Results 251 to 260 of about 291,682 (345)

CLinNET: An Interpretable and Uncertainty‐Aware Deep Learning Framework for Multi‐Modal Clinical Genomics

Advanced Science, EarlyView.
Identifying disease‐causing genes in neurocognitive disorders remains challenging due to variants of uncertain significance. CLinNET employs dual‐branch neural networks integrating Reactome pathways and Gene Ontology terms to provide pathway‐level interpretability of genomic alterations.
Ivan Bakhshayeshi, Mohammad Mahdi Hosseini, Ahmadreza Argha, Roxana Zahedi, Nigel H. Lovell, Hamid Alinejad‐Rokny   +5 more
wiley   +1 more source

Evaluation of the efficacy of preparation «AcaroKILL» against ixodic ticks

, 2020
О. В. Федорова, Yu. Prykhodko, O. V. Mazannyy, О. В. Нікіфорова, P. Liulin   +4 more
openalex   +1 more source

Variety of Bacterial Pathogens in Ticks Removed from Humans, Northeastern China. [PDF]

Microorganisms
Su XL, Ye JL, Zhang MZ, Wang YF, Sun Y, Wu YF, Bian C, Yao NN, Zheng YC, Jiang JF, Zheng XM, Cao WC.   +11 more
europepmc   +1 more source

Host‐Directed Antiviral Activity of SB2960 Through Selective Induction and Remodeling of Stress Granules

Advanced Science, EarlyView.
Amid the ongoing threat of emerging viral pathogens, host‐directed antivirals offer a strategy to overcome viral mutation and drug resistance. SB2960, a small‐molecule inducer of stress granules (SGs), exhibits potent broad‐spectrum antiviral activity with minimal cytotoxicity.
Wan Gi Byun, Sumin Son, JinAh Lee, Minha Lee, Meehyun Ko, Songrui Zhao, Ju Hee Kim, Kannan Vaithegi, Ji Hoon Kwon, Jung Ho Lee, Sangeun Jeon, Dawon Yi, Peng Zou, Seungtaek Kim, Seung Bum Park   +14 more
wiley   +1 more source

Lethal Case of Bourbon Virus Leading to Shock and ECMO Utilization. [PDF]

Case Rep Infect Dis
Mitchell A, Gessouroun A, Atrouni WE, Kubat R, Almoghrabi O, Vorhies M, Flynn B.   +6 more
europepmc   +1 more source

WDR5‐H3K4me3 Epigenetic Axis Promotes TRMT6‐Dependent tRNA M1A Modification to Facilitate Triple‐Negative Breast Cancer Progression by Suppressing Ferroptosis

Advanced Science, EarlyView.
Upregulated TRMT6 forms aberrant hypermethylation of a specific tRNA pool and serves as a predictor of poor prognosis in TNBC. This m1A modification in tRNAs enhances translation of FTH1 and FTL, reducing the pool of bioavailable Fe2⁺. Reduced Fe2+ availability impairs RSL3‐induced lipid peroxidation and tumor progression.
Yuqing Lei, Xue Wang, Jiahe Liu, Zixu Niu, Jiaqi Hua, Qian Guo, Dan Du, Yuanchang Zhu, Fucheng He, Mingxia Zhou, Hongle Li, Jing He, Jun Li   +12 more
wiley   +1 more source

<i>Anaplasma phagocytophilum</i> ecotype distribution and zoonotic potential in questing and feeding <i>Ixodes ricinus</i> from Germany. [PDF]

Curr Res Parasitol Vector Borne Dis
Springer A, Angulo Mora D, Jordan D, Strube C.   +3 more
europepmc   +1 more source

Functional, Pharmacogenomic, and Immune Landscapes of Long Non‐Coding RNAs in Cancer

Advanced Science, EarlyView.
A systematic analysis of 33 cancer types reveals widespread associations between lncRNAs and cancer pathways, drug responses, immune features, and immunotherapy outcomes. The study identifies key lncRNAs linked to therapeutic response and adverse events and introduces PILNC, an interactive web portal for exploring the functional, pharmacogenomic, and ...
Runhao Wang, Mei Luo, Yuan Liu, Jingwen Yang, Yamei Chen, Chengxuan Chen, Lifei Ma, Stephanie Ding, James Wengler, Yong Zang, Bora Lim, Wenbo Li, Liuqing Yang, Chunru Lin, Lixia Diao, Leng Han   +15 more
wiley   +1 more source

BURDEN, SEASONALITY, SEX RATIO AND PREFERRED SITES OF TICKS OF PUBLIC HEALTH IMPORTANCE ON CATTLE FOUND AT AMANSEA, ANAMBRA STATE NIGERIA

, 2015
Ikpeze, Eneanya C.I., Onyido
openalex   +2 more sources

Infection-Mediated Shifts in the Microbial Communities of Deer-Fed <i>Ixodes scapularis</i> Ticks. [PDF]

Microorganisms
Tawidian P, Tucker BJ, Zembsch TE, Ip HS, Bartholomay LC.   +4 more
europepmc   +1 more source