source
A New Tick-borne Encephalitis-like Virus Infecting New England Deer Ticks, Ixodes dammini
Emerging Infectious Diseases, 1997 To determine if eastern North American Ixodes dammini, like related ticks in Eurasia, maintain tick-borne encephalitis group viruses, we analyzed ticks collected from sites where the agent of Lyme disease is zoonotic.
Sam R. Telford +6 more
doaj +1 more source
Advanced Science, EarlyView.Radiotherapy triggers LTβR N‐glycosylation, enhancing its overall protein stability and nuclear retention. This accumulation drives TRIM28‐mediated PCBP2 SUMOylation, suppressing pyroptosis and conferring gastric cancer radioresistance. Therapeutically, a targeted nanoplatform (cRGD‐Lipo@EMD) effectively disrupts this regulatory axis, offering a highly
Weijie Zang +8 more
wiley +1 more source
Tick-borne Encephalitis Virus in Horses, Austria, 2011
Emerging Infectious Diseases, 2013 An unexpectedly high infection rate (26.1%) of tick-borne encephalitis virus (TBEV) was identified in a herd of 257 horses of the same breed distributed among 3 federal states in Austria.
James O. Rushton +5 more
openaire +4 more sources
npj Vaccines, 2017 Tick-borne encephalitis: One vaccine protects against multiple flaviviruses Prior exposure to tick-borne encephalitis virus confers immunity to distinct, but genetically related, significant human pathogens.
Alexander J. McAuley +11 more
doaj +1 more source
Analysis of synonymous codon usage bias, nucleotide and amino acid composition in 13 species of Flaviviridae [PDF]
Journal of Cell and Molecular Research, 2011 Flaviviridae are viruses that cause several diseases including Dengue fever, Japanese encephalitis, Murray Valley encephalitis, Tick-borne encephalitis, West Nile encephalitis, Yellow fever and Hepatitis C Virus Infection.
Fatemeh Moosawi +2 more
doaj +1 more source
Diversity of RNA viruses of three dominant tick species in North China
Frontiers in Veterinary Science, 2023 BackgroundA wide range of bacterial pathogens have been identified in ticks, yet the diversity of viruses in ticks is largely unexplored.MethodsHere, we used metagenomic sequencing to characterize the diverse viromes in three principal tick species ...
Tong Qin +6 more
doaj +1 more source
Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS) in Glioblastoma
Advanced Science, EarlyView.ABSTRACT Glioblastoma (GBM) remains one of the most challenging brain malignancies due to the restrictive nature of the blood–brain barrier (BBB), which severely limits effective drug and gene delivery. To overcome this, we introduce Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS), a modular platform that enables safe ...
Gulsah Erel‐Akbaba +25 more
wiley +1 more source