Results 241 to 250 of about 82,246 (321)

DON‐Loaded Nanodrug‐T Cell Conjugates With PD‐L1 Blockade for Solid Tumor Therapy

open access: yesAdvanced Science, EarlyView.
This study establishes DON‐loaded T cell‐nanodrug conjugates with PD‐L1 blockade, creating a synergistic system. As a glutamine antagonist, sustained DON release enhances T‐cell endurance and infiltration by promoting memory differentiation and upregulating adhesion and motility genes, while PD‐L1 blockade alleviates immunosuppression and directs T ...
Xin Yang   +13 more
wiley   +1 more source

First detection of Amblyomma lepidum (Dönitz, 1909) in Zimbabwe. [PDF]

open access: yesExp Appl Acarol
Smit A   +5 more
europepmc   +1 more source

Cartilage‐Penetrating Framework Nucleic Acid Nanoparticles Ameliorate Osteoarthritis by Promoting Drug Delivery and Chondrocyte Uptake

open access: yesAdvanced Science, EarlyView.
Based on the poor cartilage penetration of tFNA, a novel tFNA‐2WL with excellent cartilage permeability and perfect chondrocyte endocytosis properties is designed and fabricated. As a result, tFNA‐2WL has a nearly seven‐fold increase in the penetration depth into the cartilage, with the same excellent cell entry properties as tFNA.
Kui Huang   +9 more
wiley   +1 more source

Generation of a High‐Precision Whole Liver Panorama and Cross‐Scale 3D Pathological Analysis for Hepatic Fibrosis

open access: yesAdvanced Science, EarlyView.
Using the MOSTtechnology and whole‐liver Nissl staining method, a multi‐structural 3D pathological panorama of liver fibrosis is obtained. The damaged sinusoids, steatotic hepatocytes, and collagen deposition are all concentrated in pericentral areas.
Xiaochuan Zhang   +13 more
wiley   +1 more source

Active surveillance for Theileria orientalis and the invasive Asian longhorned tick (Haemaphysalis longicornis) in three Missouri beef herds. [PDF]

open access: yesPLoS One
Ierardi RA   +9 more
europepmc   +1 more source

Toward Green Processing of Perovskite Solar Cells: Protic Ionic Liquids Enable Water‐ and Alcohol‐Based MAPbI3 Precursors Inks for Slot‐Die Coating

open access: yesAdvanced Energy Materials, EarlyView.
This work represents the first report of a water‐based green ink formulation for one‐step thin film coating of halide perovskite semiconductors at room‐temperature conditions by slot‐die coating, highlighting its potential for sustainable commercial manufacturing. Optimization of the solvent mixture of water (H2O) isopropanol (IPA) and the protic ionic
Feray Ünlü   +12 more
wiley   +1 more source

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