Results 31 to 40 of about 143,398 (260)

Morphology of the Preimaginal Stages of Lasioptera donacis Coutin (Diptera: Cecidomyiidae), a Candidate Biocontrol Agent for Giant Arundo Cane

Psyche: A Journal of Entomology, 2015
The larval stages of Lasioptera donacis Coutin consist of three instars which develop within the mesophyll of the leaf sheaths of Arundo donax (L.) (Poaceae). The larvae feed aggregatively on mycelia of an ambrosia fungus.
Donald B. Thomas, John A. Goolsby
doaj   +1 more source

Replication enhancer elements within the open reading frame of tick-borne encephalitis virus and their evolution within the Flavivirus genus [PDF]

, 2011
We provide experimental evidence of a replication enhancer element (REE) within the capsid gene of tick-borne encephalitis virus (TBEV, genus Flavivirus).
I. M. Jones, Gould, EA, Tuplin, Andrew, Gould, E. A., A. Buckley, E. A. Gould, A. Tuplin, Tuplin, A., Jones, I. M., Jones, I. M. (Ian M.), Buckley, A., Gould, E., T. S. Gritsun, Jones, IM, Gritsun, T. S., Tuplin, A, Evans, DJ, Evans, David J., Gritsun, TS, D. J. Evans, Evans, D. J., Buckley, A   +21 more
core   +1 more source

A longitudinal transcriptomic analysis from unfed to post-engorgement midguts of adult female Ixodes scapularis

Scientific Reports, 2023
The hematophagy behavior has evolved independently several times within the Arthropoda phylum. Interestingly, the process of acquiring a blood meal in ticks is considerably distinct from that observed in other blood-feeding arthropods.
Stephen Lu, Larissa A. Martins, Jan Kotál, José M. C. Ribeiro, Lucas Tirloni   +4 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Emerging tick-borne pathogens in the Nordic countries: A clinical and laboratory follow-up study of high-risk tick-bitten individuals [PDF]

, 2020
Despite the presence of several microorganisms, other than Borrelia burgdorferi sensu lato (Bbsl) and TBE virus, in Ixodes ricinus ticks from the Nordic countries, data is lacking on their pathogenic potential in humans.
Lindgren, Per-Eric, Krogfelt, Karen Angeliki, Krogfelt, Karen Angeliki,, Henningsson, A. J., Krogfelt, K. A., Wilhelmsson, Peter,, Nordberg, M., Sværke Jørgensen, Charlotte, Forsberg, P., Nordberg, Marika,, Sjowall, J., Henningsson, Anna J.,, Jorgensen, Charlotte Svaerke, Forsberg, Pia,, Henningsson, Anna J., Lindgren, P. E., Ocias, Lukas Frans,, Wilhelmsson, Peter, Lindgren, Per-Eric,, Nordberg, Marika, Forsberg, Pia, Sjöwall, Johanna,, Ocias, Lukas Frans, Jorgensen, Charlotte Svaerke,, Jonsson Henningsson, Anna, Sjöwall, Johanna, Wilhelmsson, P.   +26 more
core   +1 more source

Flaviviruses in AntiTumor Therapy

Viruses, 2023
Oncolytic viruses offer a promising approach to tumor treatment. These viruses not only have a direct lytic effect on tumor cells but can also modify the tumor microenvironment and activate antitumor immunity.
Alina S. Nazarenko, Mikhail F. Vorovitch, Yulia K. Biryukova, Nikolay B. Pestov, Ekaterina A. Orlova, Nickolai A. Barlev, Nadezhda M. Kolyasnikova, Aydar A. Ishmukhametov   +7 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Reassociation kinetics-based approach for partial genome sequencing of the cattle tick, Rhipicephalus (Boophilus) microplus [PDF]

, 2010
Background: The size and repetitive nature of the Rhipicephalus microplus genome makes obtaining a full genome sequence fiscally and technically problematic. To selectively obtain gene-enriched regions of this tick's genome, Cot filtration was performed,
Matthew Bellgard, Peterson, D., Appolinaire Djikeng, Nene, Vishvanath M., Felix D Guerrero, Guerrero, F.D., Caler, E., Moolhuijzen, Paula, Vishvanath M Nene, Elisabet Caler, Djikeng, Appolinaire, Nene, V.M., Paula Moolhuijzen, Moolhuijzen, P., Shelby Bidwell, Bellgard, M., Daniel G Peterson, Nene, V., Djikeng, A., Guerrero, F., Peterson, D.G., Bidwell, S.   +21 more
core   +1 more source

A novel combination of fipronil and permethrin (Frontline Tri-Act®/Frontect®) reduces risk of transmission of Babesia canis by Dermacentor reticulatus and of Ehrlichia canis by Rhipicephalus sanguineus ticks to dogs

Parasites & Vectors, 2015
Background The ability of Frontline Tri-Act®/Frontect®, a topical ectoparasiticide containing fipronil and permethrin for dogs, to prevent the transmission of Babesia canis as well as Ehrlichia canis was evaluated by infesting dogs with infected vector ...
Frans Jongejan, Christa de Vos, Josephus J. Fourie, Frederic Beugnet   +3 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source