Results 161 to 170 of about 145,686 (240)

Global gene expression profiling of virulent and attenuated strains of Ehrlichia ruminantium: Toward the comprehension of pathogenesis [PDF]

, 2014
Emboule, Loïc, Gordon, Jonathan, Lebrigand, Kevin, Lefrançois, Thierry, Marcelino, Isabel, Mari, Bernard, Martinez, Dominique, Meyer, Damien, Pinarello, Valérie, Pruneau, Ludovic, Sheikboudou, Christian, Vachiery, Nathalie, Viari, Alain   +12 more
core  

Recent Advances in mRNA Delivery Systems for Cancer Therapy

Advanced Science, EarlyView.
This review systematically investigates the applications of mRNA therapy in cancer treatment, with particular emphasis on nonviral delivery systems, targeting strategies, stimulus‐responsive systems, and local delivery methods. Concluding with a meticulous evaluation, the review sheds light on the prevailing challenges while illuminating promising ...
Zheng Zhang, Ya‐Nan Fan, Si‐Qi Jiang, Ya‐Jing Ma, Yao‐Ru Yu, Yu‐Xin Qing, Qian‐Ru Li, Yi‐Lin Liu, Song Shen, Jun Wang   +9 more
wiley   +1 more source

Surveillance of Tick-Borne Pathogens in Ticks from Humans in the Province of Verona, Italy (2018-2022): A Prospective Study. [PDF]

Microorganisms
Moro L, Da Rold G, Beltrame A, Formenti F, Mazzi C, Ragusa A, Scarso S, Drigo I, Degani M, Piubelli C, Citterio CV, Perandin F.   +11 more
europepmc   +1 more source

PABPN1 Couples the Polyadenylation and Translation of Maternal Transcripts to Mouse Oocyte Meiotic Maturation

Advanced Science, EarlyView.
This study reveals that cytoplasmic PABPN1 is essential for mouse oocyte meiotic maturation by coordinating polyadenylation, translation, and degradation of maternal mRNAs. Pabpn1 knockout disrupts CDK1 activation, spindle formation, and chromosome alignment by impairing maturation‐promoting factor (MPF) regulation and BTG4‐mediated deadenylation ...
Xing‐Xing Dai, Yu‐Ke Wu, Shuai‐Bo Pi, Feng‐Jie Hu, Yun‐Wen Wu, Hang Qi, Zhiyi Li, Zhi‐Yan Jiang, Long‐Wen Zhao, Heng‐Yu Fan   +9 more
wiley   +1 more source

Differential impact of spotted fever group <i>rickettsia</i> and anaplasmosis on tick microbial ecology: evidence from multi-species comparative microbiome analysis. [PDF]

Front Microbiol
Wang JQ, Yu T, Qiu HY, Ji SW, Xu ZQ, Cui QC, Li HF, Liang WF, Feng S, Fu CT, Gao X, Han ZZ, Tian WN, Li JX, Xue SJ.   +14 more
europepmc   +1 more source

A Self‐Assembling LYTAC Mediates CTGF Degradation and Remodels Inflammatory Tumor Microenvironment for Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
A CTGF‐LYTAC nanoplatform is developed to selectively degrade connective tissue growth factor (CTGF) in triple‐negative breast cancer (TNBC), inhibiting TGF‐β signaling and cell interactions in the tumor microenvironment (TME). This strategy effectively suppresses tumor growth and metastasis, outperforming antibody‐based therapy.
Jia‐Yi Lin, Ye Wu, Xiao‐Hui Liang, Min Tang, Xin Sun, Sheng‐Xin Lu, Jin‐Mei Jin, Xin Guo, Bei Wang, Hong‐Zhuan Chen, Wei‐Dong Zhang, Xin Luan   +11 more
wiley   +1 more source

Genetic diversity and expanded epidemic area of novel tick-borne pathogen wetland virus in ticks, wild and domestic animals, and patient in China. [PDF]

Emerg Microbes Infect
Yuan HX, Lv XL, Zhang MQ, Si GQ, Zhao ZJ, Han XH, Hou ZJ, Cui N, Zhang L, Ma YD, Wu SQ, Yang X, Mu HZ, Peng C, Chen M, Bao PT, Li H, Han SZ, Zhang XA, Liu W.   +19 more
europepmc   +1 more source

Natural Toolbox–Chemical Engineering Aspect and High‐Value Applications of Janus Cellulose Nanomaterials

Advanced Science, EarlyView.
The Tai Ji symbol from China represents the co‐existence of two opposite substances, similar to quantum entanglement. The term Janus comes from ancient Roman religion and mythology. Janus, the god of beginnings, transitions, etc., has two faces, symbolizing duality. Janus cellulose nanomaterials show structural duality.
Yu Zhao, Shengjie Wang, Zongchen Wei, Shiming Qiu, Guofu Zhou, Jr‐Hau He, Xuezhu Xu   +6 more
wiley   +1 more source

Cattle Zoonotic and Non-Zoonotic Tick-Borne Pathogens in Europe-A Retrospective Analysis of the Past 15 Years. [PDF]

Animals (Basel)
Hoffman D, Dreghiciu IC, Oprescu I, Imre M, Florea T, Plesko A, Morariu S, Ilie MS.   +7 more
europepmc   +1 more source

Breaking the Recycling Bottleneck of Thermosets via Bio‐Tailoring Technology

Advanced Science, EarlyView.
Recyclable thermosets are achieved by using the Bio‐Tailoring technology. The Bio‐Tailoring technology effectively addresses the longstanding paradox surrounding the recyclable and reuse properties of thermosets, breaking the recycling bottleneck of thermosets.
Jinping Yu, Huan Wang, Yang Xu, Boutrous Wemegah, Yang Lan, Jing Li, Li Yang, Guanjun Chang   +7 more
wiley   +1 more source