Results 91 to 100 of about 13,963 (192)

Impact of climate on Australian, non‐Vector‐borne infectious animal diseases: A scoping review

Australian Veterinary Journal, EarlyView.
Changes to Australia's climate continue to be increasingly relevant for human, animal and planetary health, and have far‐reaching impacts on disease emergence and food security. There is a deficit of knowledge in Australia around how climatic conditions are affecting infectious animal diseases, beyond the more obvious spatial distribution changes of ...
G Terry, MP Ward
wiley   +1 more source

Ezh2 Inhibits the Differentiation of Short‐Lived Effector CD8+ T Cells and Promotes T Cell‐Dependent Antitumor Immunity

Cancer Science, EarlyView.
The antitumor immune response is attenuated in T cell‐specific Ezh2 knockout mice. ABSTRACT Appropriate regulation of the differentiation balance between effector CD8+ T cells and memory CD8+ T cells is crucial for an appropriate immune response. We previously reported that the tumor suppressor menin suppresses the differentiation of CD8+ T cells into ...
Kenji Takagi, Junpei Suzuki, Yuko Matsuoka, Makoto Kuwahara, Taro Oshikiri, Masakatsu Yamashita   +5 more
wiley   +1 more source

Structural insights into tyrosine sulfation of CCR5 by human tyrosylprotein sulfotransferase‐1

The FEBS Journal, EarlyView.
Structural analysis of human tyrosylprotein sulfotransferase‐1 (hTPST1) bound to a CCR5 N‐terminal peptide reveals how hTPST1 recognizes the Tyr3 sulfation site. Structure‐guided models of additional CCR5 sulfation states and full‐length assemblies provide a framework for understanding CCR5 tyrosine sulfation, a post‐translational modification relevant
Shinnosuke Tanaka, Hirai Asano, Kota Toyoda, Toshiaki Nishiyori, Hidetaka Kojo, Kazuto Kiyomatsu, Katsuhisa Kurogi, Yoichi Sakakibara, Etsuko Nishimoto, Takamasa Teramoto, Yoshimitsu Kakuta   +10 more
wiley   +1 more source

A scoping review of the acceptability, feasibility and effectiveness of opt‐out blood‐borne virus (BBV) testing in secondary healthcare settings, in the UK and similar settings, using APEASE criteria

HIV Medicine, EarlyView.
Abstract Background Earlier diagnosis of blood‐borne viruses (BBVs)—HIV, hepatitis B (HBV) and hepatitis C (HCV)—remains a significant public‐health focus. Opt‐out testing in secondary healthcare settings can improve early diagnosis and linkage to care as part of BBV transmission elimination targets.
Becky Metcalfe, Karen J. Maxwell, Kirsten Trayner, Max Wilkinson, Sharon Hutchinson, Claudia Estcourt, Alison J. Rodger   +6 more
wiley   +1 more source

Beyond the Kidney and Lung: Cutaneous and Mucosal Clues to Human Hantavirus Disease

International Journal of Dermatology, EarlyView.
Rodent exposure and aerosolized excreta can lead to hantavirus infection with systemic endothelial injury and capillary leak, resulting in thrombocytopenia and syndromes such as HPS/HCPS and HFRS/NE. Early dermatologic and mucosal findings, including flushing, conjunctival injection, petechiae/purpura, and mucosal bleeding, may provide important clues ...
Giuseppe Gallo, Pietro Quaglino, Simone Ribero   +2 more
wiley   +1 more source

Social Media Is a Threat for Democracy! A Political Perspective for Analysing and Diminishing Harm

Journal of Management Studies, EarlyView.
Abstract Social media platforms, once hailed as potential champions of dialogue, have evolved into commodified spaces in which their business models incentivize hate speech, misinformation, polarization, and the political fragmentation of society, benefiting corporate and political elites while eroding democracy.
Itziar Castelló, Elanor Colleoni, Andreas Georg Scherer, Hannah Trittin‐Ulbrich   +3 more
wiley   +1 more source

Generics favor stability

Mind &Language, EarlyView.
Humans seek to predict, explain, and control their environments. Generalizations—like those expressed by “children like candy” and “cigarettes cause cancer”—provide one resource to facilitate these tasks. We develop a proposal tying the acceptability judgments of generics to the psychological functions of generalizations.
Katherine Ritchie, Ny Vasil
wiley   +1 more source

Come together: Data sharing to support one health responses to vector‐borne disease threats

Medical and Veterinary Entomology, EarlyView.
A One Health framework integrating diverse data across human, animal and environmental sectors is essential for effective surveillance and response is vital for responding to vector‐borne disease risks. Communities adopting global data standards, depositing data in shared repositories, and responsible data use can significantly improve VBD data ...
Francis Windram, Sarah Kelly, Stanislav Modrak, Isabelle Dietrich, Corrado Minetti, Karen L. Mansfield, Frederik Seelig, Adam M. Fisher, Maisie Vollans, Nina Billows, Fahad Ahmed, Marta Shocket, Susana Campino, Scott Tytheridge, Sara L. Gandy, Estela Gonzalez, Jolyon M. Medlock, Matthew Baylis, Grant L. Hughes, David A. Ewing, Bethan V. Purse, Georgia Kirby, Clare Strode, Arran J. Folly, David Starns, Heather Ferguson, Simon Smith‐Mullally, Helen Roberts, Christopher M. Jones, Hannah Rose Vineer, Marion England, Christopher Sanders, Samraat Pawar, William D. Pearse, Steven M. White, Robert T. Jones, Lauren J. Cator   +36 more
wiley   +1 more source

Virome specific to tick genus with distinct ecogeographical distribution

Microbiome
Background The emergence of tick-borne pathogens poses a serious threat to both human and animal health. There remains controversy about virome diversity in relation to tick genus and ecogeographical factors.
Di Tian, Run-Ze Ye, Yu-Yu Li, Ning Wang, Wan-Ying Gao, Bai-Hui Wang, Zhe-Tao Lin, Wen-Jie Zhu, Qiu-Shi Wang, Ya-Ting Liu, Hua Wei, Yi-Fei Wang, Yi Sun, Xiao-Yu Shi, Na Jia, Jia-Fu Jiang, Xiao-Ming Cui, Tick Genome and Microbiome Consortium (TIGMIC), Wu-Chun Cao, Zhi-Hong Liu   +19 more
doaj   +1 more source

Metagenomic evidence of viral secretion from tick salivary glands to saliva: implications for potential horizontal transmission

Ticks and Tick-Borne Diseases
Ticks transmit diverse viral pathogens to hosts during blood-feeding via saliva secretion. This study characterized viral compositions in salivary glands and saliva from adults of four tick species (Ixodes persulcatus, Rhipicephalus microplus ...
Jun Ni, Liyan Fu, Jian Xiao, Chenxuan Li, Xiaoli Wu, Zhi Yuan, Jun Wang, Shuang Tang, Fei Deng, Shu Shen   +9 more
doaj   +1 more source