Endothelium-independent vasorelaxation by ticlopidine and clopidogrel in rat caudal artery.
OBJECTIVES: Thienopyridines are prodrugs currently used as anti-aggregating agents. The aim of this study was to determine if these compounds might have vascular activity independent of hepatic bioactivation.
Guglielmina Froldi +9 more
core +1 more source
Influence of methadone on clopidogrel in addicts on methadone maintenance therapy
Background: Clopidogrel is a prodrug that converts in the liver to an active thiol metabolite, which irreversibly inhibits the platelet P2Y12 adenosine diphosphate receptor.
Ferigol Fallah +4 more
doaj
A drug interaction study between ticlopidine and cyclosporin in heart transplant recipients.
International audienceOBJECTIVES: Previous uncontrolled studies have suggested an interaction between ticlopidine, a major antiplatelet agent, and cyclosporin in heart- and kidney-transplant recipients.
Barthelemy, J. C. +8 more
core +2 more sources
The new antiaggregants: Ticlopidine and Clopidogrel
İnönü Üniversitesi Tıp Fakültesi Dergisi 10(3) 163-165 (2003)Tiklopidin ve klopidogrelin etki mekanizmaları literatür ışığında gözden geçirilmiştirThe effects of ticlopidine and clopidogrel are ...
BOLAYIR, Ertuğrul
core +1 more source
Inactivation of Cytochrome P450 2B6 by Ticlopidine and Clopidogrel
34 p.In this study, the inhibition of cytochrome P450 2B6 (2B6) by ticlopidine and clopidogrel was analyzed. It was determined that ticlopidine and clopidogrel were potent mechanism-based inactivators of2B6 confirming previous research (Nishiya et al ...
Cooper, Nyemade
core
A Case of Ticlopidine-induced Neutropenia Treated with rhG-CSF [PDF]
There are many conditions which are associated with neutropenia, such as infections, chemical and physical agents, and hematopoietic diseases. But ticlopidine-induced neutropenis is rarely reported in Korea.
안철우, 임세중
core
The bleeding costs of intensive vs. less intensive antithrombotic strategies: a meta-regression analysis. [PDF]
Deurvorst SE +5 more
europepmc +1 more source
Antithrombotic Drug Eruptions in Dermatology Practice: Selection Bias, Clinical Phenotypes, and Diagnostic Approaches. [PDF]
Takada T.
europepmc +1 more source
Non-Systemic Oral Cellulose-Based Superabsorbent Hydrogels for Weight Management: Potential Drug-Device Interactions Estimated by a Simplified In Vitro Assay. [PDF]
Panteca E +5 more
europepmc +1 more source
Cerebral DWI lesion burden following carotid artery stenting with guided antiplatelet therapy: a retrospective comparative study. [PDF]
Vigláš P +8 more
europepmc +1 more source

