Results 51 to 60 of about 124,001 (286)

Voltage‐Reconfigurable Magneto‐Ionic Nanolayers in Dot Arrays for Probabilistic, Materials‐Engineered Security Primitives

Advanced Science, EarlyView.
A magneto‐ionic security‐by‐materials‐design strategy exploits voltage‐driven N3– migration in selectively contacted FeCoN dots, creating reconfigurable sub‐15 nm ferromagnetic sublayers with deterministic and/or probabilistic (single‐domain↔vortex) states, voltage‐tunable probabilities and fully stochastic orientation/chirality.
Irena Spasojevic, Federica Celegato, Alessandro Magni, Paola Tiberto, Jordi Sort   +4 more
wiley   +1 more source

Circulating microRNA profiles associated with tick bite and debilitating symptom complexes attributed to ticks (DSCATT)

Scientific Reports
Tick bites in Australia are associated with a poorly understood syndrome known as Debilitating Symptom Complexes Attributed to Ticks (DSCATT), however, the underlying biological mechanisms remain unclear.
Ryan J. Farr, Carlos H. M. Rodrigues, Siobhon Egan, Jenny Su, Amanda D. Barbosa, Michelle Long, Jill Austen, Wenna Lee, Alexander W. Gofton, Andrew Ratchford, Brian Burns, Miles Beaman, Allen C. Cheng, Helen M. Faddy, Justine O’Donovan, Roy Hall, Marjorie Collins, Una M. Ryan, John Stenos, Stephen Graves, Charlotte L. Oskam, Peter J. Irwin, Cameron R. Stewart   +22 more
doaj   +1 more source

Skin ulcer and maculopapular rash with inguinal lymph node enlargement: a case report of a 46-year-old female patient from north-eastern Poland with Rickettsia spp. and Francisella tularensis co-infection

Central European Journal of Immunology
North-eastern Poland is an endemic region for tick-borne diseases, especially Lyme disease and tick-borne encephalitis. However, less common diseases such as rickettsiosis and tularemia may occur after a tick bite.
Karol Borawski, Anna Lebensztejn, Piotr Czupryna, Maciej Kondrusik, Sławomir Pancewicz, Justyna Adamczuk, Tomasz Chmielewski, Anna Moniuszko-Malinowska   +7 more
doaj   +1 more source

Senkyunolide I Inhibits mtDNA‐cGAS‐STING Signaling in Macrophages via Targeting VDAC1 Oligomerization to Attenuate Ulcerative Colitis

Advanced Science, EarlyView.
In macrophages, senkyunolide I (SEI) directly targets the K12 residue of VDAC1 to inhibit its stress‐induced oligomerization, a critical upstream event that effectively prevents mitochondrial DNA release and subsequent cGAS‐STING pathway activation.
Zhiming Ye, Yihang Huang, Bohao Han, Lei Zhang, Can Yu, Yang Yang, Bing Liu, Yongping Jian, Zhixiang Xu, Cheng Zeng   +9 more
wiley   +1 more source

Trends in incidence of tick bites and physician-reported early and late Lyme borreliosis in the Netherlands

Ticks and Tick-Borne Diseases
Lyme borreliosis (LB) is a prevalent vector-borne disease in Europe. Untreated, it can cause severe complications, with some patients experiencing persistent symptoms post-treatment.
Oda E. van den Berg, Margriet G. Harms, Anna D. Tulen, Vanessa D. Brown, Jan van de Kassteele, Agnetha Hofhuis, Cees C. van den Wijngaard   +6 more
doaj   +1 more source

Isocyanate‐Modified Melatplatin(IV) Enhances Antitumor Efficacy via TCF4/COL6A3‐Mediated Extracellular Matrix Remodeling and cGAS‐STING Pathway Activation in Bladder Cancer

Advanced Science, EarlyView.
A series of melatonin‐conjugated platinum(IV) prodrugs was functionalized with isocyanate chains (compounds 5‒12). MP‐12C (compound 11) was identified as the lead candidate, with optimal potency and safety. MP‐12C exhibited greater efficacy than cisplatin by increasing intracellular uptake, reshaping the extracellular matrix, activating the cGAS‐STING ...
Linhui Wang, Xiaomeng Liu, Tao Zhu, Zirun Su, Ruiping Liu, Zhe Li, Kaixuan Du, Kaipeng Jia, Chong Fu, Yuda Lin, Zihan Xue, Zhe Zhang, Chong Shen, Yunkai Qie, Zhouliang Wu, Zhiheng Liu, Kangkang Liu, Jingyuan Xu, Hailong Hu   +18 more
wiley   +1 more source

Tick Bite: What To Do [PDF]

Ticks bites can make people sick. Below are some steps that you can take after a tick bite to reduce your chances of getting sick and how to get treatment promptly if you do get sick.www.cdc.gov/ticks/CS303879-AFS_TickBite.pdfRemove the tick as soon as ...

core   +4 more sources

Factors driving tick bite risk during a high-density outdoor activity

Ticks and Tick-Borne Diseases
Understanding the factors driving individual exposure to tick bites is essential for predicting tick-borne disease risk. We analyzed data from a 6-day international orienteering competition held in July 2018 in the forests of Moselle, France, involving ...
Laure Bournez, Pascale Frey-Klett, Jonas Durand   +2 more
doaj   +1 more source

First report of African tick-bite fever in a South American traveler

SAGE Open Medical Case Reports, 2018
We report a clinical case of African tick-bite fever in a Brazilian traveler right after his return from South Africa. Definitive diagnosis was supported by seroconversion between acute-phase and convalescent-phase serum samples, detection of rickettsial
Rodrigo N Angerami, Felipe S Krawczak, Fernanda A Nieri-Bastos, Fabiana Santos, Claudio Medorima, Mariângela Ribeiro Resende, Marcelo B Labruna   +6 more
doaj   +1 more source

Decoding Biomolecular Phase Separation: From Physiological Roles to Pathological Mechanisms and Therapeutic Biomaterials Design

Advanced Science, EarlyView.
This review systematically elaborates on the mechanisms underlying physiological regulation and pathological dysregulation of biomolecular phase separation. It also summarizes advances in phase‑separation‑targeted therapeutic strategies and the design of functional biomaterials inspired by this process.
Jiawei Zhu, Jingbo Dong, Qiufang Gong, Xuejiao Song, Zhifa Shen, Chao Liang   +5 more
wiley   +1 more source